PDB: 1gpm Compound: gmp synthetase Classification: TRANSFERASE (GLUTAMINE AMIDOTRANSFERASE) Entry date in PDB: 1996-01-29 Resolution [Å]: 2.20 R-Factor: 0.174

CHAIN: A SWISS-PROT/TREMBL: P04079    KEYWORD: 3D-structure    ATP-binding    Complete proteome    Glutamine amidotransferase    GMP biosynthesis    Ligase    Purine biosynthesis    EC: 6.3.5.2 SCOP: c.23.16.1 Alpha and beta proteins (a/b)    Flavodoxin-like    Class I glutamine amidotransferase-like    Class I glutamine amidotransferases (GAT)    GMP synthetase    Escherichia coli SCOP: c.26.2.1 Alpha and beta proteins (a/b)    Adenine nucleotide alpha hydrolase-like    Adenine nucleotide alpha hydrolases-like    N-type ATP pyrophosphatases    GMP synthetase, central domain    Escherichia coli SCOP: d.52.2.1 Alpha and beta proteins (a+b)    Alpha-lytic protease prodomain-like    GMP synthetase C-terminal dimerisation domain    GMP synthetase C-terminal dimerisation domain    GMP synthetase C-terminal dimerisation domain    Escherichia coli GO:  cytoplasm    ATP binding    catalytic activity    GMP synthase (glutamine-hydrolyzing) activity    tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity    biosynthesis    glutamine metabolism    GMP biosynthesis    purine nucleotide biosynthesis    tRNA processing    CHAIN: B SWISS-PROT/TREMBL: P04079    KEYWORD: 3D-structure    ATP-binding    Complete proteome    Glutamine amidotransferase    GMP biosynthesis    Ligase    Purine biosynthesis    EC: 6.3.5.2 SCOP: c.23.16.1 Alpha and beta proteins (a/b)    Flavodoxin-like    Class I glutamine amidotransferase-like    Class I glutamine amidotransferases (GAT)    GMP synthetase    Escherichia coli SCOP: c.26.2.1 Alpha and beta proteins (a/b)    Adenine nucleotide alpha hydrolase-like    Adenine nucleotide alpha hydrolases-like    N-type ATP pyrophosphatases    GMP synthetase, central domain    Escherichia coli SCOP: d.52.2.1 Alpha and beta proteins (a+b)    Alpha-lytic protease prodomain-like    GMP synthetase C-terminal dimerisation domain    GMP synthetase C-terminal dimerisation domain    GMP synthetase C-terminal dimerisation domain    Escherichia coli GO:  cytoplasm    ATP binding    catalytic activity    GMP synthase (glutamine-hydrolyzing) activity    tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity    biosynthesis    glutamine metabolism    GMP biosynthesis    purine nucleotide biosynthesis    tRNA processing    CHAIN: C SWISS-PROT/TREMBL: P04079    KEYWORD: 3D-structure    ATP-binding    Complete proteome    Glutamine amidotransferase    GMP biosynthesis    Ligase    Purine biosynthesis    EC: 6.3.5.2 SCOP: c.23.16.1 Alpha and beta proteins (a/b)    Flavodoxin-like    Class I glutamine amidotransferase-like    Class I glutamine amidotransferases (GAT)    GMP synthetase    Escherichia coli SCOP: c.26.2.1 Alpha and beta proteins (a/b)    Adenine nucleotide alpha hydrolase-like    Adenine nucleotide alpha hydrolases-like    N-type ATP pyrophosphatases    GMP synthetase, central domain    Escherichia coli SCOP: d.52.2.1 Alpha and beta proteins (a+b)    Alpha-lytic protease prodomain-like    GMP synthetase C-terminal dimerisation domain    GMP synthetase C-terminal dimerisation domain    GMP synthetase C-terminal dimerisation domain    Escherichia coli GO:  cytoplasm    ATP binding    catalytic activity    GMP synthase (glutamine-hydrolyzing) activity    tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity    biosynthesis    glutamine metabolism    GMP biosynthesis    purine nucleotide biosynthesis    tRNA processing    CHAIN: D SWISS-PROT/TREMBL: P04079    KEYWORD: 3D-structure    ATP-binding    Complete proteome    Glutamine amidotransferase    GMP biosynthesis    Ligase    Purine biosynthesis    EC: 6.3.5.2 SCOP: c.23.16.1 Alpha and beta proteins (a/b)    Flavodoxin-like    Class I glutamine amidotransferase-like    Class I glutamine amidotransferases (GAT)    GMP synthetase    Escherichia coli SCOP: c.26.2.1 Alpha and beta proteins (a/b)    Adenine nucleotide alpha hydrolase-like    Adenine nucleotide alpha hydrolases-like    N-type ATP pyrophosphatases    GMP synthetase, central domain    Escherichia coli SCOP: d.52.2.1 Alpha and beta proteins (a+b)    Alpha-lytic protease prodomain-like    GMP synthetase C-terminal dimerisation domain    GMP synthetase C-terminal dimerisation domain    GMP synthetase C-terminal dimerisation domain    Escherichia coli GO:  cytoplasm    ATP binding    catalytic activity    GMP synthase (glutamine-hydrolyzing) activity    tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity    biosynthesis    glutamine metabolism    GMP biosynthesis    purine nucleotide biosynthesis    tRNA processing

