PDB: 1bi8 Compound: cyclin-dependent kinase 6 Classification: COMPLEX (KINASE/INHIBITOR) Entry date in PDB: 1999-01-13 Resolution [Å]: 2.80 R-Factor: 0.255

CHAIN: A SWISS-PROT/TREMBL: Q00534    KEYWORD: 3D-structure    ATP-binding    Cell cycle    Cell division    Phosphorylation    Serine/threonine-protein kinase    Transferase    EC: 2.7.1.37 SCOP: d.144.1.7 Alpha and beta proteins (a+b)    Protein kinase-like (PK-like)    Protein kinase-like (PK-like)    Protein kinases, catalytic subunit    Cyclin-dependent PK, CDK6    Human (Homo sapiens) GO:  ATP binding    protein kinase activity    protein serine/threonine kinase activity    protein amino acid phosphorylation    CHAIN: B SWISS-PROT/TREMBL: P55273    KEYWORD: 3D-structure    ANK repeat    Anti-oncogene    Cell cycle    Repeat    SCOP: d.211.1.1 Alpha and beta proteins (a+b)    beta-hairpin-alpha-hairpin repeat    Ankyrin repeat    Ankyrin repeat    Cell cycle inhibitor p19ink4D    Human (Homo sapiens) GO:   CHAIN: C SWISS-PROT/TREMBL: Q00534    KEYWORD: 3D-structure    ATP-binding    Cell cycle    Cell division    Phosphorylation    Serine/threonine-protein kinase    Transferase    EC: 2.7.1.37 SCOP: d.144.1.7 Alpha and beta proteins (a+b)    Protein kinase-like (PK-like)    Protein kinase-like (PK-like)    Protein kinases, catalytic subunit    Cyclin-dependent PK, CDK6    Human (Homo sapiens) GO:  ATP binding    protein kinase activity    protein serine/threonine kinase activity    protein amino acid phosphorylation    CHAIN: D SWISS-PROT/TREMBL: P55273    KEYWORD: 3D-structure    ANK repeat    Anti-oncogene    Cell cycle    Repeat    SCOP: d.211.1.1 Alpha and beta proteins (a+b)    beta-hairpin-alpha-hairpin repeat    Ankyrin repeat    Ankyrin repeat    Cell cycle inhibitor p19ink4D    Human (Homo sapiens) GO:

Image Source: PDB

Loops in ArchDB-EC clusters

1bi8_A_199 - HH => SUBCLASS : 9.3.1

Loops in ArchDB-KI clusters

1bi8_A_151 - HA => SUBCLASS : 4.2.1
1bi8_A_119 - HE => SUBCLASS : 11.1.1

Loops not clustered in ArchDB

1bi8_A_159 - AR
1bi8_A_39 - AR
1bi8_A_93 - EH
1bi8_A_180 - EH
1bi8_A_151 - HA
1bi8_A_79 - HA
1bi8_A_26 - HA
1bi8_A_14 - HA
1bi8_A_169 - HA
1bi8_A_119 - HE
1bi8_A_271 - HH
1bi8_A_224 - HH
1bi8_A_188 - HH
1bi8_A_105 - HH

Loops not clustered in ArchDB-KI

1bi8_A_159 - AR
1bi8_A_39 - AR
1bi8_A_93 - EH
1bi8_A_180 - EH
1bi8_A_26 - HA
1bi8_A_169 - HA
1bi8_A_79 - HA
1bi8_A_14 - HA
1bi8_A_271 - HH
1bi8_A_105 - HH
1bi8_A_188 - HH
1bi8_A_224 - HH
1bi8_A_199 - HH

1bd8 - - percentage of sequence identity: 100
1bi7 A - percentage of sequence identity: 100
1bi8 A - percentage of sequence identity: 100
1bi8 C - percentage of sequence identity: 100
1blx A - percentage of sequence identity: 100
1blx B - percentage of sequence identity: 86
1g3n A - percentage of sequence identity: 100
1g3n E - percentage of sequence identity: 100
1jow B - percentage of sequence identity: 100
1xo2 B - percentage of sequence identity: 100