PDB: 1cza Compound: hexokinase type i Classification: TRANSFERASE Entry date in PDB: 2000-03-06 Resolution [Å]: 1.90 R-Factor: 0.213

CHAIN: N SWISS-PROT/TREMBL: P19367    KEYWORD: 3D-structure    Allosteric enzyme    Alternative splicing    ATP-binding    Glycolysis    Kinase    Membrane    Polymorphism    Repeat    Transferase    EC: 2.7.1.1 SCOP: c.55.1.3 Alpha and beta proteins (a/b)    Ribonuclease H-like motif    Actin-like ATPase domain    Hexokinase    Mammalian type I hexokinase    Human (Homo sapiens) SCOP: c.55.1.3 Alpha and beta proteins (a/b)    Ribonuclease H-like motif    Actin-like ATPase domain    Hexokinase    Mammalian type I hexokinase    Human (Homo sapiens) SCOP: c.55.1.3 Alpha and beta proteins (a/b)    Ribonuclease H-like motif    Actin-like ATPase domain    Hexokinase    Mammalian type I hexokinase    Human (Homo sapiens) SCOP: c.55.1.3 Alpha and beta proteins (a/b)    Ribonuclease H-like motif    Actin-like ATPase domain    Hexokinase    Mammalian type I hexokinase    Human (Homo sapiens) GO:  ATP binding    hexokinase activity    glycolysis

Image Source: PDB

Loops in ArchDB40 clusters

1cza_N_423 - HE => SUBCLASS : 4.1.2
1cza_N_871 - HE => SUBCLASS : 4.1.2
1cza_N_185 - HE => SUBCLASS : 6.26.1
1cza_N_633 - HE => SUBCLASS : 6.26.1
1cza_N_606 - HA => SUBCLASS : 2.2.1
1cza_N_78 - HA => SUBCLASS : 3.29.1
1cza_N_526 - HA => SUBCLASS : 3.29.1
1cza_N_158 - HA => SUBCLASS : 4.3.1
1cza_N_538 - HA => SUBCLASS : 5.17.1
1cza_N_158 - HA => SUBCLASS : 6.12.1
1cza_N_203 - EH => SUBCLASS : 1.1.2
1cza_N_552 - EH => SUBCLASS : 2.2.17
1cza_N_863 - HH => SUBCLASS : 1.1.41
1cza_N_415 - HH => SUBCLASS : 1.1.42
1cza_N_294 - HH => SUBCLASS : 1.1.48
1cza_N_481 - HH => SUBCLASS : 1.2.12
1cza_N_348 - HH => SUBCLASS : 5.7.1
1cza_N_797 - HH => SUBCLASS : 5.7.1

Loops in ArchDB95 clusters

1cza_N_203 - EH => SUBCLASS : 1.1.1
1cza_N_203 - EH => SUBCLASS : 1.1.5
1cza_N_552 - EH => SUBCLASS : 3.1.12
1cza_N_886 - EH => SUBCLASS : 4.68.1
1cza_N_254 - EH => SUBCLASS : 17.2.1
1cza_N_702 - EH => SUBCLASS : 17.2.1
1cza_N_150 - AR => SUBCLASS : 2.9.2
1cza_N_150 - AR => SUBCLASS : 3.23.1
1cza_N_481 - HH => SUBCLASS : 1.1.8
1cza_N_336 - HH => SUBCLASS : 1.1.48
1cza_N_481 - HH => SUBCLASS : 1.2.21
1cza_N_797 - HH => SUBCLASS : 5.1.1
1cza_N_348 - HH => SUBCLASS : 5.1.1
1cza_N_871 - HE => SUBCLASS : 3.4.2
1cza_N_209 - HE => SUBCLASS : 3.4.7
1cza_N_657 - HE => SUBCLASS : 3.4.11
1cza_N_871 - HE => SUBCLASS : 4.1.3
1cza_N_423 - HE => SUBCLASS : 4.1.3
1cza_N_633 - HE => SUBCLASS : 6.61.1
1cza_N_185 - HE => SUBCLASS : 6.61.1
1cza_N_606 - HA => SUBCLASS : 2.2.1
1cza_N_538 - HA => SUBCLASS : 2.3.13
1cza_N_672 - HA => SUBCLASS : 2.7.2
1cza_N_224 - HA => SUBCLASS : 2.7.2
1cza_N_158 - HA => SUBCLASS : 4.2.1
1cza_N_682 - HA => SUBCLASS : 12.9.1
1cza_N_234 - HA => SUBCLASS : 12.9.1