Image Source: PDB

Loops in ArchDB40 clusters

1gpm_A_167 - HA => SUBCLASS : 4.1.1
1gpm_A_128 - HA => SUBCLASS : 5.3.2
1gpm_A_285 - EH => SUBCLASS : 0.1.10
1gpm_A_82 - EH => SUBCLASS : 1.2.2
1gpm_A_229 - EH => SUBCLASS : 3.21.1
1gpm_A_329 - EH => SUBCLASS : 3.28.1
1gpm_A_9 - EH => SUBCLASS : 3.35.1
1gpm_A_482 - EH => SUBCLASS : 4.13.1
1gpm_A_482 - EH => SUBCLASS : 4.13.3
1gpm_A_371 - EH => SUBCLASS : 6.33.1
1gpm_A_175 - EH => SUBCLASS : 9.9.1
1gpm_A_135 - AR => SUBCLASS : 1.1.7
1gpm_A_99 - AR => SUBCLASS : 4.38.1
1gpm_A_381 - HH => SUBCLASS : 3.3.1

Loops in ArchDB95 clusters

1gpm_A_285 - EH => SUBCLASS : 0.1.27
1gpm_A_82 - EH => SUBCLASS : 1.3.2
1gpm_A_482 - EH => SUBCLASS : 3.1.6
1gpm_A_329 - EH => SUBCLASS : 3.21.1
1gpm_A_229 - EH => SUBCLASS : 3.23.1
1gpm_A_9 - EH => SUBCLASS : 3.43.1
1gpm_A_33 - EH => SUBCLASS : 4.4.8
1gpm_A_482 - EH => SUBCLASS : 4.10.2
1gpm_A_371 - EH => SUBCLASS : 6.59.1
1gpm_A_135 - AR => SUBCLASS : 1.2.19
1gpm_A_146 - AR => SUBCLASS : 5.80.1
1gpm_A_381 - HH => SUBCLASS : 3.2.1
1gpm_A_20 - HE => SUBCLASS : 1.1.1
1gpm_A_87 - HE => SUBCLASS : 1.1.1
1gpm_A_87 - HE => SUBCLASS : 2.1.1
1gpm_A_43 - HE => SUBCLASS : 3.3.2
1gpm_A_490 - HE => SUBCLASS : 3.7.1
1gpm_A_490 - HE => SUBCLASS : 3.10.3
1gpm_A_304 - HE => SUBCLASS : 3.10.5
1gpm_A_238 - HE => SUBCLASS : 3.11.1
1gpm_A_304 - HE => SUBCLASS : 3.22.2
1gpm_A_210 - HE => SUBCLASS : 4.26.1
1gpm_A_418 - HE => SUBCLASS : 7.6.1
1gpm_A_167 - HA => SUBCLASS : 4.1.1
1gpm_A_128 - HA => SUBCLASS : 5.4.4

Loops in ArchDB-EC clusters

1gpm_A_381 - HH => SUBCLASS : 3.2.1

Loops not clustered in ArchDB

1gpm_A_135 - AR
1gpm_A_99 - AR
1gpm_A_107 - AR
1gpm_A_107 - AR
1gpm_A_146 - AR
1gpm_A_255 - EH
1gpm_A_128 - HA
1gpm_A_155 - HA
1gpm_A_167 - HA
1gpm_A_446 - HA
1gpm_A_53 - HA
1gpm_A_466 - HA
1gpm_A_466 - HA
1gpm_A_53 - HA
1gpm_A_155 - HA
1gpm_A_446 - HA
1gpm_A_338 - HE
1gpm_A_269 - HE
1gpm_A_395 - HH
1gpm_A_190 - HH
1gpm_A_291 - HH

1gpm A - percentage of sequence identity: 100
1gpm B - percentage of sequence identity: 100
1gpm C - percentage of sequence identity: 100
1gpm D - percentage of sequence identity: 100