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Information on 1j3j
PDB: 1j3j
Compound: bifunctional dihydrofolate reductase-thymidylate s
Classification: OXIDOREDUCTASE, TRANSFERASE
Entry date in PDB: 2003-05-06
Resolution [Å]: 2.30
R-Factor: 0.198


CHAIN: A
SWISS-PROT/TREMBL: P13922
   KEYWORD: 3D-structure    Methyltransferase    Multifunctional enzyme    NADP    Nucleotide biosynthesis    One-carbon metabolism    Oxidoreductase    Transferase   
EC: 1.5.1.3
SCOP: c.71.1.1 Alpha and beta proteins (a/b)    Dihydrofolate reductases    Dihydrofolate reductases    Dihydrofolate reductases    Bifunctional enzyme dihydrofolate reductase-thymidylate synthase, DFR domain    Malaria parasite (Plasmodium falciparum)
GO:  dihydrofolate reductase activity    thymidylate synthase activity    dTMP biosynthesis    glycine biosynthesis    nucleotide biosynthesis   


CHAIN: B
SWISS-PROT/TREMBL: P13922
   KEYWORD: 3D-structure    Methyltransferase    Multifunctional enzyme    NADP    Nucleotide biosynthesis    One-carbon metabolism    Oxidoreductase    Transferase   
EC: 1.5.1.3
SCOP: c.71.1.1 Alpha and beta proteins (a/b)    Dihydrofolate reductases    Dihydrofolate reductases    Dihydrofolate reductases    Bifunctional enzyme dihydrofolate reductase-thymidylate synthase, DFR domain    Malaria parasite (Plasmodium falciparum)
GO:  dihydrofolate reductase activity    thymidylate synthase activity    dTMP biosynthesis    glycine biosynthesis    nucleotide biosynthesis   


CHAIN: C
SWISS-PROT/TREMBL: P13922
   KEYWORD: 3D-structure    Methyltransferase    Multifunctional enzyme    NADP    Nucleotide biosynthesis    One-carbon metabolism    Oxidoreductase    Transferase   
EC: 1.5.1.3
SCOP: d.117.1.1 Alpha and beta proteins (a+b)    Thymidylate synthase/dCMP hydroxymethylase    Thymidylate synthase/dCMP hydroxymethylase    Thymidylate synthase/dCMP hydroxymethylase    Bifunctional enzyme dihydrofolate reductase-thymidylate synthase, TS domain    Cryptosporidium hominis
GO:  dihydrofolate reductase activity    thymidylate synthase activity    dTMP biosynthesis    glycine biosynthesis    nucleotide biosynthesis   


CHAIN: D
SWISS-PROT/TREMBL: P13922
   KEYWORD: 3D-structure    Methyltransferase    Multifunctional enzyme    NADP    Nucleotide biosynthesis    One-carbon metabolism    Oxidoreductase    Transferase   
EC: 1.5.1.3
SCOP: d.117.1.1 Alpha and beta proteins (a+b)    Thymidylate synthase/dCMP hydroxymethylase    Thymidylate synthase/dCMP hydroxymethylase    Thymidylate synthase/dCMP hydroxymethylase    Bifunctional enzyme dihydrofolate reductase-thymidylate synthase, TS domain    Cryptosporidium hominis
GO:  dihydrofolate reductase activity    thymidylate synthase activity    dTMP biosynthesis    glycine biosynthesis    nucleotide biosynthesis   
1j3j Image
Image Source: PDB
Homologous structures to 1j3j classified in ArchDB

1j3k C - percentage of sequence identity: 100