Loops in ArchDB-EC clusters

1cza_N_797 - HH => SUBCLASS : 5.8.1

Loops in ArchDB-KI clusters

1cza_N_150 - AR => SUBCLASS : 3.1.1
1cza_N_597 - AR => SUBCLASS : 3.1.1
1cza_N_64 - AR => SUBCLASS : 11.2.1
1cza_N_512 - AR => SUBCLASS : 11.2.1
1cza_N_613 - EH => SUBCLASS : 16.1.1
1cza_N_167 - EH => SUBCLASS : 16.1.1
1cza_N_254 - EH => SUBCLASS : 17.1.1
1cza_N_702 - EH => SUBCLASS : 17.1.1
1cza_N_158 - HA => SUBCLASS : 4.7.1
1cza_N_657 - HE => SUBCLASS : 3.4.1
1cza_N_423 - HE => SUBCLASS : 3.4.2
1cza_N_871 - HE => SUBCLASS : 3.4.2
1cza_N_348 - HH => SUBCLASS : 5.1.2
1cza_N_299 - HH => SUBCLASS : 19.1.1

Loops not clustered in ArchDB

1cza_N_64 - AR
1cza_N_512 - AR
1cza_N_597 - AR
1cza_N_64 - AR
1cza_N_150 - AR
1cza_N_512 - AR
1cza_N_597 - AR
1cza_N_103 - EH
1cza_N_167 - EH
1cza_N_406 - EH
1cza_N_854 - EH
1cza_N_650 - EH
1cza_N_438 - EH
1cza_N_613 - EH
1cza_N_606 - HA
1cza_N_78 - HA
1cza_N_90 - HA
1cza_N_158 - HA
1cza_N_224 - HA
1cza_N_234 - HA
1cza_N_538 - HA
1cza_N_672 - HA
1cza_N_526 - HA
1cza_N_90 - HA
1cza_N_682 - HA
1cza_N_33 - HE
1cza_N_123 - HE
1cza_N_365 - HE
1cza_N_501 - HE
1cza_N_571 - HE
1cza_N_813 - HE
1cza_N_784 - HH
1cza_N_17 - HH
1cza_N_116 - HH
1cza_N_276 - HH
1cza_N_299 - HH
1cza_N_449 - HH
1cza_N_564 - HH
1cza_N_724 - HH
1cza_N_750 - HH

Loops not clustered in ArchDB-KI

1cza_N_203 - EH
1cza_N_103 - EH
1cza_N_552 - EH
1cza_N_438 - EH
1cza_N_886 - EH
1cza_N_650 - EH
1cza_N_406 - EH
1cza_N_854 - EH
1cza_N_606 - HA
1cza_N_90 - HA
1cza_N_224 - HA
1cza_N_672 - HA
1cza_N_526 - HA
1cza_N_234 - HA
1cza_N_682 - HA
1cza_N_78 - HA
1cza_N_538 - HA
1cza_N_123 - HE
1cza_N_185 - HE
1cza_N_633 - HE
1cza_N_571 - HE
1cza_N_501 - HE
1cza_N_365 - HE
1cza_N_813 - HE
1cza_N_209 - HE
1cza_N_33 - HE
1cza_N_724 - HH
1cza_N_276 - HH
1cza_N_449 - HH
1cza_N_797 - HH
1cza_N_17 - HH
1cza_N_784 - HH
1cza_N_294 - HH
1cza_N_481 - HH
1cza_N_863 - HH
1cza_N_415 - HH
1cza_N_564 - HH
1cza_N_116 - HH
1cza_N_336 - HH
1cza_N_750 - HH

1bg3 A - percentage of sequence identity: 92
1bg3 B - percentage of sequence identity: 92
1dgk N - percentage of sequence identity: 99
1hkb A - percentage of sequence identity: 99
1hkb B - percentage of sequence identity: 99
1hkc A - percentage of sequence identity: 99
1qha A - percentage of sequence identity: 99
1qha B - percentage of sequence identity: 99