PDB: 1k2p Compound: tyrosine-protein kinase btk Classification: TRANSFERASE Entry date in PDB: 2002-06-26 Resolution [Å]: 2.10 R-Factor: 0.221

CHAIN: A SWISS-PROT/TREMBL: Q06187    KEYWORD: 3D-structure    ATP-binding    Disease mutation    Metal-binding    Phosphorylation    Polymorphism    SH2 domain    SH3 domain    Transferase    Tyrosine-protein kinase    Zinc    EC: 2.7.1.112 SCOP: d.144.1.7 Alpha and beta proteins (a+b)    Protein kinase-like (PK-like)    Protein kinase-like (PK-like)    Protein kinases, catalytic subunit    Bruton's tyrosine kinase (Btk)    Human (Homo sapiens) GO:  ATP binding    protein kinase activity    protein-tyrosine kinase activity    intracellular signaling cascade    protein amino acid phosphorylation    CHAIN: B SWISS-PROT/TREMBL: Q06187    KEYWORD: 3D-structure    ATP-binding    Disease mutation    Metal-binding    Phosphorylation    Polymorphism    SH2 domain    SH3 domain    Transferase    Tyrosine-protein kinase    Zinc    EC: 2.7.1.112 SCOP: d.144.1.7 Alpha and beta proteins (a+b)    Protein kinase-like (PK-like)    Protein kinase-like (PK-like)    Protein kinases, catalytic subunit    Bruton's tyrosine kinase (Btk)    Human (Homo sapiens) GO:  ATP binding    protein kinase activity    protein-tyrosine kinase activity    intracellular signaling cascade    protein amino acid phosphorylation

Image Source: PDB

Loops in ArchDB40 clusters

1k2p_A_439 - HE => SUBCLASS : 8.1.1
1k2p_A_410 - HA => SUBCLASS : 2.2.10
1k2p_A_527 - HA => SUBCLASS : 3.1.1
1k2p_A_470 - AR => SUBCLASS : 4.19.1
1k2p_A_566 - HH => SUBCLASS : 4.7.1

Loops in ArchDB95 clusters

1k2p_A_470 - AR => SUBCLASS : 4.12.1
1k2p_A_566 - HH => SUBCLASS : 4.3.1
1k2p_A_576 - HH => SUBCLASS : 10.8.1
1k2p_A_603 - HH => SUBCLASS : 11.4.1
1k2p_A_439 - HE => SUBCLASS : 8.2.1
1k2p_A_527 - HA => SUBCLASS : 3.1.1

Loops in ArchDB-EC clusters

1k2p_A_603 - HH => SUBCLASS : 11.4.1

Loops not clustered in ArchDB

1k2p_A_470 - AR
1k2p_A_425 - EH
1k2p_A_480 - EH
1k2p_A_535 - EH
1k2p_A_460 - HA
1k2p_A_414 - HA
1k2p_A_410 - HA
1k2p_A_460 - HA
1k2p_A_414 - HA
1k2p_A_527 - HA
1k2p_A_495 - HE
1k2p_A_624 - HH
1k2p_A_482 - HH

1k2p A - percentage of sequence identity: 100
1k2p B - percentage of sequence identity: 100