ArchDB - Biological DataBase of Protein Loops

Information on 1hvy

PDB: 1hvy
Compound: thymidylate synthase
Classification: TRANSFERASE
Entry date in PDB: 2001-01-31
Resolution [Å]: 1.90
R-Factor: 0.201

CHAIN: A

SWISS-PROT/TREMBL: P04818
   KEYWORD: 3D-structure    Methyltransferase    Nucleotide biosynthesis    Transferase
EC: 2.1.1.45
SCOP: d.117.1.1 Alpha and beta proteins (a+b)    Thymidylate synthase/dCMP hydroxymethylase    Thymidylate synthase/dCMP hydroxymethylase    Thymidylate synthase/dCMP hydroxymethylase    Thymidylate synthase    Human (Homo sapiens)
GO:  thymidylate synthase activity    dTMP biosynthesis

CHAIN: B

CHAIN: C

CHAIN: D

Image Source: PDB

Stored Loops of 1hvy

Loops in ArchDB95 clusters

1hvy_A_244 - EH => SUBCLASS : 0.1.23
1hvy_A_81 - HH => SUBCLASS : 4.5.1
1hvy_A_135 - HH => SUBCLASS : 18.2.1
1hvy_A_222 - HE => SUBCLASS : 1.2.17
1hvy_A_262 - HE => SUBCLASS : 7.7.1
1hvy_A_160 - HE => SUBCLASS : 7.17.1
1hvy_A_196 - HA => SUBCLASS : 2.1.1
1hvy_A_45 - HA => SUBCLASS : 7.29.1
1hvy_A_178 - HA => SUBCLASS : 15.1.1

Loops in ArchDB-EC clusters

1hvy_A_135 - HH => SUBCLASS : 18.1.1

Loops not clustered in ArchDB

1hvy_A_55 - EH
1hvy_A_207 - EH
1hvy_A_196 - HA
1hvy_A_178 - HA
1hvy_A_45 - HA
1hvy_A_278 - HA
1hvy_A_278 - HA
1hvy_A_30 - HE
1hvy_A_115 - HH
1hvy_A_98 - HH

Homologous structures to 1hvy classified in ArchDB

1ci7 A - percentage of sequence identity: 61
1ci7 B - percentage of sequence identity: 61
1f28 A - percentage of sequence identity: 61
1f28 B - percentage of sequence identity: 61
1f28 C - percentage of sequence identity: 61
1f28 D - percentage of sequence identity: 61
1hvy A - percentage of sequence identity: 100
1hvy B - percentage of sequence identity: 100
1hvy C - percentage of sequence identity: 100
1hvy D - percentage of sequence identity: 100
1hw3 A - percentage of sequence identity: 100
1hw4 A - percentage of sequence identity: 100
1hzw A - percentage of sequence identity: 100
1hzw B - percentage of sequence identity: 100
1i00 A - percentage of sequence identity: 100
1i00 B - percentage of sequence identity: 100
1ju6 A - percentage of sequence identity: 99
1ju6 B - percentage of sequence identity: 99
1ju6 C - percentage of sequence identity: 99
1ju6 D - percentage of sequence identity: 99
1juj A - percentage of sequence identity: 99
1juj B - percentage of sequence identity: 99
1juj C - percentage of sequence identity: 99
1juj D - percentage of sequence identity: 99
1rts A - percentage of sequence identity: 92
1rts B - percentage of sequence identity: 92
1ypv A - percentage of sequence identity: 100
2aaz A - percentage of sequence identity: 61
2aaz B - percentage of sequence identity: 61
2aaz C - percentage of sequence identity: 61
2aaz D - percentage of sequence identity: 61
2aaz E - percentage of sequence identity: 61
2aaz F - percentage of sequence identity: 61
2aaz G - percentage of sequence identity: 61
2aaz H - percentage of sequence identity: 61
2aaz I - percentage of sequence identity: 61
2aaz J - percentage of sequence identity: 61
2aaz K - percentage of sequence identity: 61
2aaz L - percentage of sequence identity: 61
2aaz M - percentage of sequence identity: 61
2aaz N - percentage of sequence identity: 61
2aaz O - percentage of sequence identity: 61
2aaz P - percentage of sequence identity: 61
2tsr A - percentage of sequence identity: 92
2tsr B - percentage of sequence identity: 92
2tsr C - percentage of sequence identity: 92
2tsr D - percentage of sequence identity: 92