ArchDB - Biological DataBase of Protein Loops

Information on 1h8d

PDB: 1h8d
Compound: thrombin
Classification: SERINE PROTEASE
Entry date in PDB: 2001-02-26
Resolution [Å]: 1.40
R-Factor: 0.170

CHAIN: H

SWISS-PROT/TREMBL: P00734
   KEYWORD: 3D-structure    Acute phase    Blood coagulation    Calcium-binding    Disease mutation    Gamma-carboxyglutamic acid    Glycoprotein    Hydrolase    Kringle    Plasma    Polymorphism    Repeat    Serine protease    Signal    Vitamin K    Zymogen
EC: 3.4.21.5
SCOP: b.47.1.2 All beta proteins    Trypsin-like serine proteases    Trypsin-like serine proteases    Eukaryotic proteases    Thrombin    Human (Homo sapiens)
GO:  extracellular region    calcium ion binding    chymotrypsin activity    thrombin activity    trypsin activity    blood coagulation    proteolysis and peptidolysis

CHAIN: I

SWISS-PROT/TREMBL: P01050
KEYWORD: 3D-structure Multigene family Pharmaceutical Serine protease inhibitor Sulfation
GO: serine-type endopeptidase inhibitor activity

CHAIN: L

Image Source: PDB

Stored Loops of 1h8d

Loops in ArchDB40 clusters

1h8d_H_198 - HA => SUBCLASS : 4.1.2
1h8d_H_60 - HA => SUBCLASS : 4.1.5
1h8d_H_38 - HA => SUBCLASS : 4.3.2
1h8d_H_198 - HA => SUBCLASS : 6.1.2
1h8d_H_226 - EH => SUBCLASS : 0.1.4
1h8d_H_156 - EH => SUBCLASS : 3.3.3
1h8d_H_20 - AR => SUBCLASS : 8.4.1

Loops in ArchDB95 clusters

1h8d_H_226 - EH => SUBCLASS : 0.1.2
1h8d_H_156 - EH => SUBCLASS : 3.1.3
1h8d_H_156 - EH => SUBCLASS : 3.1.4
1h8d_H_104 - EH => SUBCLASS : 17.3.1
1h8d_H_20 - AR => SUBCLASS : 8.3.1
1h8d_H_180 - AR => SUBCLASS : 19.1.1
1h8d_H_60 - HA => SUBCLASS : 4.1.7
1h8d_H_38 - HA => SUBCLASS : 4.2.1
1h8d_H_198 - HA => SUBCLASS : 6.2.1

Loops in ArchDB-EC clusters

1h8d_H_165 - HE => SUBCLASS : 8.4.1

Loops not clustered in ArchDB

1h8d_H_51 - AR
1h8d_H_51 - AR
1h8d_H_180 - AR
1h8d_H_81 - AR
1h8d_H_20 - AR
1h8d_H_81 - AR
1h8d_H_60 - HA
1h8d_H_64 - HA
1h8d_H_85 - HA
1h8d_H_135 - HA
1h8d_H_198 - HA
1h8d_H_207 - HA
1h8d_H_38 - HA
1h8d_H_30 - HA
1h8d_H_207 - HA
1h8d_H_135 - HA
1h8d_H_85 - HA
1h8d_H_64 - HA
1h8d_H_30 - HA
1h8d_H_126 - HE

