PDB: 1e1h Compound: botulinum neurotoxin type a light chain Classification: NEUROTOXIN Entry date in PDB: 2003-06-19 Resolution [Å]: 1.80 R-Factor: 0.196

CHAIN: A SWISS-PROT/TREMBL: Q45894    KEYWORD: 3D-structure    Hydrolase    Metalloprotease    Neurotoxin    Transmembrane    Zinc    3D-structure    Hydrolase    Metalloprotease    Neurotoxin    Transmembrane    Zinc    EC: 3.4.24.69 SCOP: d.92.1.7 Alpha and beta proteins (a+b)    Zincin-like    Metalloproteases ("zincins"), catalytic domain    Clostridium neurotoxins, catalytic domain    Botulinum neurotoxin    Clostridium botulinum, serotype A GO:  peptidase activity    pathogenesis    proteolysis and peptidolysis    CHAIN: B SWISS-PROT/TREMBL: Q45894    KEYWORD: 3D-structure    Hydrolase    Metalloprotease    Neurotoxin    Transmembrane    Zinc    EC: 3.4.24.69 SCOP: d.92.1.7 Alpha and beta proteins (a+b)    Zincin-like    Metalloproteases ("zincins"), catalytic domain    Clostridium neurotoxins, catalytic domain    Botulinum neurotoxin    Clostridium botulinum, serotype A GO:  peptidase activity    pathogenesis    proteolysis and peptidolysis    CHAIN: C SWISS-PROT/TREMBL: Q45894    KEYWORD: 3D-structure    Hydrolase    Metalloprotease    Neurotoxin    Transmembrane    Zinc    3D-structure    Hydrolase    Metalloprotease    Neurotoxin    Transmembrane    Zinc    EC: 3.4.24.69 SCOP: d.92.1.7 Alpha and beta proteins (a+b)    Zincin-like    Metalloproteases ("zincins"), catalytic domain    Clostridium neurotoxins, catalytic domain    Botulinum neurotoxin    Clostridium botulinum, serotype A GO:  peptidase activity    pathogenesis    proteolysis and peptidolysis    CHAIN: D SWISS-PROT/TREMBL: Q45894    KEYWORD: 3D-structure    Hydrolase    Metalloprotease    Neurotoxin    Transmembrane    Zinc    EC: 3.4.24.69 SCOP: d.92.1.7 Alpha and beta proteins (a+b)    Zincin-like    Metalloproteases ("zincins"), catalytic domain    Clostridium neurotoxins, catalytic domain    Botulinum neurotoxin    Clostridium botulinum, serotype A GO:  peptidase activity    pathogenesis    proteolysis and peptidolysis

Image Source: PDB

Loops in ArchDB-EC clusters

1e1h_A_80 - HH => SUBCLASS : 1.1.1

Loops not clustered in ArchDB

1e1h_A_183 - AR
1e1h_A_143 - AR
1e1h_A_150 - AR
1e1h_A_41 - EH
1e1h_B_330 - EH
1e1h_A_210 - EH
1e1h_A_194 - HA
1e1h_B_323 - HA
1e1h_A_163 - HA
1e1h_A_133 - HA
1e1h_A_32 - HA
1e1h_A_18 - HA
1e1h_B_373 - HA
1e1h_B_350 - HE
1e1h_B_309 - HE
1e1h_A_101 - HE
1e1h_B_334 - HH
1e1h_B_275 - HH
1e1h_B_259 - HH

1e1h A - percentage of sequence identity: 100
1e1h C - percentage of sequence identity: 100
1gv4 A - percentage of sequence identity: 97
1gv4 B - percentage of sequence identity: 97
1ik6 A - percentage of sequence identity: 92
1n0h A - percentage of sequence identity: 63
1n0h B - percentage of sequence identity: 63
1nkt A - percentage of sequence identity: 100
1nkt B - percentage of sequence identity: 100
1nl3 A - percentage of sequence identity: 100
1nl3 B - percentage of sequence identity: 100
1ou5 A - percentage of sequence identity: 90
1ou5 B - percentage of sequence identity: 90
1t9a A - percentage of sequence identity: 63
1t9a B - percentage of sequence identity: 63
1t9b A - percentage of sequence identity: 63
1t9b B - percentage of sequence identity: 63
1t9c A - percentage of sequence identity: 63
1t9c B - percentage of sequence identity: 63
1t9d A - percentage of sequence identity: 63
1t9d B - percentage of sequence identity: 63
1t9d C - percentage of sequence identity: 63
1t9d D - percentage of sequence identity: 63
1u34 A - percentage of sequence identity: 100
1xtf A - percentage of sequence identity: 97
1xtf B - percentage of sequence identity: 97
1xtg A - percentage of sequence identity: 97
1z9m A - percentage of sequence identity: 100
1z9m B - percentage of sequence identity: 100
3bta A - percentage of sequence identity: 97