PDB: 1b47 Compound: cbl Classification: SIGNAL TRANSDUCTION Entry date in PDB: 1999-04-27 Resolution [Å]: 2.20 R-Factor: 0.218

CHAIN: A SWISS-PROT/TREMBL: P22681    KEYWORD: 3D-structure    Calcium-binding    Ligase    Phosphorylation    Proto-oncogene    SH2 domain    Ubl conjugation pathway    Zinc-finger    EC: 6.3.2.- SCOP: a.39.1.7 All alpha proteins    EF Hand-like    EF-hand    EF-hand modules in multidomain proteins    Cbl    Human (Homo sapiens) SCOP: a.48.1.1 All alpha proteins    N-cbl like    N-terminal domain of cbl (N-cbl)    N-terminal domain of cbl (N-cbl)    N-terminal domain of cbl (N-cbl)    Human (Homo sapiens) SCOP: d.93.1.1 Alpha and beta proteins (a+b)    SH2-like    SH2 domain    SH2 domain    Cbl    Human (Homo sapiens) GO:  nucleus    ubiquitin ligase complex    calcium ion binding    signal transducer activity    ubiquitin-protein ligase activity    zinc ion binding    cell surface receptor linked signal transduction    protein ubiquitination    CHAIN: B SWISS-PROT/TREMBL: P22681    KEYWORD: 3D-structure    Calcium-binding    Ligase    Phosphorylation    Proto-oncogene    SH2 domain    Ubl conjugation pathway    Zinc-finger    EC: 6.3.2.- SCOP: a.39.1.7 All alpha proteins    EF Hand-like    EF-hand    EF-hand modules in multidomain proteins    Cbl    Human (Homo sapiens) SCOP: a.48.1.1 All alpha proteins    N-cbl like    N-terminal domain of cbl (N-cbl)    N-terminal domain of cbl (N-cbl)    N-terminal domain of cbl (N-cbl)    Human (Homo sapiens) SCOP: d.93.1.1 Alpha and beta proteins (a+b)    SH2-like    SH2 domain    SH2 domain    Cbl    Human (Homo sapiens) GO:  nucleus    ubiquitin ligase complex    calcium ion binding    signal transducer activity    ubiquitin-protein ligase activity    zinc ion binding    cell surface receptor linked signal transduction    protein ubiquitination    CHAIN: C SWISS-PROT/TREMBL: P22681    KEYWORD: 3D-structure    Calcium-binding    Ligase    Phosphorylation    Proto-oncogene    SH2 domain    Ubl conjugation pathway    Zinc-finger    EC: 6.3.2.- SCOP: a.39.1.7 All alpha proteins    EF Hand-like    EF-hand    EF-hand modules in multidomain proteins    Cbl    Human (Homo sapiens) SCOP: a.48.1.1 All alpha proteins    N-cbl like    N-terminal domain of cbl (N-cbl)    N-terminal domain of cbl (N-cbl)    N-terminal domain of cbl (N-cbl)    Human (Homo sapiens) SCOP: d.93.1.1 Alpha and beta proteins (a+b)    SH2-like    SH2 domain    SH2 domain    Cbl    Human (Homo sapiens) GO:  nucleus    ubiquitin ligase complex    calcium ion binding    signal transducer activity    ubiquitin-protein ligase activity    zinc ion binding    cell surface receptor linked signal transduction    protein ubiquitination

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2cbl A - percentage of sequence identity: 100