PDB: 1h5q Compound: nadp-dependent mannitol dehydrogenase Classification: OXIDOREDUCTASE Entry date in PDB: 2001-06-21 Resolution [Å]: 1.50 R-Factor: 0.193

CHAIN: A SWISS-PROT/TREMBL: O93868    KEYWORD: 3D-structure    NADP    Oxidoreductase    EC: 1.1.1.138 SCOP: c.2.1.2 Alpha and beta proteins (a/b)    NAD(P)-binding Rossmann-fold domains    NAD(P)-binding Rossmann-fold domains    Tyrosine-dependent oxidoreductases    Mannitol dehydrogenase    Mushroom (Agaricus bisporus) GO:  oxidoreductase activity    metabolism    CHAIN: B SWISS-PROT/TREMBL: O93868    KEYWORD: 3D-structure    NADP    Oxidoreductase    EC: 1.1.1.138 SCOP: c.2.1.2 Alpha and beta proteins (a/b)    NAD(P)-binding Rossmann-fold domains    NAD(P)-binding Rossmann-fold domains    Tyrosine-dependent oxidoreductases    Mannitol dehydrogenase    Mushroom (Agaricus bisporus) GO:  oxidoreductase activity    metabolism    CHAIN: C SWISS-PROT/TREMBL: O93868    KEYWORD: 3D-structure    NADP    Oxidoreductase    EC: 1.1.1.138 SCOP: c.2.1.2 Alpha and beta proteins (a/b)    NAD(P)-binding Rossmann-fold domains    NAD(P)-binding Rossmann-fold domains    Tyrosine-dependent oxidoreductases    Mannitol dehydrogenase    Mushroom (Agaricus bisporus) GO:  oxidoreductase activity    metabolism    CHAIN: D SWISS-PROT/TREMBL: O93868    KEYWORD: 3D-structure    NADP    Oxidoreductase    EC: 1.1.1.138 SCOP: c.2.1.2 Alpha and beta proteins (a/b)    NAD(P)-binding Rossmann-fold domains    NAD(P)-binding Rossmann-fold domains    Tyrosine-dependent oxidoreductases    Mannitol dehydrogenase    Mushroom (Agaricus bisporus) GO:  oxidoreductase activity    metabolism    CHAIN: E SWISS-PROT/TREMBL: O93868    KEYWORD: 3D-structure    NADP    Oxidoreductase    EC: 1.1.1.138 SCOP: c.2.1.2 Alpha and beta proteins (a/b)    NAD(P)-binding Rossmann-fold domains    NAD(P)-binding Rossmann-fold domains    Tyrosine-dependent oxidoreductases    Mannitol dehydrogenase    Mushroom (Agaricus bisporus) GO:  oxidoreductase activity    metabolism    CHAIN: F SWISS-PROT/TREMBL: O93868    KEYWORD: 3D-structure    NADP    Oxidoreductase    EC: 1.1.1.138 SCOP: c.2.1.2 Alpha and beta proteins (a/b)    NAD(P)-binding Rossmann-fold domains    NAD(P)-binding Rossmann-fold domains    Tyrosine-dependent oxidoreductases    Mannitol dehydrogenase    Mushroom (Agaricus bisporus) GO:  oxidoreductase activity    metabolism    CHAIN: G SWISS-PROT/TREMBL: O93868    KEYWORD: 3D-structure    NADP    Oxidoreductase    EC: 1.1.1.138 SCOP: c.2.1.2 Alpha and beta proteins (a/b)    NAD(P)-binding Rossmann-fold domains    NAD(P)-binding Rossmann-fold domains    Tyrosine-dependent oxidoreductases    Mannitol dehydrogenase    Mushroom (Agaricus bisporus) GO:  oxidoreductase activity    metabolism    CHAIN: H SWISS-PROT/TREMBL: O93868    KEYWORD: 3D-structure    NADP    Oxidoreductase    EC: 1.1.1.138 SCOP: c.2.1.2 Alpha and beta proteins (a/b)    NAD(P)-binding Rossmann-fold domains    NAD(P)-binding Rossmann-fold domains    Tyrosine-dependent oxidoreductases    Mannitol dehydrogenase    Mushroom (Agaricus bisporus) GO:  oxidoreductase activity    metabolism    CHAIN: I SWISS-PROT/TREMBL: O93868    KEYWORD: 3D-structure    NADP    Oxidoreductase    EC: 1.1.1.138 SCOP: c.2.1.2 Alpha and beta proteins (a/b)    NAD(P)-binding Rossmann-fold domains    NAD(P)-binding Rossmann-fold domains    Tyrosine-dependent oxidoreductases    Mannitol dehydrogenase    Mushroom (Agaricus bisporus) GO:  oxidoreductase activity    metabolism    CHAIN: J SWISS-PROT/TREMBL: O93868    KEYWORD: 3D-structure    NADP    Oxidoreductase    EC: 1.1.1.138 SCOP: c.2.1.2 Alpha and beta proteins (a/b)    NAD(P)-binding Rossmann-fold domains    NAD(P)-binding Rossmann-fold domains    Tyrosine-dependent oxidoreductases    Mannitol dehydrogenase    Mushroom (Agaricus bisporus) GO:  oxidoreductase activity    metabolism    CHAIN: K SWISS-PROT/TREMBL: O93868    KEYWORD: 3D-structure    NADP    Oxidoreductase    EC: 1.1.1.138 SCOP: c.2.1.2 Alpha and beta proteins (a/b)    NAD(P)-binding Rossmann-fold domains    NAD(P)-binding Rossmann-fold domains    Tyrosine-dependent oxidoreductases    Mannitol dehydrogenase    Mushroom (Agaricus bisporus) GO:  oxidoreductase activity    metabolism    CHAIN: L SWISS-PROT/TREMBL: O93868    KEYWORD: 3D-structure    NADP    Oxidoreductase    EC: 1.1.1.138 SCOP: c.2.1.2 Alpha and beta proteins (a/b)    NAD(P)-binding Rossmann-fold domains    NAD(P)-binding Rossmann-fold domains    Tyrosine-dependent oxidoreductases    Mannitol dehydrogenase    Mushroom (Agaricus bisporus) GO:  oxidoreductase activity    metabolism

