PDB: 1fxy Compound: coagulation factor xa-trypsin chimera Classification: COMPLEX (PROTEASE/INHIBITOR) Entry date in PDB: 1998-06-17 Resolution [Å]: 2.15 R-Factor: 0.180

CHAIN: A SWISS-PROT/TREMBL: P00742    KEYWORD: 3D-structure    Blood coagulation    Calcium-binding    EGF-like domain    Gamma-carboxyglutamic acid    Glycoprotein    Hydrolase    Hydroxylation    Plasma    Polymorphism    Repeat    Serine protease    Signal    Vitamin K    Zymogen    3D-structure    Calcium-binding    Digestion    Disease mutation    Hydrolase    Multigene family    Pancreas    Phosphorylation    Serine protease    Signal    Zymogen    EC: 3.4.21.6 SCOP: b.47.1.2 All beta proteins    Trypsin-like serine proteases    Trypsin-like serine proteases    Eukaryotic proteases    Coagulation factor Xa-trypsin chimera    Synthetic, based on Homo sapiens sequence GO:  extracellular region    calcium ion binding    chymotrypsin activity    chymotrypsin activity    trypsin activity    trypsin activity    proteolysis and peptidolysis    proteolysis and peptidolysis

Image Source: PDB

Loops in ArchDB95 clusters

1fxy_A_226 - EH => SUBCLASS : 0.1.2
1fxy_A_156 - EH => SUBCLASS : 3.1.3
1fxy_A_20 - AR => SUBCLASS : 8.3.1
1fxy_A_104 - AR => SUBCLASS : 24.1.1
1fxy_A_30 - HA => SUBCLASS : 5.1.2
1fxy_A_204 - HA => SUBCLASS : 10.1.1
1fxy_A_135 - HA => SUBCLASS : 15.3.1

Loops in ArchDB-EC clusters

1fxy_A_165 - HE => SUBCLASS : 8.6.1

Loops not clustered in ArchDB

1fxy_A_51 - AR
1fxy_A_51 - AR
1fxy_A_180 - AR
1fxy_A_180 - AR
1fxy_A_104 - AR
1fxy_A_20 - AR
1fxy_A_80 - HA
1fxy_A_135 - HA
1fxy_A_198 - HA
1fxy_A_40 - HA
1fxy_A_65 - HA
1fxy_A_40 - HA
1fxy_A_30 - HA
1fxy_A_198 - HA
1fxy_A_80 - HA
1fxy_A_65 - HA
1fxy_A_204 - HA

1aks B - percentage of sequence identity: 79
1c5m D - percentage of sequence identity: 65
1ept C - percentage of sequence identity: 79
1ezq A - percentage of sequence identity: 65
1f0r A - percentage of sequence identity: 65
1f0s A - percentage of sequence identity: 65
1fax A - percentage of sequence identity: 64
1fjs A - percentage of sequence identity: 65
1g2l A - percentage of sequence identity: 65
1g2m A - percentage of sequence identity: 65
1hcg A - percentage of sequence identity: 65
1ioe A - percentage of sequence identity: 65
1iqe A - percentage of sequence identity: 65
1iqf A - percentage of sequence identity: 65
1iqg A - percentage of sequence identity: 65
1iqh A - percentage of sequence identity: 65
1iqi A - percentage of sequence identity: 65
1iqj A - percentage of sequence identity: 65
1iqk A - percentage of sequence identity: 65
1iql A - percentage of sequence identity: 65
1iqm A - percentage of sequence identity: 65
1iqn A - percentage of sequence identity: 65
1ksn A - percentage of sequence identity: 65
1kye A - percentage of sequence identity: 65
1lpg B - percentage of sequence identity: 65
1lpk B - percentage of sequence identity: 65
1lpz B - percentage of sequence identity: 65
1lqd B - percentage of sequence identity: 65
1mq5 A - percentage of sequence identity: 65
1mq6 A - percentage of sequence identity: 65
1nfu A - percentage of sequence identity: 65
1nfw A - percentage of sequence identity: 65
1nfx A - percentage of sequence identity: 65
1nfy A - percentage of sequence identity: 65
1p0s H - percentage of sequence identity: 65
1trn B - percentage of sequence identity: 69
1uhb B - percentage of sequence identity: 80
1v3x A - percentage of sequence identity: 65
1wu1 A - percentage of sequence identity: 65
1xka C - percentage of sequence identity: 65
1xkb C - percentage of sequence identity: 65
1xkb D - percentage of sequence identity: 65
2bok A - percentage of sequence identity: 65