Homologous structures to 1h8d classified in ArchDB

1a0h B - percentage of sequence identity: 86
1a0h E - percentage of sequence identity: 86
1a2c H - percentage of sequence identity: 97
1a3b H - percentage of sequence identity: 97
1a3e H - percentage of sequence identity: 97
1a46 H - percentage of sequence identity: 97
1a4w H - percentage of sequence identity: 97
1a5g H - percentage of sequence identity: 97
1a61 H - percentage of sequence identity: 97
1abi H - percentage of sequence identity: 97
1abj H - percentage of sequence identity: 97
1ad8 H - percentage of sequence identity: 97
1ae8 H - percentage of sequence identity: 97
1afe H - percentage of sequence identity: 97
1aht H - percentage of sequence identity: 97
1ai8 H - percentage of sequence identity: 97
1aix H - percentage of sequence identity: 97
1avg H - percentage of sequence identity: 86
1awf H - percentage of sequence identity: 97
1awh B - percentage of sequence identity: 97
1awh D - percentage of sequence identity: 97
1ay6 H - percentage of sequence identity: 97
1b5g H - percentage of sequence identity: 97
1b7x B - percentage of sequence identity: 96
1ba8 B - percentage of sequence identity: 97
1bb0 B - percentage of sequence identity: 97
1bbr E - percentage of sequence identity: 94
1bbr H - percentage of sequence identity: 85
1bbr K - percentage of sequence identity: 86
1bbr N - percentage of sequence identity: 86
1bcu H - percentage of sequence identity: 97
1bhx B - percentage of sequence identity: 100
1bhx F - percentage of sequence identity: 100
1bmm H - percentage of sequence identity: 97
1bmn H - percentage of sequence identity: 97
1bth H - percentage of sequence identity: 96
1bth K - percentage of sequence identity: 96
1c1u H - percentage of sequence identity: 97
1c1v H - percentage of sequence identity: 97
1c1w H - percentage of sequence identity: 97
1c4u 2 - percentage of sequence identity: 97
1c4v 2 - percentage of sequence identity: 97
1c4y 2 - percentage of sequence identity: 97
1c5l H - percentage of sequence identity: 97
1c5n H - percentage of sequence identity: 97
1c5o H - percentage of sequence identity: 97
1ca8 B - percentage of sequence identity: 97
1d3d B - percentage of sequence identity: 97
1d3p B - percentage of sequence identity: 97
1d3q B - percentage of sequence identity: 97
1d3t B - percentage of sequence identity: 97
1d4p B - percentage of sequence identity: 97
1d6w A - percentage of sequence identity: 97
1d9i A - percentage of sequence identity: 97
1de7 H - percentage of sequence identity: 97
1de7 K - percentage of sequence identity: 97
1dit H - percentage of sequence identity: 97
1dm4 B - percentage of sequence identity: 96
1doj A - percentage of sequence identity: 97
1dwb H - percentage of sequence identity: 97
1dwc H - percentage of sequence identity: 97
1dwd H - percentage of sequence identity: 97
1dwe H - percentage of sequence identity: 97
1dx5 M - percentage of sequence identity: 96
1dx5 N - percentage of sequence identity: 96
1dx5 O - percentage of sequence identity: 96
1dx5 P - percentage of sequence identity: 96
1e0f D - percentage of sequence identity: 96
1e0f E - percentage of sequence identity: 96
1e0f F - percentage of sequence identity: 96
1eb1 H - percentage of sequence identity: 97
1eoj A - percentage of sequence identity: 97
1eol A - percentage of sequence identity: 97
1ets H - percentage of sequence identity: 86
1ett H - percentage of sequence identity: 86
1fpc H - percentage of sequence identity: 97
1fph H - percentage of sequence identity: 97
1g30 B - percentage of sequence identity: 97
1g32 B - percentage of sequence identity: 97
1g37 A - percentage of sequence identity: 97
1ghv H - percentage of sequence identity: 97
1ghw H - percentage of sequence identity: 97
1ghx H - percentage of sequence identity: 97
1ghy H - percentage of sequence identity: 97
1gj4 H - percentage of sequence identity: 97
1gj5 H - percentage of sequence identity: 97
1h8i H - percentage of sequence identity: 99
1hag E - percentage of sequence identity: 97
1hah H - percentage of sequence identity: 97
1hai H - percentage of sequence identity: 97
1hao H - percentage of sequence identity: 97
1hap H - percentage of sequence identity: 97
1hbt H - percentage of sequence identity: 97
1hdt H - percentage of sequence identity: 97
1hgt H - percentage of sequence identity: 97
1hlt H - percentage of sequence identity: 97
1hlt K - percentage of sequence identity: 97
1hrt H - percentage of sequence identity: 86
1hut H - percentage of sequence identity: 97
1hxe H - percentage of sequence identity: 97
1hxf H - percentage of sequence identity: 97
1id5 H - percentage of sequence identity: 86
1ihs H - percentage of sequence identity: 97
1iht H - percentage of sequence identity: 97
1jmo H - percentage of sequence identity: 96
1jou D - percentage of sequence identity: 96
1jou F - percentage of sequence identity: 96
1jwt A - percentage of sequence identity: 97
1k21 H - percentage of sequence identity: 97
1k22 H - percentage of sequence identity: 97
1kts B - percentage of sequence identity: 97
1ktt B - percentage of sequence identity: 97
1lhc H - percentage of sequence identity: 97
1lhd H - percentage of sequence identity: 97
1lhe H - percentage of sequence identity: 97
1lhf H - percentage of sequence identity: 97
1lhg H - percentage of sequence identity: 97
1mh0 A - percentage of sequence identity: 96
1mh0 B - percentage of sequence identity: 96
1mkw H - percentage of sequence identity: 86
1mkw K - percentage of sequence identity: 86
1mkx H - percentage of sequence identity: 86
1mkx K - percentage of sequence identity: 86
1mu6 B - percentage of sequence identity: 97
