PDB: 1lck Compound: p56==lck== tyrosine kinase Classification: COMPLEX (KINASE/PEPTIDE) Entry date in PDB: 1995-10-15 Resolution [Å]: 2.50 R-Factor: 0.190

CHAIN: A SWISS-PROT/TREMBL: P06239    KEYWORD: 3D-structure    Alternative splicing    ATP-binding    Chromosomal translocation    Disease mutation    Lipoprotein    Myristate    Palmitate    Phosphorylation    Proto-oncogene    SH2 domain    SH3 domain    Transferase    Tyrosine-protein kinase    EC: 2.7.1.112 SCOP: b.34.2.1 All beta proteins    SH3-like barrel    SH3-domain    SH3-domain    p56-lck tyrosine kinase, SH3 domain    Human (Homo sapiens) SCOP: d.93.1.1 Alpha and beta proteins (a+b)    SH2-like    SH2 domain    SH2 domain    p56-lck tyrosine kinase    Human (Homo sapiens) GO:  ATP binding    protein kinase activity    protein-tyrosine kinase activity    intracellular signaling cascade    protein amino acid phosphorylation    CHAIN: B SWISS-PROT/TREMBL: P06239    KEYWORD: 3D-structure    Alternative splicing    ATP-binding    Chromosomal translocation    Disease mutation    Lipoprotein    Myristate    Palmitate    Phosphorylation    Proto-oncogene    SH2 domain    SH3 domain    Transferase    Tyrosine-protein kinase    EC: 2.7.1.112 GO:

Image Source: PDB

Loops in ArchDB95 clusters

1lck_A_108 - AR => SUBCLASS : 3.2.4
1lck_A_97 - HA => SUBCLASS : 4.1.2
1lck_A_191 - HA => SUBCLASS : 4.2.1

Loops not clustered in ArchDB

1lck_A_116 - EH
1lck_A_198 - EH
1lck_A_65 - HA
1lck_A_87 - HA
1lck_A_150 - HA
1lck_A_163 - HA
1lck_A_178 - HA
1lck_A_134 - HE
1lck_A_202 - HE

1ad5 A - percentage of sequence identity: 64
1ad5 B - percentage of sequence identity: 64
1bhf A - percentage of sequence identity: 100
1bhh A - percentage of sequence identity: 100
1bhh B - percentage of sequence identity: 100
1blj - - percentage of sequence identity: 68
1blk - - percentage of sequence identity: 68
1cwe A - percentage of sequence identity: 100
1cwe C - percentage of sequence identity: 100
1fbz A - percentage of sequence identity: 99
1fbz B - percentage of sequence identity: 99
1h92 A - percentage of sequence identity: 98
1ijr A - percentage of sequence identity: 99
1kik A - percentage of sequence identity: 100
1lcj A - percentage of sequence identity: 100
1lkl A - percentage of sequence identity: 100
1x27 A - percentage of sequence identity: 100
1x27 B - percentage of sequence identity: 100
1x27 C - percentage of sequence identity: 100
1x27 D - percentage of sequence identity: 100
1x27 E - percentage of sequence identity: 100
1x27 F - percentage of sequence identity: 100
2hck A - percentage of sequence identity: 64
2hck B - percentage of sequence identity: 64
3hck - - percentage of sequence identity: 69