PDB: 1k78 Compound: paired box protein pax5 Classification: TRANSCRIPTION/DNA Entry date in PDB: 2002-01-04 Resolution [Å]: 2.25 R-Factor: 0.227

CHAIN: A SWISS-PROT/TREMBL: Q02548    KEYWORD: 3D-structure    Developmental protein    Differentiation    DNA-binding    Glycoprotein    Neurogenesis    Nuclear protein    Paired box    Spermatogenesis    Transcription regulation    SCOP: a.4.1.5 All alpha proteins    DNA/RNA-binding 3-helical bundle    Homeodomain-like    Paired domain    Pax-5    Human (Homo sapiens) SCOP: a.4.1.5 All alpha proteins    DNA/RNA-binding 3-helical bundle    Homeodomain-like    Paired domain    Pax-5    Human (Homo sapiens) GO:  nucleus    development    CHAIN: B SWISS-PROT/TREMBL: P27577    KEYWORD: 3D-structure    Alternative splicing    DNA-binding    Nuclear protein    Phosphorylation    Proto-oncogene    Transcription regulation    SCOP: a.4.5.21 All alpha proteins    DNA/RNA-binding 3-helical bundle    "Winged helix" DNA-binding domain    ets domain    ETS-1 transcription factor, residues 331-440    Mouse (Mus musculus) GO:  nucleus    DNA binding    transcription factor activity    regulation of transcription, DNA-dependent    CHAIN: E SWISS-PROT/TREMBL: Q02548    KEYWORD: 3D-structure    Developmental protein    Differentiation    DNA-binding    Glycoprotein    Neurogenesis    Nuclear protein    Paired box    Spermatogenesis    Transcription regulation    SCOP: a.4.1.5 All alpha proteins    DNA/RNA-binding 3-helical bundle    Homeodomain-like    Paired domain    Pax-5    Human (Homo sapiens) SCOP: a.4.1.5 All alpha proteins    DNA/RNA-binding 3-helical bundle    Homeodomain-like    Paired domain    Pax-5    Human (Homo sapiens) GO:  nucleus    development    CHAIN: F SWISS-PROT/TREMBL: P27577    KEYWORD: 3D-structure    Alternative splicing    DNA-binding    Nuclear protein    Phosphorylation    Proto-oncogene    Transcription regulation    SCOP: a.4.5.21 All alpha proteins    DNA/RNA-binding 3-helical bundle    "Winged helix" DNA-binding domain    ets domain    ETS-1 transcription factor, residues 331-440    Mouse (Mus musculus) GO:  nucleus    DNA binding    transcription factor activity    regulation of transcription, DNA-dependent    CHAIN: I SWISS-PROT/TREMBL: Q02548    KEYWORD: 3D-structure    Developmental protein    Differentiation    DNA-binding    Glycoprotein    Neurogenesis    Nuclear protein    Paired box    Spermatogenesis    Transcription regulation    SCOP: a.4.1.5 All alpha proteins    DNA/RNA-binding 3-helical bundle    Homeodomain-like    Paired domain    Pax-5    Human (Homo sapiens) GO:  nucleus    development

Image Source: PDB

Loops in ArchDB95 clusters

1k78_A_93 - HH => SUBCLASS : 5.2.1
1k78_A_111 - HH => SUBCLASS : 10.18.1

Loops not clustered in ArchDB

1k78_A_35 - HH
1k78_A_51 - HH
1k78_A_62 - HH

1bc8 C - percentage of sequence identity: 60
1dux C - percentage of sequence identity: 63
1gvj A - percentage of sequence identity: 100
1k78 A - percentage of sequence identity: 100
1k78 E - percentage of sequence identity: 100
1k78 I - percentage of sequence identity: 100
1k79 A - percentage of sequence identity: 100
1mdm A - percentage of sequence identity: 100
1pdn C - percentage of sequence identity: 66
6pax A - percentage of sequence identity: 77