PDB: 1k3a Compound: insulin-like growth factor 1 receptor Classification: TRANSFERASE Entry date in PDB: 2001-11-28 Resolution [Å]: 2.10 R-Factor: 0.212

CHAIN: A SWISS-PROT/TREMBL: P08069    KEYWORD: 3D-structure    ATP-binding    Glycoprotein    Phosphorylation    Receptor    Repeat    Signal    Transferase    Transmembrane    Tyrosine-protein kinase    EC: 2.7.1.112 SCOP: d.144.1.7 Alpha and beta proteins (a+b)    Protein kinase-like (PK-like)    Protein kinase-like (PK-like)    Protein kinases, catalytic subunit    Insulin-like growth factor 1 receptor    Human (Homo sapiens) GO:  membrane    ATP binding    epidermal growth factor receptor activity    protein kinase activity    protein-tyrosine kinase activity    transmembrane receptor protein tyrosine kinase activity    protein amino acid phosphorylation    transmembrane receptor protein tyrosine kinase signaling pathway    CHAIN: B SWISS-PROT/TREMBL: P35568    KEYWORD: 3D-structure    Diabetes mellitus    Disease mutation    Phosphorylation    Polymorphism    GO:

Image Source: PDB

Loops in ArchDB-KI clusters

1k3a_A_1119 - AR => SUBCLASS : 5.1.1
1k3a_A_1101 - AR => SUBCLASS : 8.1.1
1k3a_A_1045 - EH => SUBCLASS : 6.3.2
1k3a_A_1111 - HA => SUBCLASS : 4.2.1
1k3a_A_1079 - HE => SUBCLASS : 1.1.4
1k3a_A_1079 - HE => SUBCLASS : 1.1.5
1k3a_A_1011 - HE => SUBCLASS : 8.2.1
1k3a_A_1151 - HH => SUBCLASS : 4.3.1
1k3a_A_1209 - HH => SUBCLASS : 9.1.2
1k3a_A_1188 - HH => SUBCLASS : 11.1.2

Loops not clustered in ArchDB-KI

1k3a_A_1128 - EH
1k3a_A_995 - EH
1k3a_A_982 - HA
1k3a_A_1035 - HA
1k3a_A_1229 - HH
1k3a_A_1057 - HH
1k3a_A_1161 - HH

1ir3 A - percentage of sequence identity: 80
1p4o A - percentage of sequence identity: 98