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Information on 1eer
PDB: 1eer
Compound: erythropoietin
Classification: COMPLEX (CYTOKINE/RECEPTOR)
Entry date in PDB: 1999-10-01
Resolution [Å]: 1.90
R-Factor: 0.242


CHAIN: A
SWISS-PROT/TREMBL: P01588
   KEYWORD: 3D-structure    Erythrocyte maturation    Glycoprotein    Hormone    Pharmaceutical    Polymorphism    Signal   
SCOP: a.26.1.2 All alpha proteins    4-helical cytokines    4-helical cytokines    Short-chain cytokines    Erythropoietin    Human (Homo sapiens)
GO:  extracellular region    erythropoietin receptor binding    hormone activity   


CHAIN: B
SWISS-PROT/TREMBL: P19235
   KEYWORD: 3D-structure    Alternative splicing    Glycoprotein    Phosphorylation    Receptor    Signal    Transmembrane    Ubl conjugation   
SCOP: b.1.2.1 All beta proteins    Immunoglobulin-like beta-sandwich    Fibronectin type III    Fibronectin type III    Erythropoietin (EPO) receptor    Human (Homo sapiens)
SCOP: b.1.2.1 All beta proteins    Immunoglobulin-like beta-sandwich    Fibronectin type III    Fibronectin type III    Erythropoietin (EPO) receptor    Human (Homo sapiens)
GO:  integral to membrane    membrane    hematopoietin/interferon-class (D200-domain) cytokine receptor activity    transmembrane receptor activity   


CHAIN: C
SWISS-PROT/TREMBL: P19235
   KEYWORD: 3D-structure    Alternative splicing    Glycoprotein    Phosphorylation    Receptor    Signal    Transmembrane    Ubl conjugation   
SCOP: b.1.2.1 All beta proteins    Immunoglobulin-like beta-sandwich    Fibronectin type III    Fibronectin type III    Erythropoietin (EPO) receptor    Human (Homo sapiens)
SCOP: b.1.2.1 All beta proteins    Immunoglobulin-like beta-sandwich    Fibronectin type III    Fibronectin type III    Erythropoietin (EPO) receptor    Human (Homo sapiens)
GO:  integral to membrane    membrane    hematopoietin/interferon-class (D200-domain) cytokine receptor activity    transmembrane receptor activity   
1eer Image
Image Source: PDB

Stored Loops of 1eer

Loops in ArchDB40 clusters

1eer_A_91 - HH => SUBCLASS : 1.3.1
1eer_A_138 - HH => SUBCLASS : 1.10.1
1eer_A_48 - HH => SUBCLASS : 2.1.36

Loops in ArchDB95 clusters

1eer_A_91 - HH => SUBCLASS : 1.3.1
1eer_A_138 - HH => SUBCLASS : 1.7.1
1eer_A_48 - HH => SUBCLASS : 2.3.20

Loops not clustered in ArchDB

1eer_A_34 - EH
1eer_A_133 - EH
1eer_A_9 - HE
1eer_A_114 - HE
1eer_A_56 - HH

Homologous structures to 1eer classified in ArchDB

1buy A - percentage of sequence identity: 98
1cn4 C - percentage of sequence identity: 98
null nu - percentage of sequence identity: 0