PDB: 1hx8 Compound: synapse-enriched clathrin adaptor protein lap Classification: ENDOCYTOSIS/EXOCYTOSIS Entry date in PDB: 2001-02-28 Resolution [Å]: 2.20 R-Factor: 0.211

CHAIN: A SWISS-PROT/TREMBL: Q9VI75    KEYWORD: 3D-structure    Coated pits    Endocytosis    Golgi stack    SCOP: a.7.8.2 All alpha proteins    Spectrin repeat-like    GAT-like domain    Phosphoinositide-binding clathrin adaptor, domain 2    AP180 (Lap)    Fruit fly (Drosophila melanogaster) SCOP: a.118.9.3 All alpha proteins    alpha-alpha superhelix    ENTH/VHS domain    Phosphoinositide-binding clathrin adaptor, N-terminal domain    AP180 (Lap)    Fruit fly (Drosophila melanogaster) GO:  phospholipid binding    CHAIN: B SWISS-PROT/TREMBL: Q9VI75    KEYWORD: 3D-structure    Coated pits    Endocytosis    Golgi stack    SCOP: a.7.8.2 All alpha proteins    Spectrin repeat-like    GAT-like domain    Phosphoinositide-binding clathrin adaptor, domain 2    AP180 (Lap)    Fruit fly (Drosophila melanogaster) SCOP: a.118.9.3 All alpha proteins    alpha-alpha superhelix    ENTH/VHS domain    Phosphoinositide-binding clathrin adaptor, N-terminal domain    AP180 (Lap)    Fruit fly (Drosophila melanogaster) GO:  phospholipid binding

Image Source: PDB

Loops in ArchDB95 clusters

1hx8_A_58 - HH => SUBCLASS : 3.3.1
1hx8_A_41 - HH => SUBCLASS : 5.3.2
1hx8_A_175 - HH => SUBCLASS : 9.17.1

Loops not clustered in ArchDB

1hx8_A_23 - HH
1hx8_A_74 - HH
1hx8_A_93 - HH
1hx8_A_129 - HH
1hx8_A_205 - HH
1hx8_A_242 - HH

1hf8 A - percentage of sequence identity: 66
1hfa A - percentage of sequence identity: 66
1hg2 A - percentage of sequence identity: 66
1hg5 A - percentage of sequence identity: 66
1hx8 A - percentage of sequence identity: 100
1hx8 B - percentage of sequence identity: 100