Image Source: PDB

Loops in ArchDB40 clusters

1h5q_A_157 - HA => SUBCLASS : 2.5.1
1h5q_A_63 - EH => SUBCLASS : 4.1.1
1h5q_A_12 - EH => SUBCLASS : 4.32.1
1h5q_A_90 - EH => SUBCLASS : 14.1.1

Loops in ArchDB95 clusters

1h5q_A_162 - EH => SUBCLASS : 2.2.17
1h5q_A_63 - EH => SUBCLASS : 4.1.1
1h5q_A_12 - EH => SUBCLASS : 4.29.1
1h5q_A_90 - EH => SUBCLASS : 14.1.1
1h5q_A_22 - HE => SUBCLASS : 1.2.1
1h5q_A_48 - HE => SUBCLASS : 1.2.4
1h5q_A_167 - HE => SUBCLASS : 1.2.7
1h5q_A_122 - HE => SUBCLASS : 2.1.1
1h5q_A_122 - HE => SUBCLASS : 3.5.1
1h5q_A_122 - HE => SUBCLASS : 3.5.4
1h5q_A_234 - HE => SUBCLASS : 9.1.1
1h5q_A_157 - HA => SUBCLASS : 2.4.2

Loops in ArchDB-EC clusters

1h5q_A_234 - HE => SUBCLASS : 9.1.1

Loops not clustered in ArchDB

1h5q_A_142 - AR
1h5q_A_142 - AR
1h5q_A_36 - EH
1h5q_A_192 - EH
1h5q_A_157 - HA
1h5q_A_73 - HE
1h5q_A_110 - HH
1h5q_A_212 - HH

1h5q A - percentage of sequence identity: 100
1h5q B - percentage of sequence identity: 100
1h5q C - percentage of sequence identity: 100
1h5q D - percentage of sequence identity: 100
1h5q E - percentage of sequence identity: 100
1h5q F - percentage of sequence identity: 100
1h5q G - percentage of sequence identity: 100
1h5q H - percentage of sequence identity: 100
1h5q I - percentage of sequence identity: 100
1h5q J - percentage of sequence identity: 100
1h5q K - percentage of sequence identity: 100
1h5q L - percentage of sequence identity: 100