Logo
Information on 1fq9
PDB: 1fq9
Compound: fibroblast growth factor 2
Classification: GROWTH FACTOR/GROWTH FACTOR RECEPTOR
Entry date in PDB: 2000-09-27
Resolution [Å]: 3.00
R-Factor: 0.229


CHAIN: A
SWISS-PROT/TREMBL: P09038
   KEYWORD: 3D-structure    Angiogenesis    Growth factor    Heparin-binding    Mitogen   
SCOP: b.42.1.1 All beta proteins    beta-Trefoil    Cytokine    Fibroblast growth factors (FGF)    Basic FGF (FGF2)    Human (Homo sapiens)
GO:  growth factor activity   


CHAIN: B
SWISS-PROT/TREMBL: P09038
   KEYWORD: 3D-structure    Angiogenesis    Growth factor    Heparin-binding    Mitogen   
SCOP: b.42.1.1 All beta proteins    beta-Trefoil    Cytokine    Fibroblast growth factors (FGF)    Basic FGF (FGF2)    Human (Homo sapiens)
GO:  growth factor activity   


CHAIN: C
SWISS-PROT/TREMBL: P11362
   KEYWORD: 3D-structure    Alternative splicing    ATP-binding    Chromosomal translocation    Disease mutation    Glycoprotein    Immunoglobulin domain    Phosphorylation    Receptor    Repeat    Signal    Transferase    Transmembrane    Tyrosine-protein kinase   
EC: 2.7.1.112
SCOP: b.1.1.4 All beta proteins    Immunoglobulin-like beta-sandwich    Immunoglobulin    I set domains    Fibroblast growth factor receptor, FGFR    Human (Homo sapiens), FGFR1
SCOP: b.1.1.4 All beta proteins    Immunoglobulin-like beta-sandwich    Immunoglobulin    I set domains    Fibroblast growth factor receptor, FGFR    Human (Homo sapiens), FGFR1
GO:  ATP binding    protein kinase activity    protein-tyrosine kinase activity    protein amino acid phosphorylation   


CHAIN: D
SWISS-PROT/TREMBL: P11362
   KEYWORD: 3D-structure    Alternative splicing    ATP-binding    Chromosomal translocation    Disease mutation    Glycoprotein    Immunoglobulin domain    Phosphorylation    Receptor    Repeat    Signal    Transferase    Transmembrane    Tyrosine-protein kinase   
EC: 2.7.1.112
SCOP: b.1.1.4 All beta proteins    Immunoglobulin-like beta-sandwich    Immunoglobulin    I set domains    Fibroblast growth factor receptor, FGFR    Human (Homo sapiens), FGFR1
SCOP: b.1.1.4 All beta proteins    Immunoglobulin-like beta-sandwich    Immunoglobulin    I set domains    Fibroblast growth factor receptor, FGFR    Human (Homo sapiens), FGFR1
GO:  ATP binding    protein kinase activity    protein-tyrosine kinase activity    protein amino acid phosphorylation   
1fq9 Image
Image Source: PDB
Homologous structures to 1fq9 classified in ArchDB

1bfg - - percentage of sequence identity: 100
1cvs C - percentage of sequence identity: 100
1ev2 E - percentage of sequence identity: 79
1evt C - percentage of sequence identity: 99
1iil E - percentage of sequence identity: 78
1nun B - percentage of sequence identity: 71