PDB: 1hkx Compound: calciumCALMODULIN-DEPENDENT PROTEIN KINASE TYPE ii Classification: TRANSFERASE Entry date in PDB: 2003-06-02 Resolution [Å]: 2.65 R-Factor: 0.246

CHAIN: A SWISS-PROT/TREMBL: P11798    KEYWORD: 3D-structure    Alternative splicing    ATP-binding    Calmodulin-binding    Phosphorylation    Serine/threonine-protein kinase    Transferase    3D-structure    Alternative splicing    ATP-binding    Calmodulin-binding    Phosphorylation    Serine/threonine-protein kinase    Transferase    EC: 2.7.1.123 SCOP: d.17.4.7 Alpha and beta proteins (a+b)    Cystatin-like    NTF2-like    Association domain of calcium/calmodulin-dependent protein kinase type II alpha subunit, CAMK2A    Association domain of calcium/calmodulin-dependent protein kinase type II alpha subunit, CAMK2A    Mouse (Mus musculus) GO:  ATP binding    protein kinase activity    protein serine/threonine kinase activity    protein amino acid phosphorylation    CHAIN: B SWISS-PROT/TREMBL: P11798    KEYWORD: 3D-structure    Alternative splicing    ATP-binding    Calmodulin-binding    Phosphorylation    Serine/threonine-protein kinase    Transferase    EC: 2.7.1.123 SCOP: d.17.4.7 Alpha and beta proteins (a+b)    Cystatin-like    NTF2-like    Association domain of calcium/calmodulin-dependent protein kinase type II alpha subunit, CAMK2A    Association domain of calcium/calmodulin-dependent protein kinase type II alpha subunit, CAMK2A    Mouse (Mus musculus) GO:  ATP binding    protein kinase activity    protein serine/threonine kinase activity    protein amino acid phosphorylation    CHAIN: C SWISS-PROT/TREMBL: P11798    KEYWORD: 3D-structure    Alternative splicing    ATP-binding    Calmodulin-binding    Phosphorylation    Serine/threonine-protein kinase    Transferase    EC: 2.7.1.123 SCOP: d.17.4.7 Alpha and beta proteins (a+b)    Cystatin-like    NTF2-like    Association domain of calcium/calmodulin-dependent protein kinase type II alpha subunit, CAMK2A    Association domain of calcium/calmodulin-dependent protein kinase type II alpha subunit, CAMK2A    Mouse (Mus musculus) GO:  ATP binding    protein kinase activity    protein serine/threonine kinase activity    protein amino acid phosphorylation    CHAIN: D SWISS-PROT/TREMBL: P11798    KEYWORD: 3D-structure    Alternative splicing    ATP-binding    Calmodulin-binding    Phosphorylation    Serine/threonine-protein kinase    Transferase    EC: 2.7.1.123 SCOP: d.17.4.7 Alpha and beta proteins (a+b)    Cystatin-like    NTF2-like    Association domain of calcium/calmodulin-dependent protein kinase type II alpha subunit, CAMK2A    Association domain of calcium/calmodulin-dependent protein kinase type II alpha subunit, CAMK2A    Mouse (Mus musculus) GO:  ATP binding    protein kinase activity    protein serine/threonine kinase activity    protein amino acid phosphorylation    CHAIN: E SWISS-PROT/TREMBL: P11798    KEYWORD: 3D-structure    Alternative splicing    ATP-binding    Calmodulin-binding    Phosphorylation    Serine/threonine-protein kinase    Transferase    3D-structure    Alternative splicing    ATP-binding    Calmodulin-binding    Phosphorylation    Serine/threonine-protein kinase    Transferase    EC: 2.7.1.123 SCOP: d.17.4.7 Alpha and beta proteins (a+b)    Cystatin-like    NTF2-like    Association domain of calcium/calmodulin-dependent protein kinase type II alpha subunit, CAMK2A    Association domain of calcium/calmodulin-dependent protein kinase type