PDB: 1hxd Compound: bira bifunctional protein Classification: LIGASE Entry date in PDB: 2001-05-30 Resolution [Å]: 2.40 R-Factor: 0.189

CHAIN: A SWISS-PROT/TREMBL: P06709    KEYWORD: 3D-structure    Biotin    Complete proteome    DNA-binding    Ligase    Repressor    Transcription regulation    EC: 6.3.4.15 SCOP: a.4.5.1 All alpha proteins    DNA/RNA-binding 3-helical bundle    "Winged helix" DNA-binding domain    Biotin repressor-like    Biotin repressor, N-terminal domain    Escherichia coli SCOP: b.34.1.1 All beta proteins    SH3-like barrel    C-terminal domain of transcriptional repressors    Biotin repressor (BirA)    Biotin repressor/biotin holoenzyme synthetase, C-terminal domain    Escherichia coli SCOP: d.104.1.2 Alpha and beta proteins (a+b)    Class II aaRS and biotin synthetases    Class II aaRS and biotin synthetases    Biotin holoenzyme synthetase    Biotin repressor/biotin holoenzyme synthetase, catalytic (central) domain    Escherichia coli GO:  biotin-[acetyl-CoA-carboxylase] ligase activity    catalytic activity    transcriptional repressor activity    protein modification    regulation of transcription, DNA-dependent    CHAIN: B SWISS-PROT/TREMBL: P06709    KEYWORD: 3D-structure    Biotin    Complete proteome    DNA-binding    Ligase    Repressor    Transcription regulation    EC: 6.3.4.15 SCOP: a.4.5.1 All alpha proteins    DNA/RNA-binding 3-helical bundle    "Winged helix" DNA-binding domain    Biotin repressor-like    Biotin repressor, N-terminal domain    Escherichia coli SCOP: b.34.1.1 All beta proteins    SH3-like barrel    C-terminal domain of transcriptional repressors    Biotin repressor (BirA)    Biotin repressor/biotin holoenzyme synthetase, C-terminal domain    Escherichia coli SCOP: d.104.1.2 Alpha and beta proteins (a+b)    Class II aaRS and biotin synthetases    Class II aaRS and biotin synthetases    Biotin holoenzyme synthetase    Biotin repressor/biotin holoenzyme synthetase, catalytic (central) domain    Escherichia coli GO:  biotin-[acetyl-CoA-carboxylase] ligase activity    catalytic activity    transcriptional repressor activity    protein modification    regulation of transcription, DNA-dependent

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1bia - - percentage of sequence identity: 100