PDB: 1ges Compound: Glutathione reductase nad mutant with ala 179 repl Classification: OXIDOREDUCTASE(FLAVOENZYME) Entry date in PDB: 1994-11-01 Resolution [Å]: 1.74 R-Factor: 0.168

CHAIN: A SWISS-PROT/TREMBL: P06715    KEYWORD: 3D-structure    Complete proteome    FAD    Flavoprotein    NADP    Oxidoreductase    Redox-active center    EC: 1.8.1.7 SCOP: c.3.1.5 Alpha and beta proteins (a/b)    FAD/NAD(P)-binding domain    FAD/NAD(P)-binding domain    FAD/NAD-linked reductases, N-terminal and central domains    Glutathione reductase    Escherichia coli SCOP: c.3.1.5 Alpha and beta proteins (a/b)    FAD/NAD(P)-binding domain    FAD/NAD(P)-binding domain    FAD/NAD-linked reductases, N-terminal and central domains    Glutathione reductase    Escherichia coli SCOP: c.3.1.5 Alpha and beta proteins (a/b)    FAD/NAD(P)-binding domain    FAD/NAD(P)-binding domain    FAD/NAD-linked reductases, N-terminal and central domains    Glutathione reductase    Escherichia coli SCOP: d.87.1.1 Alpha and beta proteins (a+b)    CO dehydrogenase flavoprotein C-domain-like    FAD/NAD-linked reductases, dimerisation (C-terminal) domain    FAD/NAD-linked reductases, dimerisation (C-terminal) domain    Glutathione reductase    Escherichia coli GO:  cytoplasm    disulfide oxidoreductase activity    FAD binding    glutathione-disulfide reductase activity    oxidoreductase activity    electron transport    glutathione metabolism    CHAIN: B SWISS-PROT/TREMBL: P06715    KEYWORD: 3D-structure    Complete proteome    FAD    Flavoprotein    NADP    Oxidoreductase    Redox-active center    EC: 1.8.1.7 SCOP: c.3.1.5 Alpha and beta proteins (a/b)    FAD/NAD(P)-binding domain    FAD/NAD(P)-binding domain    FAD/NAD-linked reductases, N-terminal and central domains    Glutathione reductase    Escherichia coli SCOP: c.3.1.5 Alpha and beta proteins (a/b)    FAD/NAD(P)-binding domain    FAD/NAD(P)-binding domain    FAD/NAD-linked reductases, N-terminal and central domains    Glutathione reductase    Escherichia coli SCOP: c.3.1.5 Alpha and beta proteins (a/b)    FAD/NAD(P)-binding domain    FAD/NAD(P)-binding domain    FAD/NAD-linked reductases, N-terminal and central domains    Glutathione reductase    Escherichia coli SCOP: d.87.1.1 Alpha and beta proteins (a+b)    CO dehydrogenase flavoprotein C-domain-like    FAD/NAD-linked reductases, dimerisation (C-terminal) domain    FAD/NAD-linked reductases, dimerisation (C-terminal) domain    Glutathione reductase    Escherichia coli GO:  cytoplasm    disulfide oxidoreductase activity    FAD binding    glutathione-disulfide reductase activity    oxidoreductase activity    electron transport    glutathione metabolism

Image Source: PDB

Loops in ArchDB95 clusters

1ges_A_368 - EH => SUBCLASS : 1.1.13
1ges_A_368 - EH => SUBCLASS : 1.1.14
1ges_A_401 - EH => SUBCLASS : 3.11.1
1ges_A_30 - EH => SUBCLASS : 5.67.1
1ges_A_192 - EH => SUBCLASS : 10.2.1
1ges_A_224 - AR => SUBCLASS : 2.6.1
1ges_A_81 - HE => SUBCLASS : 1.1.1
1ges_A_177 - HE => SUBCLASS : 1.1.1
1ges_A_14 - HE => SUBCLASS : 2.1.1
1ges_A_378 - HE => SUBCLASS : 4.1.9
1ges_A_356 - HE => SUBCLASS : 4.10.2
1ges_A_157 - HE => SUBCLASS : 6.16.2
1ges_A_272 - HE => SUBCLASS : 22.1.1
1ges_A_116 - HA => SUBCLASS : 2.2.1
1ges_A_231 - HA => SUBCLASS : 3.1.1
1ges_A_242 - HA => SUBCLASS : 3.1.2
1ges_A_388 - HA => SUBCLASS : 4.7.3

Loops in ArchDB-EC clusters

1ges_A_356 - HE => SUBCLASS : 4.58.1

Loops not clustered in ArchDB

1ges_A_251 - AR
1ges_A_128 - AR
1ges_A_256 - AR
1ges_A_109 - AR
1ges_A_128 - AR
1ges_A_224 - AR
1ges_A_251 - AR
1ges_A_256 - AR
1ges_A_109 - AR
1ges_A_4 - EH
1ges_A_141 - EH
1ges_A_169 - EH
1ges_A_263 - EH
1ges_A_349 - EH
1ges_A_298 - EH
1ges_A_388 - HA
1ges_A_341 - HA
1ges_A_242 - HA
1ges_A_231 - HA
1ges_A_122 - HA
1ges_A_116 - HA
1ges_A_341 - HA
1ges_A_122 - HA
1ges_A_208 - HE
1ges_A_311 - HE
1ges_A_40 - HH
1ges_A_47 - HH
1ges_A_412 - HH

1ger A - percentage of sequence identity: 98
1ger B - percentage of sequence identity: 98
1ges A - percentage of sequence identity: 100
1ges B - percentage of sequence identity: 100
1get A - percentage of sequence identity: 98
1get B - percentage of sequence identity: 98
1geu A - percentage of sequence identity: 100
1geu B - percentage of sequence identity: 100