II alpha subunit, CAMK2A    Mouse (Mus musculus) GO:  ATP binding    protein kinase activity    protein serine/threonine kinase activity    protein amino acid phosphorylation    CHAIN: F SWISS-PROT/TREMBL: P11798    KEYWORD: 3D-structure    Alternative splicing    ATP-binding    Calmodulin-binding    Phosphorylation    Serine/threonine-protein kinase    Transferase    EC: 2.7.1.123 SCOP: d.17.4.7 Alpha and beta proteins (a+b)    Cystatin-like    NTF2-like    Association domain of calcium/calmodulin-dependent protein kinase type II alpha subunit, CAMK2A    Association domain of calcium/calmodulin-dependent protein kinase type II alpha subunit, CAMK2A    Mouse (Mus musculus) GO:  ATP binding    protein kinase activity    protein serine/threonine kinase activity    protein amino acid phosphorylation    CHAIN: G SWISS-PROT/TREMBL: P11798    KEYWORD: 3D-structure    Alternative splicing    ATP-binding    Calmodulin-binding    Phosphorylation    Serine/threonine-protein kinase    Transferase    EC: 2.7.1.123 SCOP: d.17.4.7 Alpha and beta proteins (a+b)    Cystatin-like    NTF2-like    Association domain of calcium/calmodulin-dependent protein kinase type II alpha subunit, CAMK2A    Association domain of calcium/calmodulin-dependent protein kinase type II alpha subunit, CAMK2A    Mouse (Mus musculus) GO:  ATP binding    protein kinase activity    protein serine/threonine kinase activity    protein amino acid phosphorylation    CHAIN: H SWISS-PROT/TREMBL: P11798    KEYWORD: 3D-structure    Alternative splicing    ATP-binding    Calmodulin-binding    Phosphorylation    Serine/threonine-protein kinase    Transferase    3D-structure    Alternative splicing    ATP-binding    Calmodulin-binding    Phosphorylation    Serine/threonine-protein kinase    Transferase    EC: 2.7.1.123 SCOP: d.17.4.7 Alpha and beta proteins (a+b)    Cystatin-like    NTF2-like    Association domain of calcium/calmodulin-dependent protein kinase type II alpha subunit, CAMK2A    Association domain of calcium/calmodulin-dependent protein kinase type II alpha subunit, CAMK2A    Mouse (Mus musculus) GO:  ATP binding    protein kinase activity    protein serine/threonine kinase activity    protein amino acid phosphorylation    CHAIN: I SWISS-PROT/TREMBL: P11798    KEYWORD: 3D-structure    Alternative splicing    ATP-binding    Calmodulin-binding    Phosphorylation    Serine/threonine-protein kinase    Transferase    EC: 2.7.1.123 SCOP: d.17.4.7 Alpha and beta proteins (a+b)    Cystatin-like    NTF2-like    Association domain of calcium/calmodulin-dependent protein kinase type II alpha subunit, CAMK2A    Association domain of calcium/calmodulin-dependent protein kinase type II alpha subunit, CAMK2A    Mouse (Mus musculus) GO:  ATP binding    protein kinase activity    protein serine/threonine kinase activity    protein amino acid phosphorylation    CHAIN: J SWISS-PROT/TREMBL: P11798    KEYWORD: 3D-structure    Alternative splicing    ATP-binding    Calmodulin-binding    Phosphorylation    Serine/threonine-protein kinase    Transferase    EC: 2.7.1.123 SCOP: d.17.4.7 Alpha and beta proteins (a+b)    Cystatin-like    NTF2-like    Association domain of calcium/calmodulin-dependent protein kinase type II alpha subunit, CAMK2A    Association domain of calcium/calmodulin-dependent protein kinase type II alpha subunit, CAMK2A    Mouse (Mus musculus) GO:  ATP binding    protein kinase activity    protein serine/threonine kinase activity    