PDB: 1egd Compound: medium chain acyl-coa dehydrogenase Classification: ELECTRON TRANSFER Entry date in PDB: 1997-06-16 Resolution [Å]: 2.40 R-Factor: 0.208

CHAIN: A SWISS-PROT/TREMBL: P11310    KEYWORD: 3D-structure    Disease mutation    FAD    Fatty acid metabolism    Flavoprotein    Mitochondrion    Oxidoreductase    Transit peptide    EC: 1.3.99.3 SCOP: a.29.3.1 All alpha proteins    Bromodomain-like    Acyl-CoA dehydrogenase C-terminal domain-like    Medium chain acyl-CoA dehydrogenase-like, C-terminal domain    Medium chain acyl-CoA dehydrogenase, C-domain    Human (Homo sapiens) SCOP: e.6.1.1 Multi-domain proteins (alpha and beta)    Acyl-CoA dehydrogenase NM domain-like    Acyl-CoA dehydrogenase NM domain-like    Medium chain acyl-CoA dehydrogenase, NM (N-terminal and middle) domains    Medium chain acyl-CoA dehydrogenase, NM domains    Human (Homo sapiens) GO:  acyl-CoA dehydrogenase activity    oxidoreductase activity    electron transport    CHAIN: B SWISS-PROT/TREMBL: P11310    KEYWORD: 3D-structure    Disease mutation    FAD    Fatty acid metabolism    Flavoprotein    Mitochondrion    Oxidoreductase    Transit peptide    EC: 1.3.99.3 SCOP: a.29.3.1 All alpha proteins    Bromodomain-like    Acyl-CoA dehydrogenase C-terminal domain-like    Medium chain acyl-CoA dehydrogenase-like, C-terminal domain    Medium chain acyl-CoA dehydrogenase, C-domain    Human (Homo sapiens) SCOP: e.6.1.1 Multi-domain proteins (alpha and beta)    Acyl-CoA dehydrogenase NM domain-like    Acyl-CoA dehydrogenase NM domain-like    Medium chain acyl-CoA dehydrogenase, NM (N-terminal and middle) domains    Medium chain acyl-CoA dehydrogenase, NM domains    Human (Homo sapiens) GO:  acyl-CoA dehydrogenase activity    oxidoreductase activity    electron transport    CHAIN: C SWISS-PROT/TREMBL: P11310    KEYWORD: 3D-structure    Disease mutation    FAD    Fatty acid metabolism    Flavoprotein    Mitochondrion    Oxidoreductase    Transit peptide    EC: 1.3.99.3 SCOP: a.29.3.1 All alpha proteins    Bromodomain-like    Acyl-CoA dehydrogenase C-terminal domain-like    Medium chain acyl-CoA dehydrogenase-like, C-terminal domain    Medium chain acyl-CoA dehydrogenase, C-domain    Human (Homo sapiens) SCOP: e.6.1.1 Multi-domain proteins (alpha and beta)    Acyl-CoA dehydrogenase NM domain-like    Acyl-CoA dehydrogenase NM domain-like    Medium chain acyl-CoA dehydrogenase, NM (N-terminal and middle) domains    Medium chain acyl-CoA dehydrogenase, NM domains    Human (Homo sapiens) GO:  acyl-CoA dehydrogenase activity    oxidoreductase activity    electron transport    CHAIN: D SWISS-PROT/TREMBL: P11310    KEYWORD: 3D-structure    Disease mutation    FAD    Fatty acid metabolism    Flavoprotein    Mitochondrion    Oxidoreductase    Transit peptide    EC: 1.3.99.3 SCOP: a.29.3.1 All alpha proteins    Bromodomain-like    Acyl-CoA dehydrogenase C-terminal domain-like    Medium chain acyl-CoA dehydrogenase-like, C-terminal domain    Medium chain acyl-CoA dehydrogenase, C-domain    Human (Homo sapiens) SCOP: e.6.1.1 Multi-domain proteins (alpha and beta)    Acyl-CoA dehydrogenase NM domain-like    Acyl-CoA dehydrogenase NM domain-like    Medium chain acyl-CoA dehydrogenase, NM (N-terminal and middle) domains    Medium chain acyl-CoA dehydrogenase, NM domains    Human (Homo sapiens) GO:  acyl-CoA dehydrogenase activity    oxidoreductase activity    electron transport

Image Source: PDB

Loops in ArchDB95 clusters

1egd_A_286 - EH => SUBCLASS : 4.16.2
1egd_A_194 - AR => SUBCLASS : 5.63.1
1egd_A_131 - AR => SUBCLASS : 15.1.1
1egd_A_362 - HH => SUBCLASS : 4.34.1
1egd_A_326 - HH => SUBCLASS : 9.10.1
1egd_A_150 - HA => SUBCLASS : 2.3.8

Loops in ArchDB-EC clusters

1egd_A_50 - HH => SUBCLASS : 17.2.1

Loops not clustered in ArchDB

1egd_A_157 - AR
1egd_A_131 - AR
1egd_A_194 - AR
1egd_A_157 - AR
1egd_A_222 - EH
1egd_A_175 - HA
1egd_A_206 - HA
1egd_A_282 - HA
1egd_A_206 - HA
1egd_A_150 - HA
1egd_A_175 - HA
1egd_A_282 - HA
1egd_A_244 - HE
1egd_A_114 - HE
1egd_A_292 - HH
1egd_A_106 - HH
1egd_A_92 - HH
1egd_A_77 - HH
1egd_A_36 - HH
1egd_A_18 - HH

1egc A - percentage of sequence identity: 100
1egc B - percentage of sequence identity: 100
1egc C - percentage of sequence identity: 100
1egc D - percentage of sequence identity: 100
1egd A - percentage of sequence identity: 100
1egd B - percentage of sequence identity: 100
1egd C - percentage of sequence identity: 100
1egd D - percentage of sequence identity: 100
1ege A - percentage of sequence identity: 99
1ege B - percentage of sequence identity: 99
1ege C - percentage of sequence identity: 99
1ege D - percentage of sequence identity: 99
1t9g A - percentage of sequence identity: 99
1t9g B - percentage of sequence identity: 99
1t9g C - percentage of sequence identity: 99
1t9g D - percentage of sequence identity: 99
1udy A - percentage of sequence identity: 88
1udy B - percentage of sequence identity: 88
1udy C - percentage of sequence identity: 88
1udy D - percentage of sequence identity: 88
2a1t A - percentage of sequence identity: 99
2a1t B - percentage of sequence identity: 99
2a1t C - percentage of sequence identity: 99
2a1t D - percentage of sequence identity: 99
3mdd A - percentage of sequence identity: 88
3mdd B - percentage of sequence identity: 88
3mde A - percentage of sequence identity: 88
3mde B - percentage of sequence identity: 88