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Information on 1a22
PDB: 1a22
Compound: growth hormone
Classification: COMPLEX (HORMONE/RECEPTOR)
Entry date in PDB: 1998-04-29
Resolution [Å]: 2.60
R-Factor: 0.187


CHAIN: A
SWISS-PROT/TREMBL: P01241
   KEYWORD: 3D-structure    Alternative splicing    Disease mutation    Dwarfism    Hormone    Pharmaceutical    Phosphorylation    Pituitary    Polymorphism    Signal   
SCOP: a.26.1.1 All alpha proteins    4-helical cytokines    4-helical cytokines    Long-chain cytokines    Growth hormone, somatotropin    Human (Homo sapiens)
GO:  extracellular region    hormone activity   


CHAIN: B
SWISS-PROT/TREMBL: P10912
   KEYWORD: 3D-structure    Alternative splicing    Disease mutation    Dwarfism    Endocytosis    Glycoprotein    Phosphorylation    Polymorphism    Receptor    Signal    Transmembrane    Ubl conjugation   
SCOP: b.1.2.1 All beta proteins    Immunoglobulin-like beta-sandwich    Fibronectin type III    Fibronectin type III    Growth hormone receptor    Human (Homo sapiens)
SCOP: b.1.2.1 All beta proteins    Immunoglobulin-like beta-sandwich    Fibronectin type III    Fibronectin type III    Growth hormone receptor    Human (Homo sapiens)
GO:  membrane    hematopoietin/interferon-class (D200-domain) cytokine receptor activity   
1a22 Image
Image Source: PDB
Homologous structures to 1a22 classified in ArchDB

1axi B - percentage of sequence identity: 98
1huw - - percentage of sequence identity: 91