PDB: 1iau Compound: granzyme b Classification: HYDROLASE Entry date in PDB: 2001-05-02 Resolution [Å]: 2.00 R-Factor: 0.239

CHAIN: A SWISS-PROT/TREMBL: P10144    KEYWORD: 3D-structure    Apoptosis    Cytolysis    Glycoprotein    Hydrolase    Polymorphism    Serine protease    Signal    T-cell    Zymogen    EC: 3.4.21.79 SCOP: b.47.1.2 All beta proteins    Trypsin-like serine proteases    Trypsin-like serine proteases    Eukaryotic proteases    Granzyme B    Human (Homo sapiens) GO:  chymotrypsin activity    trypsin activity    proteolysis and peptidolysis

Image Source: PDB

Loops in ArchDB95 clusters

1iau_A_226 - EH => SUBCLASS : 0.1.2
1iau_A_156 - EH => SUBCLASS : 3.1.3
1iau_A_156 - EH => SUBCLASS : 3.1.4
1iau_A_51 - AR => SUBCLASS : 7.7.1
1iau_A_20 - AR => SUBCLASS : 8.3.1
1iau_A_104 - AR => SUBCLASS : 26.1.1
1iau_A_198 - HA => SUBCLASS : 2.1.2
1iau_A_39 - HA => SUBCLASS : 2.2.45
1iau_A_204 - HA => SUBCLASS : 7.11.1
1iau_A_81 - HA => SUBCLASS : 12.1.1
1iau_A_63 - HA => SUBCLASS : 12.2.1
1iau_A_135 - HA => SUBCLASS : 14.4.1

Loops in ArchDB-EC clusters

1iau_A_63 - HA => SUBCLASS : 12.2.1

Loops not clustered in ArchDB

1iau_A_180 - AR
1iau_A_20 - AR
1iau_A_180 - AR
1iau_A_51 - AR
1iau_A_104 - AR
1iau_A_204 - HA
1iau_A_198 - HA
1iau_A_135 - HA
1iau_A_81 - HA
1iau_A_63 - HA
1iau_A_39 - HA
1iau_A_30 - HA
1iau_A_30 - HA
1iau_A_165 - HE

1fi8 B - percentage of sequence identity: 70
1fq3 A - percentage of sequence identity: 99
1fq3 B - percentage of sequence identity: 99