PDB: 1hpv Compound: Hiv-1 protease complexed with vx-478 (3(s)-n-(3-te Classification: HYDROLASE (ACID PROTEINASE) Entry date in PDB: 1995-03-31 Resolution [Å]: 1.90 R-Factor: 0.192

CHAIN: A SWISS-PROT/TREMBL: P04587    KEYWORD: 3D-structure    AIDS    Aspartyl protease    Endonuclease    Hydrolase    Metal-binding    Nuclease    Polyprotein    RNA-directed DNA polymerase    Transferase    Zinc    Zinc-finger    EC: 2.7.7.49 SCOP: b.50.1.1 All beta proteins    Acid proteases    Acid proteases    Retroviral protease (retropepsin)    Human immunodeficiency virus type 1 protease    Human immunodeficiency virus type 1 GO:  aspartic-type endopeptidase activity    DNA binding    integrase activity    nucleic acid binding    ribonuclease H activity    RNA binding    RNA-directed DNA polymerase activity    zinc ion binding    DNA integration    DNA recombination    proteolysis and peptidolysis    RNA-dependent DNA replication    CHAIN: B SWISS-PROT/TREMBL: P04587    KEYWORD: 3D-structure    AIDS    Aspartyl protease    Endonuclease    Hydrolase    Metal-binding    Nuclease    Polyprotein    RNA-directed DNA polymerase    Transferase    Zinc    Zinc-finger    EC: 2.7.7.49 SCOP: b.50.1.1 All beta proteins    Acid proteases    Acid proteases    Retroviral protease (retropepsin)    Human immunodeficiency virus type 1 protease    Human immunodeficiency virus type 1 GO:  aspartic-type endopeptidase activity    DNA binding    integrase activity    nucleic acid binding    ribonuclease H activity    RNA binding    RNA-directed DNA polymerase activity    zinc ion binding    DNA integration    DNA recombination    proteolysis and peptidolysis    RNA-dependent DNA replication

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1bdq A - percentage of sequence identity: 90
1c6y A - percentage of sequence identity: 90
1hvc - - percentage of sequence identity: 96
1kzk A - percentage of sequence identity: 93
1nh0 A - percentage of sequence identity: 100