PDB: 1l8a Compound: pyruvate dehydrogenase e1 component Classification: OXIDOREDUCTASE Entry date in PDB: 2002-07-24 Resolution [Å]: 1.85 R-Factor: 0.189

CHAIN: A SWISS-PROT/TREMBL: P06958    KEYWORD: 3D-structure    Complete proteome    Flavoprotein    Glycolysis    Magnesium    Oxidoreductase    Thiamine pyrophosphate    EC: 1.2.4.1 SCOP: c.36.1.6 Alpha and beta proteins (a/b)    Thiamin diphosphate-binding fold (THDP-binding)    Thiamin diphosphate-binding fold (THDP-binding)    TK-like Pyr module    Pyruvate dehydrogenase E1 component, Pyr module    Escherichia coli SCOP: c.36.1.10 Alpha and beta proteins (a/b)    Thiamin diphosphate-binding fold (THDP-binding)    Thiamin diphosphate-binding fold (THDP-binding)    TK-like PP module    Pyruvate dehydrogenase E1 component, PP module    Escherichia coli SCOP: c.48.1.1 Alpha and beta proteins (a/b)    TK C-terminal domain-like    TK C-terminal domain-like    Transketolase C-terminal domain-like    Pyruvate dehydrogenase E1 component, C-domain    Escherichia coli GO:  oxidoreductase activity    oxidoreductase activity    CHAIN: B SWISS-PROT/TREMBL: P06958    KEYWORD: 3D-structure    Complete proteome    Flavoprotein    Glycolysis    Magnesium    Oxidoreductase    Thiamine pyrophosphate    EC: 1.2.4.1 SCOP: c.36.1.6 Alpha and beta proteins (a/b)    Thiamin diphosphate-binding fold (THDP-binding)    Thiamin diphosphate-binding fold (THDP-binding)    TK-like Pyr module    Pyruvate dehydrogenase E1 component, Pyr module    Escherichia coli SCOP: c.36.1.10 Alpha and beta proteins (a/b)    Thiamin diphosphate-binding fold (THDP-binding)    Thiamin diphosphate-binding fold (THDP-binding)    TK-like PP module    Pyruvate dehydrogenase E1 component, PP module    Escherichia coli SCOP: c.48.1.1 Alpha and beta proteins (a/b)    TK C-terminal domain-like    TK C-terminal domain-like    Transketolase C-terminal domain-like    Pyruvate dehydrogenase E1 component, C-domain    Escherichia coli GO:  oxidoreductase activity    oxidoreductase activity

Image Source: PDB

Loops in ArchDB40 clusters

1l8a_A_262 - HA => SUBCLASS : 2.2.2
1l8a_A_136 - EH => SUBCLASS : 1.1.16
1l8a_A_724 - EH => SUBCLASS : 1.2.5
1l8a_A_724 - EH => SUBCLASS : 1.2.6
1l8a_A_751 - EH => SUBCLASS : 3.7.1
1l8a_A_224 - EH => SUBCLASS : 6.3.2
1l8a_A_253 - AR => SUBCLASS : 1.2.4
1l8a_A_309 - HH => SUBCLASS : 2.1.1
1l8a_A_144 - HH => SUBCLASS : 4.1.1
1l8a_A_845 - HH => SUBCLASS : 4.1.3
1l8a_A_144 - HH => SUBCLASS : 4.1.5
1l8a_A_298 - HH => SUBCLASS : 4.33.1

Loops in ArchDB95 clusters

1l8a_A_724 - EH => SUBCLASS : 1.3.5
1l8a_A_655 - EH => SUBCLASS : 2.1.9
1l8a_A_751 - EH => SUBCLASS : 3.3.3
1l8a_A_565 - EH => SUBCLASS : 4.76.1
1l8a_A_224 - EH => SUBCLASS : 6.3.2
1l8a_A_253 - AR => SUBCLASS : 2.8.1
1l8a_A_309 - HH => SUBCLASS : 2.1.1
1l8a_A_144 - HH => SUBCLASS : 4.1.1
1l8a_A_845 - HH => SUBCLASS : 4.1.2
1l8a_A_298 - HH => SUBCLASS : 4.44.1
1l8a_A_274 - HE => SUBCLASS : 1.1.1
1l8a_A_735 - HE => SUBCLASS : 1.1.6
1l8a_A_706 - HE => SUBCLASS : 2.1.3
1l8a_A_645 - HE => SUBCLASS : 3.4.1
1l8a_A_604 - HE => SUBCLASS : 3.5.1
1l8a_A_645 - HE => SUBCLASS : 3.6.2
1l8a_A_242 - HE => SUBCLASS : 4.7.1
1l8a_A_366 - HE => SUBCLASS : 4.20.1
1l8a_A_366 - HE => SUBCLASS : 5.51.1
1l8a_A_262 - HA => SUBCLASS : 2.2.2

Loops in ArchDB-EC clusters

1l8a_A_845 - HH => SUBCLASS : 4.1.4

Loops not clustered in ArchDB

1l8a_A_714 - AR
1l8a_A_253 - AR
1l8a_A_714 - AR
1l8a_A_266 - EH
1l8a_A_820 - EH
1l8a_A_797 - EH
1l8a_A_686 - EH
1l8a_A_622 - EH
1l8a_A_593 - EH
1l8a_A_384 - EH
1l8a_A_288 - EH
1l8a_A_515 - EH
1l8a_A_262 - HA
1l8a_A_806 - HE
1l8a_A_787 - HE
1l8a_A_663 - HE
1l8a_A_108 - HE
1l8a_A_196 - HE
1l8a_A_494 - HE
1l8a_A_529 - HE
1l8a_A_584 - HE
1l8a_A_834 - HH
1l8a_A_761 - HH
1l8a_A_571 - HH
1l8a_A_482 - HH
1l8a_A_446 - HH
1l8a_A_415 - HH
1l8a_A_353 - HH
1l8a_A_342 - HH
1l8a_A_330 - HH
1l8a_A_319 - HH
1l8a_A_236 - HH
1l8a_A_159 - HH
1l8a_A_75 - HH

1l8a A - percentage of sequence identity: 100
1l8a B - percentage of sequence identity: 100
1rp7 A - percentage of sequence identity: 100
1rp7 B - percentage of sequence identity: 100