PDB: 1cer Compound: holo-d-glyceraldehyde-3-phosphate dehydrogenase Classification: OXIDOREDUCTASE (ALDEHYDE(D)-NAD(A)) Entry date in PDB: 1996-03-08 Resolution [Å]: 2.50 R-Factor: 0.205

CHAIN: O SWISS-PROT/TREMBL: P00361    KEYWORD: 3D-structure    Glycolysis    NAD    Oxidoreductase    EC: 1.2.1.12 SCOP: c.2.1.3 Alpha and beta proteins (a/b)    NAD(P)-binding Rossmann-fold domains    NAD(P)-binding Rossmann-fold domains    Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain    Glyceraldehyde-3-phosphate dehydrogenase (GAPDH)    Thermus aquaticus SCOP: c.2.1.3 Alpha and beta proteins (a/b)    NAD(P)-binding Rossmann-fold domains    NAD(P)-binding Rossmann-fold domains    Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain    Glyceraldehyde-3-phosphate dehydrogenase (GAPDH)    Thermus aquaticus SCOP: d.81.1.1 Alpha and beta proteins (a+b)    Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain    Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain    GAPDH-like    Glyceraldehyde-3-phosphate dehydrogenase (GAPDH)    Thermus aquaticus GO:  glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) activity    glyceraldehyde-3-phosphate dehydrogenase activity    NAD binding    glucose metabolism    glycolysis    CHAIN: P SWISS-PROT/TREMBL: P00361    KEYWORD: 3D-structure    Glycolysis    NAD    Oxidoreductase    EC: 1.2.1.12 SCOP: c.2.1.3 Alpha and beta proteins (a/b)    NAD(P)-binding Rossmann-fold domains    NAD(P)-binding Rossmann-fold domains    Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain    Glyceraldehyde-3-phosphate dehydrogenase (GAPDH)    Thermus aquaticus SCOP: c.2.1.3 Alpha and beta proteins (a/b)    NAD(P)-binding Rossmann-fold domains    NAD(P)-binding Rossmann-fold domains    Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain    Glyceraldehyde-3-phosphate dehydrogenase (GAPDH)    Thermus aquaticus SCOP: d.81.1.1 Alpha and beta proteins (a+b)    Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain    Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain    GAPDH-like    Glyceraldehyde-3-phosphate dehydrogenase (GAPDH)    Thermus aquaticus GO:  glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) activity    glyceraldehyde-3-phosphate dehydrogenase activity    NAD binding    glucose metabolism    glycolysis    CHAIN: Q SWISS-PROT/TREMBL: P00361    KEYWORD: 3D-structure    Glycolysis    NAD    Oxidoreductase    EC: 1.2.1.12 SCOP: c.2.1.3 Alpha and beta proteins (a/b)    NAD(P)-binding Rossmann-fold domains    NAD(P)-binding Rossmann-fold domains    Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain    Glyceraldehyde-3-phosphate dehydrogenase (GAPDH)    Thermus aquaticus SCOP: c.2.1.3 Alpha and beta proteins (a/b)    NAD(P)-binding Rossmann-fold domains    NAD(P)-binding Rossmann-fold domains    Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain    Glyceraldehyde-3-phosphate dehydrogenase (GAPDH)    Thermus aquaticus SCOP: d.81.1.1 Alpha and beta proteins (a+b)    Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain    Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain    GAPDH-like    Glyceraldehyde-3-phosphate dehydrogenase (GAPDH)    Thermus aquaticus GO:  glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) activity    glyceraldehyde-3-phosphate dehydrogenase activity    NAD binding    glucose metabolism    glycolysis    CHAIN: R SWISS-PROT/TREMBL: P00361    KEYWORD: 3D-structure    Glycolysis    NAD    Oxidoreductase    EC: 1.2.1.12 SCOP: c.2.1.3 Alpha and beta proteins (a/b)    NAD(P)-binding Rossmann-fold domains    NAD(P)-binding Rossmann-fold domains    Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain    Glyceraldehyde-3-phosphate dehydrogenase (GAPDH)    Thermus aquaticus SCOP: c.2.1.3 Alpha and beta proteins (a/b)    NAD(P)-binding Rossmann-fold domains    NAD(P)-binding Rossmann-fold domains    Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain    Glyceraldehyde-3-phosphate dehydrogenase (GAPDH)    Thermus aquaticus SCOP: d.81.1.1 Alpha and beta proteins (a+b)    Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain    Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain    GAPDH-like    Glyceraldehyde-3-phosphate dehydrogenase (GAPDH)    Thermus aquaticus GO:  glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) activity    glyceraldehyde-3-phosphate dehydrogenase activity    NAD binding    glucose metabolism    glycolysis

