PDB: 1dls Compound: Dihydrofolate reductase (dhfr) mutant with leu 22 Classification: OXIDO-REDUCTASE Entry date in PDB: 1995-04-20 Resolution [Å]: 2.30 R-Factor: 0.156

CHAIN: - SWISS-PROT/TREMBL: P00374    KEYWORD: 3D-structure    NADP    One-carbon metabolism    Oxidoreductase    EC: 1.5.1.3 SCOP: c.71.1.1 Alpha and beta proteins (a/b)    Dihydrofolate reductases    Dihydrofolate reductases    Dihydrofolate reductases    Dihydrofolate reductases, eukaryotic type    Human (Homo sapiens) GO:  dihydrofolate reductase activity    glycine biosynthesis    nucleotide biosynthesis

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1kmv A - percentage of sequence identity: 99
8dfr - - percentage of sequence identity: 74