PDB: 1gth Compound: dihydropyrimidine dehydrogenase Classification: OXIDOREDUCTASE Entry date in PDB: 2002-04-11 Resolution [Å]: 2.25 R-Factor: 0.177

CHAIN: A SWISS-PROT/TREMBL: Q28943    KEYWORD: 3D-structure    4Fe-4S    FAD    Flavoprotein    FMN    Iron-sulfur    NADP    Oxidoreductase    EC: 1.3.1.2 SCOP: a.1.2.2 All alpha proteins    Globin-like    alpha-helical ferredoxin    Dihydropyrimidine dehydrogenase, N-terminal domain    Dihydropyrimidine dehydrogenase, N-terminal domain    Pig (Sus scrofa) SCOP: c.1.4.1 Alpha and beta proteins (a/b)    TIM beta/alpha-barrel    FMN-linked oxidoreductases    FMN-linked oxidoreductases    Dihydropyrimidine dehydrogenase, domain 4    Pig (Sus scrofa) SCOP: c.3.1.1 Alpha and beta proteins (a/b)    FAD/NAD(P)-binding domain    FAD/NAD(P)-binding domain    C-terminal domain of adrenodoxin reductase-like    Dihydropyrimidine dehydrogenase, domain 3    Pig (Sus scrofa) SCOP: c.4.1.1 Alpha and beta proteins (a/b)    Nucleotide-binding domain    Nucleotide-binding domain    N-terminal domain of adrenodoxin reductase-like    Dihydropyrimidine dehydrogenase, domain 2    Pig (Sus scrofa) SCOP: c.4.1.1 Alpha and beta proteins (a/b)    Nucleotide-binding domain    Nucleotide-binding domain    N-terminal domain of adrenodoxin reductase-like    Dihydropyrimidine dehydrogenase, domain 2    Pig (Sus scrofa) SCOP: d.58.1.5 Alpha and beta proteins (a+b)    Ferredoxin-like    4Fe-4S ferredoxins    Ferredoxin domains from multidomain proteins    Dihydropyrimidine dehydrogenase, C-terminal domain    Pig (Sus scrofa) GO:  cytoplasm    membrane    dihydroorotate dehydrogenase activity    dihydroorotate oxidase activity    disulfide oxidoreductase activity    electron transporter activity    iron ion binding    oxidoreductase activity    'de novo' pyrimidine base biosynthesis    electron transport    CHAIN: B SWISS-PROT/TREMBL: Q28943    KEYWORD: 3D-structure    4Fe-4S    FAD    Flavoprotein    FMN    Iron-sulfur    NADP    Oxidoreductase    EC: 1.3.1.2 SCOP: a.1.2.2 All alpha proteins    Globin-like    alpha-helical ferredoxin    Dihydropyrimidine dehydrogenase, N-terminal domain    Dihydropyrimidine dehydrogenase, N-terminal domain    Pig (Sus scrofa) SCOP: c.1.4.1 Alpha and beta proteins (a/b)    TIM beta/alpha-barrel    FMN-linked oxidoreductases    FMN-linked oxidoreductases    Dihydropyrimidine dehydrogenase, domain 4    Pig (Sus scrofa) SCOP: c.3.1.1 Alpha and beta proteins (a/b)    FAD/NAD(P)-binding domain    FAD/NAD(P)-binding domain    C-terminal domain of adrenodoxin reductase-like    Dihydropyrimidine dehydrogenase, domain 3    Pig (Sus scrofa) SCOP: c.4.1.1 Alpha and beta proteins (a/b)    Nucleotide-binding domain    Nucleotide-binding domain    N-terminal domain of adrenodoxin reductase-like    Dihydropyrimidine dehydrogenase, domain 2    Pig (Sus scrofa) SCOP: c.4.1.1 Alpha and beta proteins (a/b)    Nucleotide-binding domain    Nucleotide-binding domain    N-terminal domain of adrenodoxin reductase-like    Dihydropyrimidine dehydrogenase, domain 2    Pig (Sus scrofa) SCOP: d.58.1.5 Alpha and beta proteins (a+b)    Ferredoxin-like    4Fe-4S ferredoxins    Ferredoxin domains from multidomain proteins    Dihydropyrimidine dehydrogenase, C-terminal domain    Pig (Sus scrofa) GO:  cytoplasm    membrane    dihydroorotate dehydrogenase activity    dihydroorotate oxidase activity    disulfide oxidoreductase activity    electron transporter activity    iron ion binding    oxidoreductase activity    'de novo' pyrimidine base biosynthesis    