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| Information on 1h8e_A_354 |
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Loop code: 1h8e_A_354 PDB: 1h8e Chain: A Type: HH alpha-alpha |
Loop Start: 354 Loop Length: 22 Sec Struct Nt length: 5 Sec Struct Ct length: 20 Structure geometry
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| Sequence: | TELFYKGIRPAINVGLSVSRVGSAAQTRAMKQVAGTMKLELAQYREV |
| Sec Struct: | HHHHHTT-SS-B-TTT---SSGGGGS-HHHHHHHHHHHHHHHHHHHH |
| PDB ligands within a cut-off distance of 6 Å in this loop |
| Ligands | Residue | atSS | atLOOP |
| ADPADENOSINE-5'-DIPHOSPHATE | F - 357 | 0 | 1 |
| ADPADENOSINE-5'-DIPHOSPHATE | R - 362 | 0 | 1 |
| ADPADENOSINE-5'-DIPHOSPHATE | P - 363 | 0 | 1 |
| ADPADENOSINE-5'-DIPHOSPHATE | S - 372 | 0 | 1 |
| ADPADENOSINE-5'-DIPHOSPHATE | R - 373 | 0 | 1 |
| MGMAGNESIUM ION | R - 373 | 0 | 1 |
| ADPADENOSINE-5'-DIPHOSPHATE | V - 374 | 0 | 1 |
| ADPADENOSINE-5'-DIPHOSPHATE | G - 375 | 0 | 1 |
| ADPADENOSINE-5'-DIPHOSPHATE | S - 376 | 0 | 1 |
| PDB Site Annotation |
| Site | Residue | atSS | atLOOP |
| BC1 - ADP BINDING SITE FOR CHAIN E | R - 373 | 0 | 1 |
| BC3 - SO4 BINDING SITE FOR CHAIN E | R - 373 | 0 | 1 |
| CAT - THE CARBOXYLATE GROUP OF THE GLUTAMIC ACID RESIDUE IS BELIEVED TO ACTIVATE A WATER MOLECULE FOR INLINE ATTACK ON THE GAMMA PHOSPHATE DURING ATP HYDROLYSIS. THE ARGININE RESIDUE (WHICH IS LOCATED ON A ADJACENT ALPHA SUBUNIT) COULD HELP TO STABLIZE THE NEGATIVE CHARGE THAT DEVELOPS ON THE TERMINAL PHOSPHATE IN THE PUTATIVE PENTACOORDINATED TRANSITION STATE. | R - 373 | 0 | 1 |
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