Image Source: PDB

Loops in ArchDB95 clusters

1cer_O_204 - EH => SUBCLASS : 2.2.14
1cer_O_27 - EH => SUBCLASS : 3.4.1
1cer_O_271 - EH => SUBCLASS : 5.4.1
1cer_O_238 - EH => SUBCLASS : 5.10.1
1cer_O_89 - EH => SUBCLASS : 7.10.2
1cer_O_290 - AR => SUBCLASS : 3.2.3
1cer_O_115 - AR => SUBCLASS : 8.31.1
1cer_O_167 - AR => SUBCLASS : 25.1.1
1cer_O_84 - HE => SUBCLASS : 1.2.5
1cer_O_10 - HE => SUBCLASS : 2.1.1
1cer_O_10 - HE => SUBCLASS : 2.1.2
1cer_O_102 - HE => SUBCLASS : 3.1.6
1cer_O_252 - HE => SUBCLASS : 6.11.1
1cer_O_57 - HA => SUBCLASS : 2.2.3
1cer_O_298 - HA => SUBCLASS : 2.6.3

Loops in ArchDB-EC clusters

1cer_O_252 - HE => SUBCLASS : 6.8.1

Loops not clustered in ArchDB

1cer_O_225 - AR
1cer_O_115 - AR
1cer_O_167 - AR
1cer_O_225 - AR
1cer_O_290 - AR
1cer_O_304 - EH
1cer_O_143 - EH
1cer_O_69 - EH
1cer_O_2 - EH
1cer_O_126 - HA
1cer_O_63 - HA
1cer_O_57 - HA
1cer_O_126 - HA
1cer_O_63 - HA
1cer_O_298 - HA
1cer_O_280 - HE
1cer_O_210 - HE
1cer_O_149 - HE
1cer_O_37 - HE

1cer A - percentage of sequence identity: 100
1cer B - percentage of sequence identity: 100
1cer C - percentage of sequence identity: 100
1cer D - percentage of sequence identity: 100
1cer O - percentage of sequence identity: 100
1cer P - percentage of sequence identity: 100
1cer Q - percentage of sequence identity: 100
1cer R - percentage of sequence identity: 100
1dbv O - percentage of sequence identity: 61
1dbv P - percentage of sequence identity: 61
1dbv Q - percentage of sequence identity: 61
1dbv R - percentage of sequence identity: 61
1gd1 O - percentage of sequence identity: 62
1gd1 P - percentage of sequence identity: 62
1gd1 Q - percentage of sequence identity: 62
1gd1 R - percentage of sequence identity: 62
1hdg O - percentage of sequence identity: 61
1hdg Q - percentage of sequence identity: 61
1npt O - percentage of sequence identity: 62
1npt P - percentage of sequence identity: 62
1npt Q - percentage of sequence identity: 62
1npt R - percentage of sequence identity: 62
1nq5 A - percentage of sequence identity: 62
1nq5 C - percentage of sequence identity: 62
1nq5 O - percentage of sequence identity: 62
1nq5 Q - percentage of sequence identity: 62
1nqa O - percentage of sequence identity: 62
1nqa P - percentage of sequence identity: 62
1nqa Q - percentage of sequence identity: 62
1nqa R - percentage of sequence identity: 62
1nqo A - percentage of sequence identity: 62
1nqo C - percentage of sequence identity: 62
1nqo O - percentage of sequence identity: 62
1nqo Q - percentage of sequence identity: 62
1vc2 A - percentage of sequence identity: 90
2dbv O - percentage of sequence identity: 61
2dbv P - percentage of sequence identity: 61
2dbv Q - percentage of sequence identity: 61
2dbv R - percentage of sequence identity: 61
2gd1 O - percentage of sequence identity: 62
2gd1 P - percentage of sequence identity: 62
2gd1 Q - percentage of sequence identity: 62
2gd1 R - percentage of sequence identity: 62
3dbv O - percentage of sequence identity: 61
3dbv P - percentage of sequence identity: 61
3dbv Q - percentage of sequence identity: 61
3dbv R - percentage of sequence identity: 61
4dbv O - percentage of sequence identity: 61
4dbv P - percentage of sequence identity: 61
4dbv Q - percentage of sequence identity: 61
4dbv R - percentage of sequence identity: 61