PDB: 1hdr Compound: Dihydropteridine reductase (dhpr) complexed with n Classification: OXIDOREDUCTASE(ACTING ON NADH) Entry date in PDB: 1994-08-31 Resolution [Å]: 2.50 R-Factor: 0.169

CHAIN: - SWISS-PROT/TREMBL: P09417    KEYWORD: 3D-structure    Disease mutation    NADP    Oxidoreductase    Phenylketonuria    Polymorphism    Tetrahydrobiopterin biosynthesis    EC: 1.5.1.34 SCOP: c.2.1.2 Alpha and beta proteins (a/b)    NAD(P)-binding Rossmann-fold domains    NAD(P)-binding Rossmann-fold domains    Tyrosine-dependent oxidoreductases    Dihydropteridin reductase (pteridine reductase)    Human (Homo sapiens) GO:  oxidoreductase activity    metabolism

Image Source: PDB

Loops in ArchDB95 clusters

1hdr_*_49 - EH => SUBCLASS : 4.3.2
1hdr_*_11 - EH => SUBCLASS : 4.7.1
1hdr_*_124 - EH => SUBCLASS : 9.8.1
1hdr_*_20 - HE => SUBCLASS : 1.1.1
1hdr_*_59 - HE => SUBCLASS : 3.24.1
1hdr_*_59 - HE => SUBCLASS : 4.26.1
1hdr_*_226 - HA => SUBCLASS : 2.1.1

Loops not clustered in ArchDB

1hdr_*_79 - EH
1hdr_*_175 - EH
1hdr_*_35 - HA
1hdr_*_111 - HE
1hdr_*_147 - HE
1hdr_*_204 - HE
1hdr_*_99 - HH
1hdr_*_187 - HH

1dir A - percentage of sequence identity: 95
1dir B - percentage of sequence identity: 95
1dir C - percentage of sequence identity: 95
1dir D - percentage of sequence identity: 95