PDB: 1fbl Compound: fibroblast (interstitial) collagenase (mmp-1) Classification: METALLOPROTEASE Entry date in PDB: 1996-01-29 Resolution [Å]: 2.50 R-Factor: 0.217

CHAIN: - SWISS-PROT/TREMBL: P21692    KEYWORD: 3D-structure    Autocatalytic cleavage    Calcium-binding    Collagen degradation    Extracellular matrix    Glycoprotein    Hydrolase    Metal-binding    Metalloprotease    Signal    Zinc    Zymogen    EC: 3.4.24.7 SCOP: b.66.1.1 All beta proteins    4-bladed beta-propeller    Hemopexin-like domain    Hemopexin-like domain    Collagenase, C-terminal domain    Pig (Sus scrofa) SCOP: d.92.1.11 Alpha and beta proteins (a+b)    Zincin-like    Metalloproteases ("zincins"), catalytic domain    Matrix metalloproteases, catalytic domain    Fibroblast collagenase (MMP-1)    Pig (Sus scrofa) GO:  extracellular matrix (sensu Metazoa)    metalloendopeptidase activity    metallopeptidase activity    zinc ion binding    proteolysis and peptidolysis

Image Source: PDB

Loops in ArchDB40 clusters

1fbl_*_347 - HA => SUBCLASS : 2.1.1
1fbl_*_286 - HA => SUBCLASS : 2.1.1
1fbl_*_435 - HA => SUBCLASS : 2.3.1
1fbl_*_388 - HA => SUBCLASS : 2.3.1
1fbl_*_330 - HA => SUBCLASS : 4.1.1
1fbl_*_379 - HA => SUBCLASS : 4.1.1
1fbl_*_396 - HA => SUBCLASS : 4.1.1
1fbl_*_443 - HA => SUBCLASS : 4.1.2
1fbl_*_413 - EH => SUBCLASS : 0.1.8
1fbl_*_113 - EH => SUBCLASS : 6.2.1
1fbl_*_148 - AR => SUBCLASS : 6.14.1

Loops in ArchDB95 clusters

1fbl_*_413 - EH => SUBCLASS : 0.1.6
1fbl_*_113 - EH => SUBCLASS : 5.3.1
1fbl_*_195 - EH => SUBCLASS : 13.8.1
1fbl_*_148 - AR => SUBCLASS : 6.7.1
1fbl_*_286 - HA => SUBCLASS : 2.1.1
1fbl_*_347 - HA => SUBCLASS : 2.1.1
1fbl_*_388 - HA => SUBCLASS : 2.3.1
1fbl_*_435 - HA => SUBCLASS : 2.3.1
1fbl_*_396 - HA => SUBCLASS : 4.1.1
1fbl_*_330 - HA => SUBCLASS : 4.1.1
1fbl_*_379 - HA => SUBCLASS : 4.1.1
1fbl_*_443 - HA => SUBCLASS : 4.1.2
1fbl_*_182 - HA => SUBCLASS : 9.3.1

Loops in ArchDB-EC clusters

1fbl_*_127 - HE => SUBCLASS : 3.8.1

Loops not clustered in ArchDB

1fbl_*_148 - AR
1fbl_*_101 - AR
1fbl_*_355 - AR
1fbl_*_406 - AR
1fbl_*_101 - AR
1fbl_*_159 - AR
1fbl_*_355 - AR
1fbl_*_406 - AR
1fbl_*_159 - AR
1fbl_*_226 - EH
1fbl_*_313 - EH
1fbl_*_362 - EH
1fbl_*_293 - HA
1fbl_*_330 - HA
1fbl_*_339 - HA
1fbl_*_347 - HA
1fbl_*_379 - HA
1fbl_*_388 - HA
1fbl_*_396 - HA
1fbl_*_428 - HA
1fbl_*_435 - HA
1fbl_*_301 - HA
1fbl_*_293 - HA
1fbl_*_301 - HA
1fbl_*_339 - HA
1fbl_*_428 - HA
1fbl_*_182 - HA
1fbl_*_286 - HA
1fbl_*_443 - HA
1fbl_*_250 - HE
1fbl_*_317 - HE
1fbl_*_212 - HE
1fbl_*_364 - HE
1fbl_*_415 - HE

1a85 A - percentage of sequence identity: 67
1a86 A - percentage of sequence identity: 67
1ayk - - percentage of sequence identity: 90
1b8y A - percentage of sequence identity: 60
1bzs A - percentage of sequence identity: 68
1c8t A - percentage of sequence identity: 60
1c8t B - percentage of sequence identity: 60
1caq A - percentage of sequence identity: 60
1cge - - percentage of sequence identity: 89
1cgf A - percentage of sequence identity: 90
1cgf B - percentage of sequence identity: 90
1cgl B - percentage of sequence identity: 88
1ciz A - percentage of sequence identity: 60
1cxv B - percentage of sequence identity: 60
1g4k A - percentage of sequence identity: 60
1g4k B - percentage of sequence identity: 60
1g4k C - percentage of sequence identity: 60
1hfs - - percentage of sequence identity: 61
1i73 A - percentage of sequence identity: 68
1jan A - percentage of sequence identity: 68
1jao A - percentage of sequence identity: 68
1jap A - percentage of sequence identity: 68
1jaq A - percentage of sequence identity: 68
1jh1 A - percentage of sequence identity: 67
1jiz A - percentage of sequence identity: 60
1jiz B - percentage of sequence identity: 60
1jj9 A - percentage of sequence identity: 68
1kbc A - percentage of sequence identity: 68
1kbc B - percentage of sequence identity: 68
1mmb - - percentage of sequence identity: 68
1mnc - - percentage of sequence identity: 67
1oo9 A - percentage of sequence identity: 60
1qia A - percentage of sequence identity: 61
1qia B - percentage of sequence identity: 61
1qia C - percentage of sequence identity: 61
1qia D - percentage of sequence identity: 61
1qic A - percentage of sequence identity: 61
1qic B - percentage of sequence identity: 61
1qic C - percentage of sequence identity: 61
1qic D - percentage of sequence identity: 61
1su3 A - percentage of sequence identity: 87
1su3 B - percentage of sequence identity: 87
1usn - - percentage of sequence identity: 60
1zp5 A - percentage of sequence identity: 68
2ayk - - percentage of sequence identity: 90
2tcl - - percentage of sequence identity: 90
2usn - - percentage of sequence identity: 60
3ayk A - percentage of sequence identity: 90
3usn - - percentage of sequence identity: 60
4ayk A - percentage of sequence identity: 90
966c - - percentage of sequence identity: 90