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Information on 1efn
PDB: 1efn
Compound: fyn tyrosine kinase
Classification: COMPLEX (SH3 DOMAIN/VIRAL ENHANCER)
Entry date in PDB: 1997-01-11
Resolution [Å]: 2.50
R-Factor: 0.215


CHAIN: A
SWISS-PROT/TREMBL: P06241
   KEYWORD: 3D-structure    ATP-binding    Lipoprotein    Myristate    Palmitate    Phosphorylation    Polymorphism    Proto-oncogene    SH2 domain    SH3 domain    Transferase    Tyrosine-protein kinase   
EC: 2.7.1.112
SCOP: b.34.2.1 All beta proteins    SH3-like barrel    SH3-domain    SH3-domain    Fyn proto-oncogene tyrosine kinase, SH3 domain    Human (Homo sapiens)
GO:  ATP binding    protein kinase activity    protein-tyrosine kinase activity    intracellular signaling cascade    protein amino acid phosphorylation   


CHAIN: B
SWISS-PROT/TREMBL: P03406
   KEYWORD: 3D-structure    AIDS    GTP-binding    Lipoprotein    Myristate    Phosphorylation   
SCOP: d.102.1.1 Alpha and beta proteins (a+b)    Regulatory factor Nef    Regulatory factor Nef    Regulatory factor Nef    Regulatory factor Nef    Human immunodeficiency virus type 1
GO:  GTP binding   


CHAIN: C
SWISS-PROT/TREMBL: P06241
   KEYWORD: 3D-structure    ATP-binding    Lipoprotein    Myristate    Palmitate    Phosphorylation    Polymorphism    Proto-oncogene    SH2 domain    SH3 domain    Transferase    Tyrosine-protein kinase   
EC: 2.7.1.112
SCOP: b.34.2.1 All beta proteins    SH3-like barrel    SH3-domain    SH3-domain    Fyn proto-oncogene tyrosine kinase, SH3 domain    Human (Homo sapiens)
GO:  ATP binding    protein kinase activity    protein-tyrosine kinase activity    intracellular signaling cascade    protein amino acid phosphorylation   


CHAIN: D
SWISS-PROT/TREMBL: P03406
   KEYWORD: 3D-structure    AIDS    GTP-binding    Lipoprotein    Myristate    Phosphorylation   
SCOP: d.102.1.1 Alpha and beta proteins (a+b)    Regulatory factor Nef    Regulatory factor Nef    Regulatory factor Nef    Regulatory factor Nef    Human immunodeficiency virus type 1
GO:  GTP binding   
1efn Image
Image Source: PDB

Stored Loops of 1efn

Loops in ArchDB95 clusters

1efn_A_119 - HA => SUBCLASS : 4.1.1

Loops not clustered in ArchDB

1efn_B_181 - EH
1efn_B_143 - HA
1efn_A_86 - HA
1efn_A_108 - HA
1efn_A_129 - HA
1efn_B_104 - HE
1efn_B_81 - HH

Homologous structures to 1efn classified in ArchDB

1a0n B - percentage of sequence identity: 98
1ad5 A - percentage of sequence identity: 63
1ad5 B - percentage of sequence identity: 63
1avz C - percentage of sequence identity: 98
1azg B - percentage of sequence identity: 98
1bu1 A - percentage of sequence identity: 63
1bu1 B - percentage of sequence identity: 63
1bu1 C - percentage of sequence identity: 63
1bu1 D - percentage of sequence identity: 63
1bu1 E - percentage of sequence identity: 63
1bu1 F - percentage of sequence identity: 63
1efn A - percentage of sequence identity: 100
1efn C - percentage of sequence identity: 100
1fmk - - percentage of sequence identity: 75
1fyn A - percentage of sequence identity: 98
1g83 A - percentage of sequence identity: 98
1g83 B - percentage of sequence identity: 98
1ksw A - percentage of sequence identity: 75
1m27 C - percentage of sequence identity: 98
1nlo C - percentage of sequence identity: 77
1nlp C - percentage of sequence identity: 77
1nyf - - percentage of sequence identity: 98
1nyg - - percentage of sequence identity: 98
1prl C - percentage of sequence identity: 77
1prm C - percentage of sequence identity: 77
1qcf A - percentage of sequence identity: 63
1qwe A - percentage of sequence identity: 77
1qwf A - percentage of sequence identity: 77
1rlp C - percentage of sequence identity: 77
1rlq C - percentage of sequence identity: 77
1shf A - percentage of sequence identity: 98
1shf B - percentage of sequence identity: 98
1srl - - percentage of sequence identity: 77
1srm - - percentage of sequence identity: 77
1y57 A - percentage of sequence identity: 75
1zbj A - percentage of sequence identity: 98
2hck A - percentage of sequence identity: 63
2hck B - percentage of sequence identity: 63
2ptk - - percentage of sequence identity: 77
2src - - percentage of sequence identity: 75
4hck - - percentage of sequence identity: 63
5hck - - percentage of sequence identity: 63
null nu - percentage of sequence identity: 0