PDB: 1iv3 Compound: 2-c-methyl-d-erythritol 2,4-cyclodiphosphate synth Classification: LYASE Entry date in PDB: 2002-09-11 Resolution [Å]: 1.52 R-Factor: 0.203

CHAIN: A SWISS-PROT/TREMBL: Q8RQP5    KEYWORD: Lyase    EC: 4.6.1.12 SCOP: d.79.5.1 Alpha and beta proteins (a+b)    Bacillus chorismate mutase-like    2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase IspF    2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase IspF    2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase IspF    Thermus thermophilus GO:  2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity    terpenoid biosynthesis    CHAIN: B SWISS-PROT/TREMBL: Q8RQP5    KEYWORD: Lyase    EC: 4.6.1.12 SCOP: d.79.5.1 Alpha and beta proteins (a+b)    Bacillus chorismate mutase-like    2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase IspF    2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase IspF    2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase IspF    Thermus thermophilus GO:  2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity    terpenoid biosynthesis    CHAIN: C SWISS-PROT/TREMBL: Q8RQP5    KEYWORD: Lyase    EC: 4.6.1.12 SCOP: d.79.5.1 Alpha and beta proteins (a+b)    Bacillus chorismate mutase-like    2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase IspF    2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase IspF    2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase IspF    Thermus thermophilus GO:  2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity    terpenoid biosynthesis    CHAIN: D SWISS-PROT/TREMBL: Q8RQP5    KEYWORD: Lyase    EC: 4.6.1.12 SCOP: d.79.5.1 Alpha and beta proteins (a+b)    Bacillus chorismate mutase-like    2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase IspF    2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase IspF    2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase IspF    Thermus thermophilus GO:  2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity    terpenoid biosynthesis    CHAIN: E SWISS-PROT/TREMBL: Q8RQP5    KEYWORD: Lyase    EC: 4.6.1.12 SCOP: d.79.5.1 Alpha and beta proteins (a+b)    Bacillus chorismate mutase-like    2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase IspF    2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase IspF    2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase IspF    Thermus thermophilus GO:  2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity    terpenoid biosynthesis    CHAIN: F SWISS-PROT/TREMBL: Q8RQP5    KEYWORD: Lyase    EC: 4.6.1.12 SCOP: d.79.5.1 Alpha and beta proteins (a+b)    Bacillus chorismate mutase-like    2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase IspF    2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase IspF    2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase IspF    Thermus thermophilus GO:  2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity    terpenoid biosynthesis

Image Source: PDB

Loops in ArchDB40 clusters

1iv3_A_73 - HE => SUBCLASS : 2.2.4
1iv3_A_109 - HE => SUBCLASS : 6.1.1
1iv3_A_18 - HA => SUBCLASS : 2.1.1
1iv3_A_23 - AR => SUBCLASS : 3.10.2

Loops in ArchDB95 clusters

1iv3_A_23 - AR => SUBCLASS : 3.13.2
1iv3_A_73 - HE => SUBCLASS : 2.1.23
1iv3_A_109 - HE => SUBCLASS : 6.1.1
1iv3_A_18 - HA => SUBCLASS : 2.1.1

Loops in ArchDB-EC clusters

1iv3_A_109 - HE => SUBCLASS : 6.2.1

Loops not clustered in ArchDB

1iv3_A_127 - AR
1iv3_A_23 - AR
1iv3_A_3 - AR
1iv3_A_127 - AR
1iv3_A_3 - AR
1iv3_A_91 - EH
1iv3_A_29 - EH
1iv3_A_18 - HA
1iv3_A_57 - HH
1iv3_A_39 - HH

1iv1 A - percentage of sequence identity: 98
1iv1 B - percentage of sequence identity: 98
1iv1 C - percentage of sequence identity: 98
1iv1 D - percentage of sequence identity: 98
1iv1 E - percentage of sequence identity: 98
1iv1 F - percentage of sequence identity: 98
1iv2 A - percentage of sequence identity: 100
1iv2 B - percentage of sequence identity: 100
1iv2 C - percentage of sequence identity: 100
1iv2 D - percentage of sequence identity: 100
1iv2 E - percentage of sequence identity: 100
1iv2 F - percentage of sequence identity: 100
1iv3 A - percentage of sequence identity: 100
1iv3 B - percentage of sequence identity: 100
1iv3 C - percentage of sequence identity: 100
1iv3 D - percentage of sequence identity: 100
1iv3 E - percentage of sequence identity: 100
1iv3 F - percentage of sequence identity: 100
1iv4 A - percentage of sequence identity: 100
1iv4 B - percentage of sequence identity: 100
1iv4 C - percentage of sequence identity: 100
1iv4 D - percentage of sequence identity: 100
1iv4 E - percentage of sequence identity: 100
1iv4 F - percentage of sequence identity: 100