PDB: 1gyt Compound: cytosol aminopeptidase Classification: HYDROLASE Entry date in PDB: 2002-06-06 Resolution [Å]: 2.50 R-Factor: 0.165

CHAIN: A SWISS-PROT/TREMBL: P11648    KEYWORD: 3D-structure    Aminopeptidase    Complete proteome    Hydrolase    Manganese    EC: 3.4.11.1 SCOP: c.56.5.3 Alpha and beta proteins (a/b)    Phosphorylase/hydrolase-like    Zn-dependent exopeptidases    Leucine aminopeptidase, C-terminal domain    Leucine aminopeptidase, C-terminal domain    Escherichia coli, PepA SCOP: c.50.1.1 Alpha and beta proteins (a/b)    Macro domain-like    Macro domain-like    Leucine aminopeptidase (Aminopeptidase A), N-terminal domain    Leucine aminopeptidase (Aminopeptidase A), N-terminal domain    Escherichia coli, PepA GO:  cytoplasm    intracellular    aminopeptidase activity    leucyl aminopeptidase activity    manganese ion binding    protein metabolism    proteolysis and peptidolysis    CHAIN: B SWISS-PROT/TREMBL: P11648    KEYWORD: 3D-structure    Aminopeptidase    Complete proteome    Hydrolase    Manganese    EC: 3.4.11.1 SCOP: c.56.5.3 Alpha and beta proteins (a/b)    Phosphorylase/hydrolase-like    Zn-dependent exopeptidases    Leucine aminopeptidase, C-terminal domain    Leucine aminopeptidase, C-terminal domain    Escherichia coli, PepA SCOP: c.50.1.1 Alpha and beta proteins (a/b)    Macro domain-like    Macro domain-like    Leucine aminopeptidase (Aminopeptidase A), N-terminal domain    Leucine aminopeptidase (Aminopeptidase A), N-terminal domain    Escherichia coli, PepA GO:  cytoplasm    intracellular    aminopeptidase activity    leucyl aminopeptidase activity    manganese ion binding    protein metabolism    proteolysis and peptidolysis    CHAIN: C SWISS-PROT/TREMBL: P11648    KEYWORD: 3D-structure    Aminopeptidase    Complete proteome    Hydrolase    Manganese    EC: 3.4.11.1 SCOP: c.56.5.3 Alpha and beta proteins (a/b)    Phosphorylase/hydrolase-like    Zn-dependent exopeptidases    Leucine aminopeptidase, C-terminal domain    Leucine aminopeptidase, C-terminal domain    Escherichia coli, PepA SCOP: c.50.1.1 Alpha and beta proteins (a/b)    Macro domain-like    Macro domain-like    Leucine aminopeptidase (Aminopeptidase A), N-terminal domain    Leucine aminopeptidase (Aminopeptidase A), N-terminal domain    Escherichia coli, PepA GO:  cytoplasm    intracellular    aminopeptidase activity    leucyl aminopeptidase activity    manganese ion binding    protein metabolism    proteolysis and peptidolysis    CHAIN: D SWISS-PROT/TREMBL: P11648    KEYWORD: 3D-structure    Aminopeptidase    Complete proteome    Hydrolase    Manganese    EC: 3.4.11.1 SCOP: c.56.5.3 Alpha and beta proteins (a/b)    Phosphorylase/hydrolase-like    Zn-dependent exopeptidases    Leucine aminopeptidase, C-terminal domain    Leucine aminopeptidase, C-terminal domain    Escherichia coli, PepA SCOP: c.50.1.1 Alpha and beta proteins (a/b)    Macro domain-like    Macro domain-like    Leucine aminopeptidase (Aminopeptidase A), N-terminal domain    Leucine aminopeptidase (Aminopeptidase A), N-terminal domain    Escherichia coli, PepA GO:  cytoplasm    intracellular    aminopeptidase activity    leucyl aminopeptidase activity    manganese ion binding    protein metabolism    proteolysis and peptidolysis    CHAIN: E SWISS-PROT/TREMBL: P11648    KEYWORD: 3D-structure    Aminopeptidase    Complete proteome    Hydrolase    Manganese    EC: 3.4.11.1 SCOP: c.56.5.3 Alpha and beta proteins (a/b)    Phosphorylase/hydrolase-like    Zn-dependent exopeptidases    Leucine aminopeptidase, C-terminal domain    Leucine aminopeptidase, C-terminal domain    Escherichia coli, PepA SCOP: c.50.1.1 Alpha and beta proteins (a/b)    Macro domain-like    Macro domain-like    Leucine aminopeptidase (Aminopeptidase A), N-terminal domain    Leucine aminopeptidase (Aminopeptidase A), N-terminal domain    Escherichia coli, PepA GO:  cytoplasm    intracellular    aminopeptidase activity    leucyl aminopeptidase activity    manganese ion binding    protein metabolism    proteolysis and peptidolysis    CHAIN: F SWISS-PROT/TREMBL: P11648    KEYWORD: 3D-structure    Aminopeptidase    Complete proteome    Hydrolase    Manganese    EC: 3.4.11.1 SCOP: c.56.5.3 Alpha and beta proteins (a/b)    Phosphorylase/hydrolase-like    Zn-dependent exopeptidases    Leucine aminopeptidase, C-terminal domain    Leucine aminopeptidase, C-terminal domain    Escherichia coli, PepA SCOP: c.50.1.1 Alpha and beta proteins (a/b)    Macro domain-like    Macro domain-like    Leucine aminopeptidase (Aminopeptidase A), N-terminal domain    Leucine aminopeptidase (Aminopeptidase A), N-terminal domain    Escherichia coli, PepA GO:  cytoplasm    intracellular    aminopeptidase activity    leucyl aminopeptidase activity    manganese