protein amino acid phosphorylation    CHAIN: K SWISS-PROT/TREMBL: P11798    KEYWORD: 3D-structure    Alternative splicing    ATP-binding    Calmodulin-binding    Phosphorylation    Serine/threonine-protein kinase    Transferase    EC: 2.7.1.123 SCOP: d.17.4.7 Alpha and beta proteins (a+b)    Cystatin-like    NTF2-like    Association domain of calcium/calmodulin-dependent protein kinase type II alpha subunit, CAMK2A    Association domain of calcium/calmodulin-dependent protein kinase type II alpha subunit, CAMK2A    Mouse (Mus musculus) GO:  ATP binding    protein kinase activity    protein serine/threonine kinase activity    protein amino acid phosphorylation    CHAIN: L SWISS-PROT/TREMBL: P11798    KEYWORD: 3D-structure    Alternative splicing    ATP-binding    Calmodulin-binding    Phosphorylation    Serine/threonine-protein kinase    Transferase    EC: 2.7.1.123 SCOP: d.17.4.7 Alpha and beta proteins (a+b)    Cystatin-like    NTF2-like    Association domain of calcium/calmodulin-dependent protein kinase type II alpha subunit, CAMK2A    Association domain of calcium/calmodulin-dependent protein kinase type II alpha subunit, CAMK2A    Mouse (Mus musculus) GO:  ATP binding    protein kinase activity    protein serine/threonine kinase activity    protein amino acid phosphorylation    CHAIN: M SWISS-PROT/TREMBL: P11798    KEYWORD: 3D-structure    Alternative splicing    ATP-binding    Calmodulin-binding    Phosphorylation    Serine/threonine-protein kinase    Transferase    EC: 2.7.1.123 SCOP: d.17.4.7 Alpha and beta proteins (a+b)    Cystatin-like    NTF2-like    Association domain of calcium/calmodulin-dependent protein kinase type II alpha subunit, CAMK2A    Association domain of calcium/calmodulin-dependent protein kinase type II alpha subunit, CAMK2A    Mouse (Mus musculus) GO:  ATP binding    protein kinase activity    protein serine/threonine kinase activity    protein amino acid phosphorylation    CHAIN: N SWISS-PROT/TREMBL: P11798    KEYWORD: 3D-structure    Alternative splicing    ATP-binding    Calmodulin-binding    Phosphorylation    Serine/threonine-protein kinase    Transferase    EC: 2.7.1.123 SCOP: d.17.4.7 Alpha and beta proteins (a+b)    Cystatin-like    NTF2-like    Association domain of calcium/calmodulin-dependent protein kinase type II alpha subunit, CAMK2A    Association domain of calcium/calmodulin-dependent protein kinase type II alpha subunit, CAMK2A    Mouse (Mus musculus) GO:  ATP binding    protein kinase activity    protein serine/threonine kinase activity    protein amino acid phosphorylation

Image Source: PDB

Loops in ArchDB-EC clusters

1hkx_A_341 - HH => SUBCLASS : 2.2.1

Loops not clustered in ArchDB

1hkx_A_389 - EH
1hkx_A_372 - HA
1hkx_A_410 - HA
1hkx_A_426 - HA
1hkx_A_445 - HA
1hkx_A_366 - HE
1hkx_A_393 - HE

1hkx A - percentage of sequence identity: 100
1hkx B - percentage of sequence identity: 100
1hkx C - percentage of sequence identity: 100
1hkx D - percentage of sequence identity: 100
1hkx E - percentage of sequence identity: 100
1hkx F - percentage of sequence identity: 100
1hkx G - percentage of sequence identity: 100
1hkx H - percentage of sequence identity: 100
1hkx I - percentage of sequence identity: 100
1hkx J - percentage of sequence identity: 100
1hkx K - percentage of sequence identity: 100
1hkx L - percentage of sequence identity: 100
1hkx M - percentage of sequence identity: 100
1hkx N - percentage of sequence identity: 100