electron transport    CHAIN: C SWISS-PROT/TREMBL: Q28943    KEYWORD: 3D-structure    4Fe-4S    FAD    Flavoprotein    FMN    Iron-sulfur    NADP    Oxidoreductase    EC: 1.3.1.2 SCOP: a.1.2.2 All alpha proteins    Globin-like    alpha-helical ferredoxin    Dihydropyrimidine dehydrogenase, N-terminal domain    Dihydropyrimidine dehydrogenase, N-terminal domain    Pig (Sus scrofa) SCOP: c.1.4.1 Alpha and beta proteins (a/b)    TIM beta/alpha-barrel    FMN-linked oxidoreductases    FMN-linked oxidoreductases    Dihydropyrimidine dehydrogenase, domain 4    Pig (Sus scrofa) SCOP: c.3.1.1 Alpha and beta proteins (a/b)    FAD/NAD(P)-binding domain    FAD/NAD(P)-binding domain    C-terminal domain of adrenodoxin reductase-like    Dihydropyrimidine dehydrogenase, domain 3    Pig (Sus scrofa) SCOP: c.4.1.1 Alpha and beta proteins (a/b)    Nucleotide-binding domain    Nucleotide-binding domain    N-terminal domain of adrenodoxin reductase-like    Dihydropyrimidine dehydrogenase, domain 2    Pig (Sus scrofa) SCOP: c.4.1.1 Alpha and beta proteins (a/b)    Nucleotide-binding domain    Nucleotide-binding domain    N-terminal domain of adrenodoxin reductase-like    Dihydropyrimidine dehydrogenase, domain 2    Pig (Sus scrofa) SCOP: d.58.1.5 Alpha and beta proteins (a+b)    Ferredoxin-like    4Fe-4S ferredoxins    Ferredoxin domains from multidomain proteins    Dihydropyrimidine dehydrogenase, C-terminal domain    Pig (Sus scrofa) GO:  cytoplasm    membrane    dihydroorotate dehydrogenase activity    dihydroorotate oxidase activity    disulfide oxidoreductase activity    electron transporter activity    iron ion binding    oxidoreductase activity    'de novo' pyrimidine base biosynthesis    electron transport    CHAIN: D SWISS-PROT/TREMBL: Q28943    KEYWORD: 3D-structure    4Fe-4S    FAD    Flavoprotein    FMN    Iron-sulfur    NADP    Oxidoreductase    EC: 1.3.1.2 SCOP: a.1.2.2 All alpha proteins    Globin-like    alpha-helical ferredoxin    Dihydropyrimidine dehydrogenase, N-terminal domain    Dihydropyrimidine dehydrogenase, N-terminal domain    Pig (Sus scrofa) SCOP: c.1.4.1 Alpha and beta proteins (a/b)    TIM beta/alpha-barrel    FMN-linked oxidoreductases    FMN-linked oxidoreductases    Dihydropyrimidine dehydrogenase, domain 4    Pig (Sus scrofa) SCOP: c.3.1.1 Alpha and beta proteins (a/b)    FAD/NAD(P)-binding domain    FAD/NAD(P)-binding domain    C-terminal domain of adrenodoxin reductase-like    Dihydropyrimidine dehydrogenase, domain 3    Pig (Sus scrofa) SCOP: c.4.1.1 Alpha and beta proteins (a/b)    Nucleotide-binding domain    Nucleotide-binding domain    N-terminal domain of adrenodoxin reductase-like    Dihydropyrimidine dehydrogenase, domain 2    Pig (Sus scrofa) SCOP: c.4.1.1 Alpha and beta proteins (a/b)    Nucleotide-binding domain    Nucleotide-binding domain    N-terminal domain of adrenodoxin reductase-like    Dihydropyrimidine dehydrogenase, domain 2    Pig (Sus scrofa) SCOP: d.58.1.5 Alpha and beta proteins (a+b)    Ferredoxin-like    4Fe-4S ferredoxins    Ferredoxin domains from multidomain proteins    Dihydropyrimidine dehydrogenase, C-terminal domain    Pig (Sus scrofa) GO:  cytoplasm    membrane    dihydroorotate dehydrogenase activity    dihydroorotate oxidase activity    disulfide oxidoreductase activity    electron transporter activity    iron ion binding    oxidoreductase activity    'de novo' pyrimidine base biosynthesis    electron transport

Image Source: PDB

1gte A - percentage of sequence identity: 100
1h7w A - percentage of sequence identity: 100