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Information on 1ktz
PDB: 1ktz
Compound: transforming growth factor beta 3
Classification: CYTOKINE/CYTOKINE RECEPTOR
Entry date in PDB: 2002-02-27
Resolution [Å]: 2.15
R-Factor: 0.201


CHAIN: A
SWISS-PROT/TREMBL: P10600
   KEYWORD: 3D-structure    Glycoprotein    Growth factor    Mitogen    Polymorphism    Signal   
SCOP: g.17.1.2 Small proteins    Cystine-knot cytokines    Cystine-knot cytokines    Transforming growth factor (TGF)-beta    TGF-beta3    Human (Homo sapiens)
GO:  growth factor activity    transforming growth factor beta receptor binding    cell growth    growth   


CHAIN: B
SWISS-PROT/TREMBL: P37173
   KEYWORD: 3D-structure    ATP-binding    Disease mutation    Glycoprotein    Hereditary nonpolyposis colorectal cancer    Phosphorylation    Polymorphism    Receptor    Serine/threonine-protein kinase    Signal    Transferase    Transmembrane   
EC: 2.7.1.37
SCOP: g.7.1.3 Small proteins    Snake toxin-like    Snake toxin-like    Extracellular domain of cell surface receptors    TGF-beta type II receptor extracellular domain    Human (Homo sapiens)
GO:  membrane    ATP binding    protein kinase activity    protein serine/threonine kinase activity    receptor signaling protein serine/threonine kinase activity    transforming growth factor beta receptor activity    transmembrane receptor protein serine/threonine kinase activity    protein amino acid phosphorylation    transmembrane receptor protein serine/threonine kinase signaling pathway   
1ktz Image
Image Source: PDB

Stored Loops of 1ktz

Loops in ArchDB95 clusters

1ktz_A_78 - AR => SUBCLASS : 2.4.2
1ktz_A_24 - HE => SUBCLASS : 4.7.4
1ktz_A_24 - HE => SUBCLASS : 4.38.1

Loops not clustered in ArchDB

1ktz_A_16 - AR
1ktz_A_33 - AR
1ktz_A_38 - AR
1ktz_A_43 - AR
1ktz_A_95 - AR
1ktz_A_21 - EH
1ktz_A_83 - HA

Homologous structures to 1ktz classified in ArchDB

1kla A - percentage of sequence identity: 76
1kla B - percentage of sequence identity: 76
1klc A - percentage of sequence identity: 76
1klc B - percentage of sequence identity: 76
1kld A - percentage of sequence identity: 76
1kld B - percentage of sequence identity: 76
1m9z A - percentage of sequence identity: 99
1tfg - - percentage of sequence identity: 79
1tgk - - percentage of sequence identity: 100