ion binding    protein metabolism    proteolysis and peptidolysis    CHAIN: G SWISS-PROT/TREMBL: P11648    KEYWORD: 3D-structure    Aminopeptidase    Complete proteome    Hydrolase    Manganese    EC: 3.4.11.1 SCOP: c.56.5.3 Alpha and beta proteins (a/b)    Phosphorylase/hydrolase-like    Zn-dependent exopeptidases    Leucine aminopeptidase, C-terminal domain    Leucine aminopeptidase, C-terminal domain    Escherichia coli, PepA SCOP: c.50.1.1 Alpha and beta proteins (a/b)    Macro domain-like    Macro domain-like    Leucine aminopeptidase (Aminopeptidase A), N-terminal domain    Leucine aminopeptidase (Aminopeptidase A), N-terminal domain    Escherichia coli, PepA GO:  cytoplasm    intracellular    aminopeptidase activity    leucyl aminopeptidase activity    manganese ion binding    protein metabolism    proteolysis and peptidolysis    CHAIN: H SWISS-PROT/TREMBL: P11648    KEYWORD: 3D-structure    Aminopeptidase    Complete proteome    Hydrolase    Manganese    EC: 3.4.11.1 SCOP: c.56.5.3 Alpha and beta proteins (a/b)    Phosphorylase/hydrolase-like    Zn-dependent exopeptidases    Leucine aminopeptidase, C-terminal domain    Leucine aminopeptidase, C-terminal domain    Escherichia coli, PepA SCOP: c.50.1.1 Alpha and beta proteins (a/b)    Macro domain-like    Macro domain-like    Leucine aminopeptidase (Aminopeptidase A), N-terminal domain    Leucine aminopeptidase (Aminopeptidase A), N-terminal domain    Escherichia coli, PepA GO:  cytoplasm    intracellular    aminopeptidase activity    leucyl aminopeptidase activity    manganese ion binding    protein metabolism    proteolysis and peptidolysis    CHAIN: I SWISS-PROT/TREMBL: P11648    KEYWORD: 3D-structure    Aminopeptidase    Complete proteome    Hydrolase    Manganese    EC: 3.4.11.1 SCOP: c.56.5.3 Alpha and beta proteins (a/b)    Phosphorylase/hydrolase-like    Zn-dependent exopeptidases    Leucine aminopeptidase, C-terminal domain    Leucine aminopeptidase, C-terminal domain    Escherichia coli, PepA SCOP: c.50.1.1 Alpha and beta proteins (a/b)    Macro domain-like    Macro domain-like    Leucine aminopeptidase (Aminopeptidase A), N-terminal domain    Leucine aminopeptidase (Aminopeptidase A), N-terminal domain    Escherichia coli, PepA GO:  cytoplasm    intracellular    aminopeptidase activity    leucyl aminopeptidase activity    manganese ion binding    protein metabolism    proteolysis and peptidolysis    CHAIN: J SWISS-PROT/TREMBL: P11648    KEYWORD: 3D-structure    Aminopeptidase    Complete proteome    Hydrolase    Manganese    EC: 3.4.11.1 SCOP: c.56.5.3 Alpha and beta proteins (a/b)    Phosphorylase/hydrolase-like    Zn-dependent exopeptidases    Leucine aminopeptidase, C-terminal domain    Leucine aminopeptidase, C-terminal domain    Escherichia coli, PepA SCOP: c.50.1.1 Alpha and beta proteins (a/b)    Macro domain-like    Macro domain-like    Leucine aminopeptidase (Aminopeptidase A), N-terminal domain    Leucine aminopeptidase (Aminopeptidase A), N-terminal domain    Escherichia coli, PepA GO:  cytoplasm    intracellular    aminopeptidase activity    leucyl aminopeptidase activity    manganese ion binding    protein metabolism    proteolysis and peptidolysis    CHAIN: K SWISS-PROT/TREMBL: P11648    KEYWORD: 3D-structure    Aminopeptidase    Complete proteome    Hydrolase    Manganese    EC: 3.4.11.1 SCOP: c.56.5.3 Alpha and beta proteins (a/b)    Phosphorylase/hydrolase-like    Zn-dependent exopeptidases    Leucine aminopeptidase, C-terminal domain    Leucine aminopeptidase, C-terminal domain    Escherichia coli, PepA SCOP: c.50.1.1 Alpha and beta proteins (a/b)    Macro domain-like    Macro domain-like    Leucine aminopeptidase (Aminopeptidase A), N-terminal domain    Leucine aminopeptidase (Aminopeptidase A), N-terminal domain    Escherichia coli, PepA GO:  cytoplasm    intracellular    aminopeptidase activity    leucyl aminopeptidase activity    manganese ion binding    protein metabolism    proteolysis and peptidolysis    CHAIN: L SWISS-PROT/TREMBL: P11648    KEYWORD: 3D-structure    Aminopeptidase    Complete proteome    Hydrolase    Manganese    EC: 3.4.11.1 SCOP: c.56.5.3 Alpha and beta proteins (a/b)    Phosphorylase/hydrolase-like    Zn-dependent exopeptidases    Leucine aminopeptidase, C-terminal domain    Leucine aminopeptidase, C-terminal domain    Escherichia coli, PepA SCOP: c.50.1.1 Alpha and beta proteins (a/b)    Macro domain-like    Macro domain-like    Leucine aminopeptidase (Aminopeptidase A), N-terminal domain    Leucine aminopeptidase (Aminopeptidase A), N-terminal domain    Escherichia coli, PepA GO:  cytoplasm    intracellular    aminopeptidase activity    leucyl aminopeptidase activity    manganese ion binding    protein metabolism    proteolysis and peptidolysis

