PDB: 1bth Compound: thrombin Classification: COMPLEX (SERINE PROTEASE/INHIBITOR) Entry date in PDB: 1997-12-24 Resolution [Å]: 2.30 R-Factor: 0.196

CHAIN: H SWISS-PROT/TREMBL: P00734    KEYWORD: 3D-structure    Acute phase    Blood coagulation    Calcium-binding    Disease mutation    Gamma-carboxyglutamic acid    Glycoprotein    Hydrolase    Kringle    Plasma    Polymorphism    Repeat    Serine protease    Signal    Vitamin K    Zymogen    EC: 3.4.21.5 SCOP: b.47.1.2 All beta proteins    Trypsin-like serine proteases    Trypsin-like serine proteases    Eukaryotic proteases    Thrombin    Cow (Bos taurus) GO:  extracellular region    calcium ion binding    chymotrypsin activity    thrombin activity    trypsin activity    blood coagulation    proteolysis and peptidolysis    CHAIN: J SWISS-PROT/TREMBL: P00734    KEYWORD: 3D-structure    Acute phase    Blood coagulation    Calcium-binding    Disease mutation    Gamma-carboxyglutamic acid    Glycoprotein    Hydrolase    Kringle    Plasma    Polymorphism    Repeat    Serine protease    Signal    Vitamin K    Zymogen    EC: 3.4.21.5 SCOP: b.47.1.2 All beta proteins    Trypsin-like serine proteases    Trypsin-like serine proteases    Eukaryotic proteases    Thrombin    Cow (Bos taurus) GO:  extracellular region    calcium ion binding    chymotrypsin activity    thrombin activity    trypsin activity    blood coagulation    proteolysis and peptidolysis    CHAIN: K SWISS-PROT/TREMBL: P00734    KEYWORD: 3D-structure    Acute phase    Blood coagulation    Calcium-binding    Disease mutation    Gamma-carboxyglutamic acid    Glycoprotein    Hydrolase    Kringle    Plasma    Polymorphism    Repeat    Serine protease    Signal    Vitamin K    Zymogen    EC: 3.4.21.5 SCOP: b.47.1.2 All beta proteins    Trypsin-like serine proteases    Trypsin-like serine proteases    Eukaryotic proteases    Thrombin    Cow (Bos taurus) GO:  extracellular region    calcium ion binding    chymotrypsin activity    thrombin activity    trypsin activity    blood coagulation    proteolysis and peptidolysis    CHAIN: L SWISS-PROT/TREMBL: P00734    KEYWORD: 3D-structure    Acute phase    Blood coagulation    Calcium-binding    Disease mutation    Gamma-carboxyglutamic acid    Glycoprotein    Hydrolase    Kringle    Plasma    Polymorphism    Repeat    Serine protease    Signal    Vitamin K    Zymogen    EC: 3.4.21.5 SCOP: b.47.1.2 All beta proteins    Trypsin-like serine proteases    Trypsin-like serine proteases    Eukaryotic proteases    Thrombin    Cow (Bos taurus) GO:  extracellular region    calcium ion binding    chymotrypsin activity    thrombin activity    trypsin activity    blood coagulation    proteolysis and peptidolysis    CHAIN: P SWISS-PROT/TREMBL: P00974    KEYWORD: 3D-structure    Pharmaceutical    Serine protease inhibitor    Signal    SCOP: g.8.1.1 Small proteins    BPTI-like    BPTI-like    Small Kunitz-type inhibitors & BPTI-like toxins    Pancreatic trypsin inhibitor, BPTI    Cow (Bos taurus) GO:  serine-type endopeptidase inhibitor activity    CHAIN: Q SWISS-PROT/TREMBL: P00974    KEYWORD: 3D-structure    Pharmaceutical    Serine protease inhibitor    Signal    SCOP: g.8.1.1 Small proteins    BPTI-like    BPTI-like    Small Kunitz-type inhibitors & BPTI-like toxins    Pancreatic trypsin inhibitor, BPTI    Cow (Bos taurus) GO:  serine-type endopeptidase inhibitor activity

Image Source: PDB

1etr H - percentage of sequence identity: 87
1fak I - percentage of sequence identity: 85
1h8d H - percentage of sequence identity: 96
1jou B - percentage of sequence identity: 98
1ucy H - percentage of sequence identity: 86
1vr1 H - percentage of sequence identity: 96
2hnt F - percentage of sequence identity: 99
5pti - - percentage of sequence identity: 100
null nu - percentage of sequence identity: 0