1mu8 B - percentage of sequence identity: 97
1mue B - percentage of sequence identity: 97
1nm6 A - percentage of sequence identity: 97
1no9 H - percentage of sequence identity: 97
1nrn H - percentage of sequence identity: 97
1nro H - percentage of sequence identity: 97
1nrp H - percentage of sequence identity: 97
1nrq H - percentage of sequence identity: 97
1nrr H - percentage of sequence identity: 97
1nrs H - percentage of sequence identity: 97
1nt1 A - percentage of sequence identity: 97
1nu7 B - percentage of sequence identity: 97
1nu7 F - percentage of sequence identity: 97
1nu9 A - percentage of sequence identity: 97
1nu9 D - percentage of sequence identity: 97
1ny2 2 - percentage of sequence identity: 97
1nzq H - percentage of sequence identity: 97
1o0d H - percentage of sequence identity: 97
1o2g H - percentage of sequence identity: 97
1o5g H - percentage of sequence identity: 97
1ook B - percentage of sequence identity: 97
1oyt H - percentage of sequence identity: 97
1p8v C - percentage of sequence identity: 97
1ppb H - percentage of sequence identity: 97
1qbv H - percentage of sequence identity: 97
1qhr B - percentage of sequence identity: 97
1qj1 B - percentage of sequence identity: 97
1qj6 B - percentage of sequence identity: 97
1qj7 B - percentage of sequence identity: 97
1qur H - percentage of sequence identity: 97
1qvh B - percentage of sequence identity: 97
1qvh E - percentage of sequence identity: 97
1rd3 B - percentage of sequence identity: 96
1rd3 D - percentage of sequence identity: 96
1riw B - percentage of sequence identity: 100
1riw C - percentage of sequence identity: 100
1sb1 H - percentage of sequence identity: 97
1sfq B - percentage of sequence identity: 96
1sfq E - percentage of sequence identity: 96
1sg8 B - percentage of sequence identity: 96
1sg8 E - percentage of sequence identity: 96
1sgi B - percentage of sequence identity: 96
1sgi E - percentage of sequence identity: 96
1shh B - percentage of sequence identity: 96
1shh E - percentage of sequence identity: 96
1sl3 A - percentage of sequence identity: 97
1sr5 C - percentage of sequence identity: 97
1t4u H - percentage of sequence identity: 97
1t4v H - percentage of sequence identity: 97
1ta2 A - percentage of sequence identity: 97
1ta6 A - percentage of sequence identity: 97
1tb6 H - percentage of sequence identity: 96
1tbq H - percentage of sequence identity: 86
1tbq K - percentage of sequence identity: 86
1tbr H - percentage of sequence identity: 86
1tbr K - percentage of sequence identity: 86
1tbz H - percentage of sequence identity: 97
1thp B - percentage of sequence identity: 96
1thr H - percentage of sequence identity: 97
1ths H - percentage of sequence identity: 97
1tmb H - percentage of sequence identity: 97
1tmt H - percentage of sequence identity: 97
1tmu H - percentage of sequence identity: 97
1toc B - percentage of sequence identity: 86
1toc D - percentage of sequence identity: 86
1toc F - percentage of sequence identity: 86
1toc H - percentage of sequence identity: 86
1tom H - percentage of sequence identity: 97
1tq0 B - percentage of sequence identity: 96
1tq0 D - percentage of sequence identity: 96
1tq7 B - percentage of sequence identity: 96
1twx B - percentage of sequence identity: 96
1ucy E - percentage of sequence identity: 94
1ucy K - percentage of sequence identity: 86
1ucy N - percentage of sequence identity: 86
1uma H - percentage of sequence identity: 97
1uvs H - percentage of sequence identity: 97
1uvt H - percentage of sequence identity: 86
1uvu H - percentage of sequence identity: 86
1vit F - percentage of sequence identity: 85
1vit G - percentage of sequence identity: 94
1vit H - percentage of sequence identity: 86
1vzq H - percentage of sequence identity: 99
1way B - percentage of sequence identity: 97
1wbg B - percentage of sequence identity: 96
1xm1 A - percentage of sequence identity: 97
1xmn B - percentage of sequence identity: 97
1xmn D - percentage of sequence identity: 97
1xmn F - percentage of sequence identity: 97
1xmn H - percentage of sequence identity: 97
1ycp H - percentage of sequence identity: 86
1ycp K - percentage of sequence identity: 85
1ycp M - percentage of sequence identity: 94
1ype H - percentage of sequence identity: 97
1ypg H - percentage of sequence identity: 97
1ypj H - percentage of sequence identity: 97
1ypk H - percentage of sequence identity: 97
1ypl H - percentage of sequence identity: 97
1ypm H - percentage of sequence identity: 97
1z71 A - percentage of sequence identity: 97
1z8i B - percentage of sequence identity: 96
1z8j B - percentage of sequence identity: 96
1zgi A - percentage of sequence identity: 97
1zgv A - percentage of sequence identity: 97
1zrb A - percentage of sequence identity: 97
2a0q B - percentage of sequence identity: 96
2a0q D - percentage of sequence identity: 96
2a1d B - percentage of sequence identity: 86
2a1d F - percentage of sequence identity: 86
2afq B - percentage of sequence identity: 97
2afq D - percentage of sequence identity: 97
2hgt H - percentage of sequence identity: 97
2hnt C - percentage of sequence identity: 100
2hnt E - percentage of sequence identity: 94
2hpp H - percentage of sequence identity: 97
2hpq H - percentage of sequence identity: 97
2thf B - percentage of sequence identity: 96
3hat H - percentage of sequence identity: 97
3htc H - percentage of sequence identity: 97
4htc H - percentage of sequence identity: 97
4thn H - percentage of sequence identity: 97
5gds H - percentage of sequence identity: 97
7kme H - percentage of sequence identity: 97
8kme 2 - percentage of sequence identity: 97
null nu - percentage of sequence identity: 0