Image Source: PDB

Loops in ArchDB40 clusters

1gyt_A_200 - HE => SUBCLASS : 0.1.50
1gyt_A_400 - HE => SUBCLASS : 2.1.1
1gyt_A_382 - HE => SUBCLASS : 3.11.3
1gyt_A_295 - HE => SUBCLASS : 4.15.1
1gyt_A_337 - HA => SUBCLASS : 3.1.1
1gyt_A_218 - EH => SUBCLASS : 1.1.3
1gyt_A_393 - EH => SUBCLASS : 2.1.1
1gyt_A_156 - EH => SUBCLASS : 2.1.2
1gyt_A_156 - EH => SUBCLASS : 2.1.8
1gyt_A_225 - HH => SUBCLASS : 2.2.5

Loops in ArchDB95 clusters

1gyt_A_218 - EH => SUBCLASS : 1.1.4
1gyt_A_393 - EH => SUBCLASS : 2.1.1
1gyt_A_156 - EH => SUBCLASS : 2.1.5
1gyt_A_156 - EH => SUBCLASS : 2.1.11
1gyt_A_225 - HH => SUBCLASS : 2.2.3
1gyt_A_225 - HH => SUBCLASS : 2.2.7
1gyt_A_200 - HE => SUBCLASS : 0.1.21
1gyt_A_400 - HE => SUBCLASS : 2.1.1
1gyt_A_295 - HE => SUBCLASS : 3.1.3
1gyt_A_382 - HE => SUBCLASS : 3.11.3
1gyt_A_337 - HA => SUBCLASS : 3.1.1

Loops in ArchDB-EC clusters

1gyt_A_30 - HH => SUBCLASS : 2.9.1

Loops not clustered in ArchDB

1gyt_A_248 - AR
1gyt_A_315 - AR
1gyt_A_463 - AR
1gyt_A_2 - AR
1gyt_A_2 - AR
1gyt_A_248 - AR
1gyt_A_315 - AR
1gyt_A_463 - AR
1gyt_A_27 - EH
1gyt_A_480 - EH
1gyt_A_72 - EH
1gyt_A_107 - EH
1gyt_A_265 - EH
1gyt_A_345 - EH
1gyt_A_373 - EH
1gyt_A_417 - EH
1gyt_A_437 - EH
1gyt_A_18 - HA
1gyt_A_59 - HA
1gyt_A_473 - HA
1gyt_A_337 - HA
1gyt_A_59 - HA
1gyt_A_18 - HA
1gyt_A_473 - HA
1gyt_A_42 - HE
1gyt_A_86 - HE
1gyt_A_122 - HE
1gyt_A_234 - HE
1gyt_A_355 - HE
1gyt_A_424 - HE
1gyt_A_446 - HE
1gyt_A_167 - HH

1gyt A - percentage of sequence identity: 100
1gyt B - percentage of sequence identity: 100
1gyt C - percentage of sequence identity: 100
1gyt D - percentage of sequence identity: 100
1gyt E - percentage of sequence identity: 100
1gyt F - percentage of sequence identity: 100
1gyt G - percentage of sequence identity: 100
1gyt H - percentage of sequence identity: 100
1gyt I - percentage of sequence identity: 100
1gyt J - percentage of sequence identity: 100
1gyt K - percentage of sequence identity: 100
1gyt L - percentage of sequence identity: 100