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Information on 1f28
PDB: 1f28
Compound: thymidylate synthase
Classification: TRANSFERASE
Entry date in PDB: 2001-06-06
Resolution [Å]: 1.90
R-Factor: 0.217


CHAIN: A
SWISS-PROT/TREMBL: P13100
   KEYWORD: 3D-structure    Methyltransferase    Nucleotide biosynthesis    Transferase   
EC: 2.1.1.45
SCOP: d.117.1.1 Alpha and beta proteins (a+b)    Thymidylate synthase/dCMP hydroxymethylase    Thymidylate synthase/dCMP hydroxymethylase    Thymidylate synthase/dCMP hydroxymethylase    Thymidylate synthase    Pneumocystis carinii
GO:  thymidylate synthase activity    dTMP biosynthesis   


CHAIN: B
SWISS-PROT/TREMBL: P13100
   KEYWORD: 3D-structure    Methyltransferase    Nucleotide biosynthesis    Transferase   
EC: 2.1.1.45
SCOP: d.117.1.1 Alpha and beta proteins (a+b)    Thymidylate synthase/dCMP hydroxymethylase    Thymidylate synthase/dCMP hydroxymethylase    Thymidylate synthase/dCMP hydroxymethylase    Thymidylate synthase    Pneumocystis carinii
GO:  thymidylate synthase activity    dTMP biosynthesis   


CHAIN: C
SWISS-PROT/TREMBL: P13100
   KEYWORD: 3D-structure    Methyltransferase    Nucleotide biosynthesis    Transferase   
EC: 2.1.1.45
SCOP: d.117.1.1 Alpha and beta proteins (a+b)    Thymidylate synthase/dCMP hydroxymethylase    Thymidylate synthase/dCMP hydroxymethylase    Thymidylate synthase/dCMP hydroxymethylase    Thymidylate synthase    Pneumocystis carinii
GO:  thymidylate synthase activity    dTMP biosynthesis   


CHAIN: D
SWISS-PROT/TREMBL: P13100
   KEYWORD: 3D-structure    Methyltransferase    Nucleotide biosynthesis    Transferase   
EC: 2.1.1.45
SCOP: d.117.1.1 Alpha and beta proteins (a+b)    Thymidylate synthase/dCMP hydroxymethylase    Thymidylate synthase/dCMP hydroxymethylase    Thymidylate synthase/dCMP hydroxymethylase    Thymidylate synthase    Pneumocystis carinii
GO:  thymidylate synthase activity    dTMP biosynthesis   
1f28 Image
Image Source: PDB

Stored Loops of 1f28

Loops in ArchDB95 clusters

1f28_A_191 - EH => SUBCLASS : 1.2.10
1f28_A_30 - AR => SUBCLASS : 4.22.1
1f28_A_88 - HH => SUBCLASS : 1.1.6
1f28_A_59 - HH => SUBCLASS : 4.5.1
1f28_A_113 - HH => SUBCLASS : 18.2.1
1f28_A_4 - HE => SUBCLASS : 0.1.1
1f28_A_206 - HE => SUBCLASS : 1.2.17
1f28_A_21 - HA => SUBCLASS : 3.1.1
1f28_A_156 - HA => SUBCLASS : 15.1.1

Loops in ArchDB-EC clusters

1f28_A_113 - HH => SUBCLASS : 18.1.1

Loops not clustered in ArchDB

1f28_A_30 - AR
1f28_A_40 - EH
1f28_A_228 - EH
1f28_A_174 - HA
1f28_A_156 - HA
1f28_A_21 - HA
1f28_A_262 - HA
1f28_A_174 - HA
1f28_A_262 - HA
1f28_A_243 - HE
1f28_A_138 - HE
1f28_A_93 - HH
1f28_A_76 - HH

Homologous structures to 1f28 classified in ArchDB

1ci7 A - percentage of sequence identity: 100
1ci7 B - percentage of sequence identity: 100
1f28 A - percentage of sequence identity: 100
1f28 B - percentage of sequence identity: 100
1f28 C - percentage of sequence identity: 100
1f28 D - percentage of sequence identity: 100
1hvy A - percentage of sequence identity: 61
1hvy B - percentage of sequence identity: 61
1hvy C - percentage of sequence identity: 61
1hvy D - percentage of sequence identity: 61
1hw3 A - percentage of sequence identity: 61
1hw4 A - percentage of sequence identity: 61
1hzw A - percentage of sequence identity: 61
1hzw B - percentage of sequence identity: 61
1i00 A - percentage of sequence identity: 61
1i00 B - percentage of sequence identity: 61
1ju6 A - percentage of sequence identity: 61
1ju6 B - percentage of sequence identity: 61
1ju6 C - percentage of sequence identity: 61
1ju6 D - percentage of sequence identity: 61
1juj A - percentage of sequence identity: 61
1juj B - percentage of sequence identity: 61
1juj C - percentage of sequence identity: 61
1juj D - percentage of sequence identity: 61
1rts A - percentage of sequence identity: 61
1rts B - percentage of sequence identity: 61
1ypv A - percentage of sequence identity: 61
2aaz A - percentage of sequence identity: 60
2aaz B - percentage of sequence identity: 60
2aaz C - percentage of sequence identity: 60
2aaz D - percentage of sequence identity: 60
2aaz E - percentage of sequence identity: 60
2aaz F - percentage of sequence identity: 60
2aaz G - percentage of sequence identity: 60
2aaz H - percentage of sequence identity: 60
2aaz I - percentage of sequence identity: 60
2aaz J - percentage of sequence identity: 60
2aaz K - percentage of sequence identity: 60
2aaz L - percentage of sequence identity: 60
2aaz M - percentage of sequence identity: 60
2aaz N - percentage of sequence identity: 60
2aaz O - percentage of sequence identity: 60
2aaz P - percentage of sequence identity: 60
2tsr A - percentage of sequence identity: 61
2tsr B - percentage of sequence identity: 61
2tsr C - percentage of sequence identity: 61
2tsr D - percentage of sequence identity: 61