PDB: 1azs Compound: vc1 Classification: COMPLEX (LYASE/HYDROLASE) Entry date in PDB: 1998-02-25 Resolution [Å]: 2.30 R-Factor: 0.219

CHAIN: A SWISS-PROT/TREMBL: P30803    KEYWORD: 3D-structure    Alternative splicing    cAMP biosynthesis    Glycoprotein    Lyase    Magnesium    Metal-binding    Repeat    Transmembrane    EC: 4.6.1.1 SCOP: d.58.29.1 Alpha and beta proteins (a+b)    Ferredoxin-like    Adenylyl and guanylyl cyclase catalytic domain    Adenylyl and guanylyl cyclase catalytic domain    Adenylyl cyclase VC1, domain C1a    Dog (Canis familiaris) GO:  integral to membrane    adenylate cyclase activity    phosphorus-oxygen lyase activity    cyclic nucleotide biosynthesis    intracellular signaling cascade    CHAIN: B SWISS-PROT/TREMBL: P26769    KEYWORD: 3D-structure    cAMP biosynthesis    Glycoprotein    Lyase    Magnesium    Metal-binding    Repeat    Transmembrane    EC: 4.6.1.1 SCOP: d.58.29.1 Alpha and beta proteins (a+b)    Ferredoxin-like    Adenylyl and guanylyl cyclase catalytic domain    Adenylyl and guanylyl cyclase catalytic domain    Adenylyl cyclase IIC1, domain C2a    Rat (Rattus norvegicus) GO:  integral to membrane    adenylate cyclase activity    phosphorus-oxygen lyase activity    cyclic nucleotide biosynthesis    intracellular signaling cascade    CHAIN: C SWISS-PROT/TREMBL: P04896    KEYWORD: 3D-structure    ADP-ribosylation    Alternative splicing    GTP-binding    Lipoprotein    Multigene family    Palmitate    Transducer    SCOP: a.66.1.1 All alpha proteins    Transducin (alpha subunit), insertion domain    Transducin (alpha subunit), insertion domain    Transducin (alpha subunit), insertion domain    Transducin (alpha subunit), insertion domain    Cow (Bos taurus) SCOP: c.37.1.8 Alpha and beta proteins (a/b)    P-loop containing nucleoside triphosphate hydrolases    P-loop containing nucleoside triphosphate hydrolases    G proteins    Transducin (alpha subunit)    Cow (Bos taurus) SCOP: c.37.1.8 Alpha and beta proteins (a/b)    P-loop containing nucleoside triphosphate hydrolases    P-loop containing nucleoside triphosphate hydrolases    G proteins    Transducin (alpha subunit)    Cow (Bos taurus) GO:  GTP binding    signal transducer activity    G-protein coupled receptor protein signaling pathway    signal transduction

Image Source: PDB

Loops in ArchDB40 clusters

1azs_A_409 - HE => SUBCLASS : 1.1.3
1azs_B_1043 - HE => SUBCLASS : 2.2.10
1azs_A_552 - HE => SUBCLASS : 4.10.1
1azs_B_1022 - HE => SUBCLASS : 4.27.1
1azs_A_509 - HE => SUBCLASS : 4.27.1
1azs_A_509 - HE => SUBCLASS : 4.35.1
1azs_B_1022 - HE => SUBCLASS : 5.12.2
1azs_B_967 - HE => SUBCLASS : 5.32.1
1azs_C_265 - HE => SUBCLASS : 7.2.1
1azs_C_207 - HA => SUBCLASS : 2.1.1
1azs_A_432 - HA => SUBCLASS : 2.3.6
1azs_B_881 - EH => SUBCLASS : 1.1.27
1azs_A_505 - EH => SUBCLASS : 1.2.10
1azs_B_1016 - EH => SUBCLASS : 1.2.10
1azs_B_1016 - EH => SUBCLASS : 1.2.12
1azs_A_505 - EH => SUBCLASS : 1.2.12
1azs_C_287 - EH => SUBCLASS : 1.4.1
1azs_C_359 - EH => SUBCLASS : 4.1.1
1azs_C_40 - EH => SUBCLASS : 6.1.1
1azs_A_400 - HH => SUBCLASS : 2.1.3

Loops in ArchDB95 clusters

1azs_B_881 - EH => SUBCLASS : 0.1.37
1azs_A_505 - EH => SUBCLASS : 1.3.13
1azs_B_1016 - EH => SUBCLASS : 1.3.13
1azs_C_359 - EH => SUBCLASS : 4.1.1
1azs_C_40 - EH => SUBCLASS : 6.1.1
1azs_C_217 - AR => SUBCLASS : 18.1.1
1azs_A_400 - HH => SUBCLASS : 2.3.1
1azs_C_157 - HH => SUBCLASS : 4.17.2
1azs_A_409 - HE => SUBCLASS : 1.2.5
1azs_B_1043 - HE => SUBCLASS : 2.1.1
1azs_A_552 - HE => SUBCLASS : 4.5.2
1azs_B_967 - HE => SUBCLASS : 4.24.1
1azs_A_509 - HE => SUBCLASS : 5.8.2
1azs_C_265 - HE => SUBCLASS : 7.2.1
1azs_C_265 - HE => SUBCLASS : 8.8.1
1azs_C_207 - HA => SUBCLASS : 2.1.1
1azs_A_432 - HA => SUBCLASS : 2.3.3

Loops in ArchDB-EC clusters

1azs_A_400 - HH => SUBCLASS : 2.1.1

Loops not clustered in ArchDB

1azs_A_526 - AR
1azs_A_526 - AR
1azs_A_383 - EH
1azs_C_243 - EH
1azs_B_1038 - EH
1azs_B_943 - EH
1azs_A_542 - EH
1azs_A_441 - EH
1azs_B_997 - HA
1azs_A_482 - HA
1azs_A_432 - HA
1azs_B_1056 - HA
1azs_B_934 - HA
1azs_B_1056 - HA
1azs_B_997 - HA
1azs_A_482 - HA
1azs_B_934 - HA
1azs_A_455 - HE
1azs_B_909 - HE
1azs_C_194 - HE
1azs_C_332 - HE
1azs_C_175 - HH
1azs_C_144 - HH
1azs_C_294 - HH
1azs_C_125 - HH
1azs_C_90 - HH
1azs_B_895 - HH
1azs_C_53 - HH
1azs_C_182 - HH

1cjk A - percentage of sequence identity: 100
1cjt A - percentage of sequence identity: 100
1cju A - percentage of sequence identity: 100
1cjv A - percentage of sequence identity: 100
1cs4 A - percentage of sequence identity: 100
1cul A - percentage of sequence identity: 100
1tl7 A - percentage of sequence identity: 100
1u0h A - percentage of sequence identity: 100