PDB: 1bwn Compound: bruton's tyrosine kinase Classification: TRANSFERASE Entry date in PDB: 1999-06-15 Resolution [Å]: 2.10 R-Factor: 0.214

CHAIN: A SWISS-PROT/TREMBL: Q06187    KEYWORD: 3D-structure    ATP-binding    Disease mutation    Metal-binding    Phosphorylation    Polymorphism    SH2 domain    SH3 domain    Transferase    Tyrosine-protein kinase    Zinc    EC: 2.7.1.112 SCOP: b.55.1.1 All beta proteins    PH domain-like    PH domain-like    Pleckstrin-homology domain (PH domain)    Bruton's tyrosine kinase    Human (Homo sapiens) GO:  ATP binding    protein kinase activity    protein-tyrosine kinase activity    intracellular signaling cascade    protein amino acid phosphorylation    CHAIN: B SWISS-PROT/TREMBL: Q06187    KEYWORD: 3D-structure    ATP-binding    Disease mutation    Metal-binding    Phosphorylation    Polymorphism    SH2 domain    SH3 domain    Transferase    Tyrosine-protein kinase    Zinc    EC: 2.7.1.112 SCOP: b.55.1.1 All beta proteins    PH domain-like    PH domain-like    Pleckstrin-homology domain (PH domain)    Bruton's tyrosine kinase    Human (Homo sapiens) GO:  ATP binding    protein kinase activity    protein-tyrosine kinase activity    intracellular signaling cascade    protein amino acid phosphorylation

Image Source: PDB

1btk A - percentage of sequence identity: 98