PDB: 1a35 Compound: topoisomerase i Classification: COMPLEX (ISOMERASE/DNA) Entry date in PDB: 1998-08-26 Resolution [Å]: 2.50 R-Factor: 0.209

CHAIN: A SWISS-PROT/TREMBL: P11387    KEYWORD: 3D-structure    Chromosomal translocation    DNA-binding    Isomerase    Polymorphism    Proto-oncogene    Topoisomerase    EC: 5.99.1.2 SCOP: d.163.1.2 Alpha and beta proteins (a+b)    DNA breaking-rejoining enzymes    DNA breaking-rejoining enzymes    Eukaryotic DNA topoisomerase I, catalytic core    Eukaryotic DNA topoisomerase I, catalytic core    Human (Homo sapiens) SCOP: d.163.1.2 Alpha and beta proteins (a+b)    DNA breaking-rejoining enzymes    DNA breaking-rejoining enzymes    Eukaryotic DNA topoisomerase I, catalytic core    Eukaryotic DNA topoisomerase I, catalytic core    Human (Homo sapiens) SCOP: e.15.1.1 Multi-domain proteins (alpha and beta)    Eukaryotic DNA topoisomerase I, N-terminal DNA-binding fragment    Eukaryotic DNA topoisomerase I, N-terminal DNA-binding fragment    Eukaryotic DNA topoisomerase I, N-terminal DNA-binding fragment    Eukaryotic DNA topoisomerase I, N-terminal DNA-binding fragment    Human (Homo sapiens) GO:  DNA binding    DNA topoisomerase type I activity    DNA topological change    DNA unwinding

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1a31 A - percentage of sequence identity: 99
1k4t A - percentage of sequence identity: 99