PDB: 1lw3 Compound: myotubularin-related protein 2 Classification: HYDROLASE Entry date in PDB: 2003-10-07 Resolution [Å]: 2.30 R-Factor: 0.209

CHAIN: A SWISS-PROT/TREMBL: Q13614    KEYWORD: Charcot-Marie-Tooth disease    Hydrolase    EC: 3.1.3.- SCOP: b.55.1.8 All beta proteins    PH domain-like    PH domain-like    GRAM domain    Myotubularin-related protein 2, N-terminal domain    Human (Homo sapiens) SCOP: c.45.1.3 Alpha and beta proteins (a/b)    (Phosphotyrosine protein) phosphatases II    (Phosphotyrosine protein) phosphatases II    Myotubularin-like phosphatases    Myotubularin-related protein 2, C-terminal domain    Human (Homo sapiens) GO:  inositol or phosphatidylinositol phosphatase activity    phosphoprotein phosphatase activity    phospholipid dephosphorylation    protein amino acid dephosphorylation

Image Source: PDB

Loops in ArchDB40 clusters

1lw3_A_99 - HA => SUBCLASS : 2.2.22
1lw3_A_150 - HA => SUBCLASS : 3.1.1
1lw3_A_84 - HA => SUBCLASS : 3.2.3
1lw3_A_269 - HA => SUBCLASS : 6.1.3
1lw3_A_316 - EH => SUBCLASS : 3.6.3
1lw3_A_244 - EH => SUBCLASS : 5.11.1
1lw3_A_159 - EH => SUBCLASS : 5.34.1
1lw3_A_123 - AR => SUBCLASS : 3.4.1
1lw3_A_379 - HH => SUBCLASS : 1.3.1
1lw3_A_525 - HH => SUBCLASS : 1.3.8
1lw3_A_423 - HH => SUBCLASS : 6.17.1

Loops in ArchDB95 clusters

1lw3_A_316 - EH => SUBCLASS : 3.4.3
1lw3_A_159 - EH => SUBCLASS : 4.20.1
1lw3_A_244 - EH => SUBCLASS : 5.3.2
1lw3_A_159 - EH => SUBCLASS : 5.42.1
1lw3_A_123 - AR => SUBCLASS : 3.2.2
1lw3_A_379 - HH => SUBCLASS : 1.3.1
1lw3_A_525 - HH => SUBCLASS : 1.3.5
1lw3_A_525 - HH => SUBCLASS : 1.3.6
1lw3_A_423 - HH => SUBCLASS : 6.40.1
1lw3_A_99 - HA => SUBCLASS : 2.2.1
1lw3_A_150 - HA => SUBCLASS : 3.1.1
1lw3_A_84 - HA => SUBCLASS : 3.3.4
1lw3_A_269 - HA => SUBCLASS : 4.1.6
1lw3_A_111 - HA => SUBCLASS : 6.1.1

Loops in ArchDB-EC clusters

1lw3_A_525 - HH => SUBCLASS : 1.3.4

Loops not clustered in ArchDB

1lw3_A_123 - AR
1lw3_A_280 - EH
1lw3_A_413 - EH
1lw3_A_346 - EH
1lw3_A_225 - HA
1lw3_A_132 - HA
1lw3_A_225 - HA
1lw3_A_84 - HA
1lw3_A_99 - HA
1lw3_A_111 - HA
1lw3_A_132 - HA
1lw3_A_150 - HA
1lw3_A_269 - HA
1lw3_A_211 - HE
1lw3_A_252 - HE
1lw3_A_297 - HE
1lw3_A_324 - HE
1lw3_A_388 - HE
1lw3_A_479 - HH
1lw3_A_172 - HH
1lw3_A_356 - HH
1lw3_A_442 - HH
1lw3_A_460 - HH
1lw3_A_540 - HH
1lw3_A_533 - HH
1lw3_A_502 - HH

1m7r A - percentage of sequence identity: 100
1m7r B - percentage of sequence identity: 100
1zsq A - percentage of sequence identity: 97
1zvr A - percentage of sequence identity: 97