PDB: 1ee4 Compound: karyopherin alpha Classification: TRANSPORT PROTEIN Entry date in PDB: 2000-03-29 Resolution [Å]: 2.10 R-Factor: 0.246

CHAIN: A SWISS-PROT/TREMBL: Q02821    KEYWORD: 3D-structure    Nuclear protein    Protein transport    Repeat    Transport    SCOP: a.118.1.1 All alpha proteins    alpha-alpha superhelix    ARM repeat    Armadillo repeat    Karyopherin alpha    Baker's yeast (Saccharomyces cerevisiae) GO:  binding    protein transporter activity    intracellular protein transport    protein-nucleus import    CHAIN: B SWISS-PROT/TREMBL: Q02821    KEYWORD: 3D-structure    Nuclear protein    Protein transport    Repeat    Transport    SCOP: a.118.1.1 All alpha proteins    alpha-alpha superhelix    ARM repeat    Armadillo repeat    Karyopherin alpha    Baker's yeast (Saccharomyces cerevisiae) GO:  binding    protein transporter activity    intracellular protein transport    protein-nucleus import    CHAIN: C SWISS-PROT/TREMBL: P01106    KEYWORD: 3D-structure    Activator    DNA-binding    Glycoprotein    Nuclear protein    Phosphorylation    Polymorphism    Proto-oncogene    Transcription regulation    GO:  nucleus    transcription factor activity    transcription regulator activity    regulation of transcription    regulation of transcription, DNA-dependent    CHAIN: D SWISS-PROT/TREMBL: P01106    KEYWORD: 3D-structure    Activator    DNA-binding    Glycoprotein    Nuclear protein    Phosphorylation    Polymorphism    Proto-oncogene    Transcription regulation    GO:  nucleus    transcription factor activity    transcription regulator activity    regulation of transcription    regulation of transcription, DNA-dependent    CHAIN: E SWISS-PROT/TREMBL: P01106    KEYWORD: 3D-structure    Activator    DNA-binding    Glycoprotein    Nuclear protein    Phosphorylation    Polymorphism    Proto-oncogene    Transcription regulation    GO:  nucleus    transcription factor activity    transcription regulator activity    regulation of transcription    regulation of transcription, DNA-dependent    CHAIN: F SWISS-PROT/TREMBL: P01106    KEYWORD: 3D-structure    Activator    DNA-binding    Glycoprotein    Nuclear protein    Phosphorylation    Polymorphism    Proto-oncogene    Transcription regulation    GO:  nucleus    transcription factor activity    transcription regulator activity    regulation of transcription    regulation of transcription, DNA-dependent

Image Source: PDB

Loops in ArchDB40 clusters

1ee4_A_331 - HH => SUBCLASS : 1.3.1
1ee4_A_289 - HH => SUBCLASS : 1.3.1
1ee4_A_163 - HH => SUBCLASS : 1.3.1
1ee4_A_472 - HH => SUBCLASS : 1.3.1
1ee4_A_205 - HH => SUBCLASS : 1.3.3
1ee4_A_373 - HH => SUBCLASS : 1.3.3
1ee4_A_123 - HH => SUBCLASS : 1.3.3
1ee4_A_418 - HH => SUBCLASS : 1.3.4
1ee4_A_373 - HH => SUBCLASS : 1.3.14
1ee4_A_418 - HH => SUBCLASS : 1.3.16
1ee4_A_418 - HH => SUBCLASS : 1.3.18
1ee4_A_174 - HH => SUBCLASS : 2.1.18
1ee4_A_385 - HH => SUBCLASS : 2.1.18
1ee4_A_217 - HH => SUBCLASS : 2.4.5
1ee4_A_300 - HH => SUBCLASS : 3.4.1
1ee4_A_482 - HH => SUBCLASS : 3.4.1
1ee4_A_342 - HH => SUBCLASS : 3.4.1
1ee4_A_259 - HH => SUBCLASS : 3.4.1
1ee4_A_430 - HH => SUBCLASS : 3.4.1
1ee4_A_89 - HH => SUBCLASS : 3.4.2
1ee4_A_89 - HH => SUBCLASS : 3.4.3

Loops in ArchDB95 clusters

1ee4_A_472 - HH => SUBCLASS : 1.3.1
1ee4_A_289 - HH => SUBCLASS : 1.3.1
1ee4_A_373 - HH => SUBCLASS : 1.3.4
1ee4_A_205 - HH => SUBCLASS : 1.3.4
1ee4_A_331 - HH => SUBCLASS : 1.3.4
1ee4_A_123 - HH => SUBCLASS : 1.3.4
1ee4_A_418 - HH => SUBCLASS : 1.3.4
1ee4_A_331 - HH => SUBCLASS : 1.3.5
1ee4_A_163 - HH => SUBCLASS : 1.3.20
1ee4_A_313 - HH => SUBCLASS : 2.1.6
1ee4_A_145 - HH => SUBCLASS : 2.1.6
1ee4_A_355 - HH => SUBCLASS : 2.1.6
1ee4_A_385 - HH => SUBCLASS : 2.1.9
1ee4_A_217 - HH => SUBCLASS : 2.5.7
1ee4_A_300 - HH => SUBCLASS : 3.3.1
1ee4_A_482 - HH => SUBCLASS : 3.3.1
1ee4_A_89 - HH => SUBCLASS : 3.3.1
1ee4_A_259 - HH => SUBCLASS : 3.3.1
1ee4_A_430 - HH => SUBCLASS : 3.3.1
1ee4_A_342 - HH => SUBCLASS : 3.3.1
1ee4_A_430 - HH => SUBCLASS : 3.3.4
1ee4_A_132 - HH => SUBCLASS : 5.3.1

Loops not clustered in ArchDB

1ee4_A_101 - HH
1ee4_A_187 - HH
1ee4_A_229 - HH
1ee4_A_252 - HH
1ee4_A_271 - HH
1ee4_A_397 - HH
1ee4_A_442 - HH

1bk5 A - percentage of sequence identity: 99
1bk5 B - percentage of sequence identity: 99
1bk6 A - percentage of sequence identity: 99
1bk6 B - percentage of sequence identity: 99
1ee4 A - percentage of sequence identity: 100
1ee4 B - percentage of sequence identity: 100
1ee5 A - percentage of sequence identity: 100
1un0 A - percentage of sequence identity: 100
1un0 B - percentage of sequence identity: 100
1wa5 B - percentage of sequence identity: 99
2c1t A - percentage of sequence identity: 100
2c1t B - percentage of sequence identity: 100