Home
Classification
Query
Statistics
Contact
Links
Help
PDB code:
Information on 1j3i
PDB:
1j3i
Compound:
bifunctional dihydrofolate reductase-thymidylate s
Classification:
OXIDOREDUCTASE, TRANSFERASE
Entry date in PDB:
2003-05-06
Resolution [Å]:
2.33
R-Factor:
0.185
CHAIN:
A
SWISS-PROT/TREMBL:
P13922
KEYWORD:
3D-structure Methyltransferase Multifunctional enzyme NADP Nucleotide biosynthesis One-carbon metabolism Oxidoreductase Transferase
EC:
1.5.1.3
SCOP:
c.71.1.1
Alpha and beta proteins (a/b)
Dihydrofolate reductases
Dihydrofolate reductases
Dihydrofolate reductases
Bifunctional enzyme dihydrofolate reductase-thymidylate synthase, DFR domain
Malaria parasite (Plasmodium falciparum)
GO:
dihydrofolate reductase activity
thymidylate synthase activity
dTMP biosynthesis
glycine biosynthesis
nucleotide biosynthesis
CHAIN:
B
SWISS-PROT/TREMBL:
P13922
KEYWORD:
3D-structure Methyltransferase Multifunctional enzyme NADP Nucleotide biosynthesis One-carbon metabolism Oxidoreductase Transferase
EC:
1.5.1.3
SCOP:
c.71.1.1
Alpha and beta proteins (a/b)
Dihydrofolate reductases
Dihydrofolate reductases
Dihydrofolate reductases
Bifunctional enzyme dihydrofolate reductase-thymidylate synthase, DFR domain
Malaria parasite (Plasmodium falciparum)
GO:
dihydrofolate reductase activity
thymidylate synthase activity
dTMP biosynthesis
glycine biosynthesis
nucleotide biosynthesis
CHAIN:
C
SWISS-PROT/TREMBL:
P13922
KEYWORD:
3D-structure Methyltransferase Multifunctional enzyme NADP Nucleotide biosynthesis One-carbon metabolism Oxidoreductase Transferase
EC:
1.5.1.3
SCOP:
d.117.1.1
Alpha and beta proteins (a+b)
Thymidylate synthase/dCMP hydroxymethylase
Thymidylate synthase/dCMP hydroxymethylase
Thymidylate synthase/dCMP hydroxymethylase
Bifunctional enzyme dihydrofolate reductase-thymidylate synthase, TS domain
Malaria parasite (Plasmodium falciparum)
GO:
dihydrofolate reductase activity
thymidylate synthase activity
dTMP biosynthesis
glycine biosynthesis
nucleotide biosynthesis
CHAIN:
D
SWISS-PROT/TREMBL:
P13922
KEYWORD:
3D-structure Methyltransferase Multifunctional enzyme NADP Nucleotide biosynthesis One-carbon metabolism Oxidoreductase Transferase
EC:
1.5.1.3
SCOP:
d.117.1.1
Alpha and beta proteins (a+b)
Thymidylate synthase/dCMP hydroxymethylase
Thymidylate synthase/dCMP hydroxymethylase
Thymidylate synthase/dCMP hydroxymethylase
Bifunctional enzyme dihydrofolate reductase-thymidylate synthase, TS domain
Malaria parasite (Plasmodium falciparum)
GO:
dihydrofolate reductase activity
thymidylate synthase activity
dTMP biosynthesis
glycine biosynthesis
nucleotide biosynthesis
Image Source:
PDB
Homologous structures to 1j3i classified in ArchDB
1j3k
C - percentage of sequence identity: 100