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Information on 1h8i
PDB: 1h8i
Compound: thrombin
Classification: SERINE PROTEASE
Entry date in PDB: 2001-03-02
Resolution [Å]: 1.75
R-Factor: 0.186


CHAIN: H
SWISS-PROT/TREMBL: P00734
   KEYWORD: 3D-structure    Acute phase    Blood coagulation    Calcium-binding    Disease mutation    Gamma-carboxyglutamic acid    Glycoprotein    Hydrolase    Kringle    Plasma    Polymorphism    Repeat    Serine protease    Signal    Vitamin K    Zymogen   
EC: 3.4.21.5
SCOP: b.47.1.2 All beta proteins    Trypsin-like serine proteases    Trypsin-like serine proteases    Eukaryotic proteases    Thrombin    Human (Homo sapiens)
GO:  extracellular region    calcium ion binding    chymotrypsin activity    thrombin activity    trypsin activity    blood coagulation    proteolysis and peptidolysis   


CHAIN: I
SWISS-PROT/TREMBL: P01050
   KEYWORD: 3D-structure    Multigene family    Pharmaceutical    Serine protease inhibitor    Sulfation   
GO:  serine-type endopeptidase inhibitor activity   


CHAIN: L
SWISS-PROT/TREMBL: P00734
   KEYWORD: 3D-structure    Acute phase    Blood coagulation    Calcium-binding    Disease mutation    Gamma-carboxyglutamic acid    Glycoprotein    Hydrolase    Kringle    Plasma    Polymorphism    Repeat    Serine protease    Signal    Vitamin K    Zymogen   
EC: 3.4.21.5
SCOP: b.47.1.2 All beta proteins    Trypsin-like serine proteases    Trypsin-like serine proteases    Eukaryotic proteases    Thrombin    Human (Homo sapiens)
GO:  extracellular region    calcium ion binding    chymotrypsin activity    thrombin activity    trypsin activity    blood coagulation    proteolysis and peptidolysis   
1h8i Image
Image Source: PDB
Homologous structures to 1h8i classified in ArchDB

1etr H - percentage of sequence identity: 86
1h8d H - percentage of sequence identity: 99
1jou B - percentage of sequence identity: 97
1ucy H - percentage of sequence identity: 85
1vr1 H - percentage of sequence identity: 94
2hnt F - percentage of sequence identity: 100
null nu - percentage of sequence identity: 0