PDB: 1hfc Compound: Fibroblast collagenase Classification: METALLOPROTEASE Entry date in PDB: 1995-01-26 Resolution [Å]: 1.56 R-Factor: 0.174

CHAIN: - SWISS-PROT/TREMBL: P03956    KEYWORD: 3D-structure    Autocatalytic cleavage    Calcium-binding    Collagen degradation    Extracellular matrix    Glycoprotein    Hydrolase    Metal-binding    Metalloprotease    Polymorphism    Signal    Zinc    Zymogen    EC: 3.4.24.7 SCOP: d.92.1.11 Alpha and beta proteins (a+b)    Zincin-like    Metalloproteases ("zincins"), catalytic domain    Matrix metalloproteases, catalytic domain    Fibroblast collagenase (MMP-1)    Human (Homo sapiens) GO:  extracellular matrix (sensu Metazoa)    metalloendopeptidase activity    metallopeptidase activity    zinc ion binding    proteolysis and peptidolysis

Image Source: PDB

Loops in ArchDB95 clusters

1hfc_*_113 - EH => SUBCLASS : 5.3.1
1hfc_*_195 - EH => SUBCLASS : 13.8.1
1hfc_*_148 - AR => SUBCLASS : 6.7.1
1hfc_*_159 - AR => SUBCLASS : 16.2.1
1hfc_*_127 - HE => SUBCLASS : 2.2.2
1hfc_*_182 - HA => SUBCLASS : 9.3.1

Loops in ArchDB-EC clusters

1hfc_*_127 - HE => SUBCLASS : 3.8.1

Loops not clustered in ArchDB

1hfc_*_148 - AR
1hfc_*_159 - AR
1hfc_*_182 - HA
1hfc_*_212 - HH

1a85 A - percentage of sequence identity: 66
1a86 A - percentage of sequence identity: 66
1ayk - - percentage of sequence identity: 100
1b3d A - percentage of sequence identity: 61
1b3d B - percentage of sequence identity: 61
1b8y A - percentage of sequence identity: 61
1biw A - percentage of sequence identity: 61
1biw B - percentage of sequence identity: 61
1bm6 - - percentage of sequence identity: 61
1bqo A - percentage of sequence identity: 61
1bqo B - percentage of sequence identity: 61
1bzs A - percentage of sequence identity: 66
1c3i A - percentage of sequence identity: 61
1c3i B - percentage of sequence identity: 61
1caq A - percentage of sequence identity: 61
1cge - - percentage of sequence identity: 99
1cgf A - percentage of sequence identity: 99
1cgf B - percentage of sequence identity: 99
1cgl B - percentage of sequence identity: 98
1ciz A - percentage of sequence identity: 61
1cqr A - percentage of sequence identity: 61
1cqr B - percentage of sequence identity: 61
1cxv B - percentage of sequence identity: 60
1d5j A - percentage of sequence identity: 61
1d5j B - percentage of sequence identity: 61
1d7x A - percentage of sequence identity: 61
1d7x B - percentage of sequence identity: 61
1d8f A - percentage of sequence identity: 61
1d8f B - percentage of sequence identity: 61
1d8m A - percentage of sequence identity: 61
1d8m B - percentage of sequence identity: 61
1g05 A - percentage of sequence identity: 61
1g05 B - percentage of sequence identity: 61
1g49 A - percentage of sequence identity: 61
1g49 B - percentage of sequence identity: 61
1g4k A - percentage of sequence identity: 61
1g4k B - percentage of sequence identity: 61
1g4k C - percentage of sequence identity: 61
1hfs - - percentage of sequence identity: 61
1hy7 B - percentage of sequence identity: 61
1i73 A - percentage of sequence identity: 66
1jan A - percentage of sequence identity: 66
1jao A - percentage of sequence identity: 66
1jap A - percentage of sequence identity: 66
1jaq A - percentage of sequence identity: 66
1jh1 A - percentage of sequence identity: 66
1jj9 A - percentage of sequence identity: 66
1kbc A - percentage of sequence identity: 66
1kbc B - percentage of sequence identity: 66
1mmb - - percentage of sequence identity: 66
1mnc - - percentage of sequence identity: 65
1oo9 A - percentage of sequence identity: 61
1q3a B - percentage of sequence identity: 61
1q3a C - percentage of sequence identity: 61
1qia A - percentage of sequence identity: 61
1qia B - percentage of sequence identity: 61
1qia C - percentage of sequence identity: 61
1qia D - percentage of sequence identity: 61
1qic A - percentage of sequence identity: 61
1qic B - percentage of sequence identity: 61
1qic C - percentage of sequence identity: 61
1qic D - percentage of sequence identity: 61
1sln - - percentage of sequence identity: 61
1su3 A - percentage of sequence identity: 100
1su3 B - percentage of sequence identity: 100
1uea A - percentage of sequence identity: 61
1uea C - percentage of sequence identity: 61
1ums A - percentage of sequence identity: 61
1umt A - percentage of sequence identity: 61
1usn - - percentage of sequence identity: 61
1zp5 A - percentage of sequence identity: 66
2ayk - - percentage of sequence identity: 100
2srt - - percentage of sequence identity: 61
2tcl - - percentage of sequence identity: 100
2usn - - percentage of sequence identity: 61
3ayk A - percentage of sequence identity: 100
3usn - - percentage of sequence identity: 61
4ayk A - percentage of sequence identity: 100
966c - - percentage of sequence identity: 100