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Information on 1flt
PDB: 1flt
Compound: vascular endothelial growth factor
Classification: COMPLEX (GROWTH FACTOR/TRANSFERASE)
Entry date in PDB: 1999-01-13
Resolution [Å]: 1.70
R-Factor: 0.198


CHAIN: X
SWISS-PROT/TREMBL: P17948
   KEYWORD: 3D-structure    Alternative splicing    Angiogenesis    ATP-binding    Glycoprotein    Immunoglobulin domain    Kinase    Phosphorylation    Receptor    Repeat    Signal    Transferase    Transmembrane    Tyrosine-protein kinase   
EC: 2.7.1.112
SCOP: b.1.1.4 All beta proteins    Immunoglobulin-like beta-sandwich    Immunoglobulin    I set domains    Second domain of the Flt-1 receptor    Human (Homo sapiens)
GO:  membrane    ATP binding    protein kinase activity    protein-tyrosine kinase activity    transmembrane receptor protein tyrosine kinase activity    vascular endothelial growth factor receptor activity    protein amino acid phosphorylation    transmembrane receptor protein tyrosine kinase signaling pathway   


CHAIN: Y
SWISS-PROT/TREMBL: P17948
   KEYWORD: 3D-structure    Alternative splicing    Angiogenesis    ATP-binding    Glycoprotein    Immunoglobulin domain    Kinase    Phosphorylation    Receptor    Repeat    Signal    Transferase    Transmembrane    Tyrosine-protein kinase   
EC: 2.7.1.112
SCOP: b.1.1.4 All beta proteins    Immunoglobulin-like beta-sandwich    Immunoglobulin    I set domains    Second domain of the Flt-1 receptor    Human (Homo sapiens)
GO:  membrane    ATP binding    protein kinase activity    protein-tyrosine kinase activity    transmembrane receptor protein tyrosine kinase activity    vascular endothelial growth factor receptor activity    protein amino acid phosphorylation    transmembrane receptor protein tyrosine kinase signaling pathway   
1flt Image
Image Source: PDB

Stored Loops of 1flt

Loops in ArchDB40 clusters

1flt_X_184 - HA => SUBCLASS : 3.2.1
1flt_X_168 - HA => SUBCLASS : 3.28.1
1flt_X_144 - AR => SUBCLASS : 3.3.2
1flt_X_144 - AR => SUBCLASS : 4.1.1
1flt_X_144 - AR => SUBCLASS : 4.1.2

Loops in ArchDB95 clusters

1flt_X_144 - AR => SUBCLASS : 2.3.1
1flt_X_144 - AR => SUBCLASS : 3.5.2
1flt_X_144 - AR => SUBCLASS : 3.6.1
1flt_X_191 - AR => SUBCLASS : 7.1.1
1flt_X_191 - AR => SUBCLASS : 7.1.2
1flt_X_184 - HA => SUBCLASS : 3.3.1
1flt_X_168 - HA => SUBCLASS : 3.25.1

Loops in ArchDB-EC clusters

1flt_X_168 - HA => SUBCLASS : 3.20.1

Loops not clustered in ArchDB

1flt_X_154 - AR
1flt_X_144 - AR
1flt_X_175 - AR
1flt_X_154 - AR
1flt_V_51 - AR
1flt_V_46 - AR
1flt_X_191 - AR
1flt_X_175 - AR
1flt_V_27 - EH
1flt_X_168 - HA
1flt_X_184 - HA
1flt_X_203 - HA
1flt_V_66 - HA
1flt_X_203 - HA
1flt_V_17 - HE
1flt_V_35 - HE

Homologous structures to 1flt classified in ArchDB

1flt X - percentage of sequence identity: 100
1flt Y - percentage of sequence identity: 100
1qsv A - percentage of sequence identity: 100
1qsz A - percentage of sequence identity: 100
1qty T - percentage of sequence identity: 100
1qty U - percentage of sequence identity: 100
1qty X - percentage of sequence identity: 100
1qty Y - percentage of sequence identity: 100
1rv6 X - percentage of sequence identity: 100
1rv6 Y - percentage of sequence identity: 100
null nu - percentage of sequence identity: 0