PDB: 1cf2 Compound: glyceraldehyde-3-phosphate dehydrogenase Classification: OXIDOREDUCTASE Entry date in PDB: 2000-03-24 Resolution [Å]: 2.10 R-Factor: 0.194

CHAIN: O SWISS-PROT/TREMBL: P10618    KEYWORD: 3D-structure    Glycolysis    NAD    NADP    Oxidoreductase    EC: 1.2.1.59 SCOP: c.2.1.3 Alpha and beta proteins (a/b)    NAD(P)-binding Rossmann-fold domains    NAD(P)-binding Rossmann-fold domains    Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain    Glyceraldehyde-3-phosphate dehydrogenase (GAPDH)    Archaeon Methanothermus fervidus SCOP: c.2.1.3 Alpha and beta proteins (a/b)    NAD(P)-binding Rossmann-fold domains    NAD(P)-binding Rossmann-fold domains    Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain    Glyceraldehyde-3-phosphate dehydrogenase (GAPDH)    Archaeon Methanothermus fervidus SCOP: d.81.1.1 Alpha and beta proteins (a+b)    Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain    Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain    GAPDH-like    Glyceraldehyde-3-phosphate dehydrogenase (GAPDH)    Archaeon Methanothermus fervidus GO:  cytoplasm    glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) activity    glyceraldehyde-3-phosphate dehydrogenase activity    NAD binding    NADP binding    glycolysis    CHAIN: P SWISS-PROT/TREMBL: P10618    KEYWORD: 3D-structure    Glycolysis    NAD    NADP    Oxidoreductase    EC: 1.2.1.59 SCOP: c.2.1.3 Alpha and beta proteins (a/b)    NAD(P)-binding Rossmann-fold domains    NAD(P)-binding Rossmann-fold domains    Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain    Glyceraldehyde-3-phosphate dehydrogenase (GAPDH)    Archaeon Methanothermus fervidus SCOP: c.2.1.3 Alpha and beta proteins (a/b)    NAD(P)-binding Rossmann-fold domains    NAD(P)-binding Rossmann-fold domains    Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain    Glyceraldehyde-3-phosphate dehydrogenase (GAPDH)    Archaeon Methanothermus fervidus SCOP: d.81.1.1 Alpha and beta proteins (a+b)    Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain    Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain    GAPDH-like    Glyceraldehyde-3-phosphate dehydrogenase (GAPDH)    Archaeon Methanothermus fervidus GO:  cytoplasm    glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) activity    glyceraldehyde-3-phosphate dehydrogenase activity    NAD binding    NADP binding    glycolysis    CHAIN: Q SWISS-PROT/TREMBL: P10618    KEYWORD: 3D-structure    Glycolysis    NAD    NADP    Oxidoreductase    EC: 1.2.1.59 SCOP: c.2.1.3 Alpha and beta proteins (a/b)    NAD(P)-binding Rossmann-fold domains    NAD(P)-binding Rossmann-fold domains    Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain    Glyceraldehyde-3-phosphate dehydrogenase (GAPDH)    Archaeon Methanothermus fervidus SCOP: c.2.1.3 Alpha and beta proteins (a/b)    NAD(P)-binding Rossmann-fold domains    NAD(P)-binding Rossmann-fold domains    Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain    Glyceraldehyde-3-phosphate dehydrogenase (GAPDH)    Archaeon Methanothermus fervidus SCOP: d.81.1.1 Alpha and beta proteins (a+b)    Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain    Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain    GAPDH-like    Glyceraldehyde-3-phosphate dehydrogenase (GAPDH)    Archaeon Methanothermus fervidus GO:  cytoplasm    glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) activity    glyceraldehyde-3-phosphate dehydrogenase activity    NAD binding    NADP binding    glycolysis    CHAIN: R SWISS-PROT/TREMBL: P10618    KEYWORD: 3D-structure    Glycolysis    NAD    NADP    Oxidoreductase    EC: 1.2.1.59 SCOP: c.2.1.3 Alpha and beta proteins (a/b)    NAD(P)-binding Rossmann-fold domains    NAD(P)-binding Rossmann-fold domains    Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain    Glyceraldehyde-3-phosphate dehydrogenase (GAPDH)    Archaeon Methanothermus fervidus SCOP: c.2.1.3 Alpha and beta proteins (a/b)    NAD(P)-binding Rossmann-fold domains    NAD(P)-binding Rossmann-fold domains    Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain    Glyceraldehyde-3-phosphate dehydrogenase (GAPDH)    Archaeon Methanothermus fervidus SCOP: d.81.1.1 Alpha and beta proteins (a+b)    Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain    Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain    GAPDH-like    Glyceraldehyde-3-phosphate dehydrogenase (GAPDH)    Archaeon Methanothermus fervidus GO:  cytoplasm    glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) activity    glyceraldehyde-3-phosphate dehydrogenase activity    NAD binding    NADP binding    glycolysis

Image Source: PDB

Loops in ArchDB95 clusters

1cf2_O_119 - EH => SUBCLASS : 0.1.28
1cf2_O_50 - EH => SUBCLASS : 1.2.1
1cf2_O_50 - EH => SUBCLASS : 2.1.30
1cf2_O_26 - EH => SUBCLASS : 4.4.1
1cf2_O_104 - EH => SUBCLASS : 5.1.1
1cf2_O_219 - EH => SUBCLASS : 5.10.1
1cf2_O_278 - AR => SUBCLASS : 3.2.3
1cf2_O_305 - HH => SUBCLASS : 5.6.1
1cf2_O_305 - HH => SUBCLASS : 5.6.2
1cf2_O_90 - HE => SUBCLASS : 1.1.1
1cf2_O_38 - HE => SUBCLASS : 1.1.1
1cf2_O_90 - HE => SUBCLASS : 1.2.2
1cf2_O_38 - HE => SUBCLASS : 1.2.3
1cf2_O_72 - HE => SUBCLASS : 2.2.1
1cf2_O_11 - HE => SUBCLASS : 3.6.1
1cf2_O_11 - HE => SUBCLASS : 3.6.2
1cf2_O_233 - HE => SUBCLASS : 3.7.1
1cf2_O_233 - HE => SUBCLASS : 3.7.3
1cf2_O_286 - HA => SUBCLASS : 2.3.8
1cf2_O_286 - HA => SUBCLASS : 2.3.10

Loops in ArchDB-EC clusters

1cf2_O_305 - HH => SUBCLASS : 5.6.2

Loops not clustered in ArchDB

1cf2_O_158 - AR
1cf2_O_206 - AR
1cf2_O_158 - AR
1cf2_O_206 - AR
1cf2_O_278 - AR
1cf2_O_291 - EH
1cf2_O_246 - EH
1cf2_O_184 - EH
1cf2_O_134 - EH
1cf2_O_81 - EH
1cf2_O_70 - EH
1cf2_O_2 - EH
1cf2_O_286 - HA
1cf2_O_258 - HE
1cf2_O_194 - HE
1cf2_O_140 - HE
1cf2_O_113 - HE
1cf2_O_58 - HE
1cf2_O_122 - HE

1cf2 O - percentage of sequence identity: 100
1cf2 P - percentage of sequence identity: 100
1cf2 Q - percentage of sequence identity: 100
1cf2 R - percentage of sequence identity: 100