PDB: 1lwd Compound: isocitrate dehydrogenase Classification: OXIDOREDUCTASE Entry date in PDB: 2002-11-13 Resolution [Å]: 1.85 R-Factor: 0.182

CHAIN: A SWISS-PROT/TREMBL: P33198    KEYWORD: 3D-structure    Glyoxylate bypass    Mitochondrion    NADP    Oxidoreductase    Transit peptide    Tricarboxylic acid cycle    EC: 1.1.1.42 SCOP: c.77.1.1 Alpha and beta proteins (a/b)    Isocitrate/Isopropylmalate dehydrogenase-like    Isocitrate/Isopropylmalate dehydrogenase-like    Dimeric isocitrate & isopropylmalate dehydrogenases    NADP-dependent isocitrate dehydrogenase    Pig (Sus scrofa) GO:  isocitrate dehydrogenase (NADP+) activity    oxidoreductase activity    main pathways of carbohydrate metabolism    metabolism    CHAIN: B SWISS-PROT/TREMBL: P33198    KEYWORD: 3D-structure    Glyoxylate bypass    Mitochondrion    NADP    Oxidoreductase    Transit peptide    Tricarboxylic acid cycle    EC: 1.1.1.42 SCOP: c.77.1.1 Alpha and beta proteins (a/b)    Isocitrate/Isopropylmalate dehydrogenase-like    Isocitrate/Isopropylmalate dehydrogenase-like    Dimeric isocitrate & isopropylmalate dehydrogenases    NADP-dependent isocitrate dehydrogenase    Pig (Sus scrofa) GO:  isocitrate dehydrogenase (NADP+) activity    oxidoreductase activity    main pathways of carbohydrate metabolism    metabolism

Image Source: PDB

Loops in ArchDB40 clusters

1lwd_A_186 - HE => SUBCLASS : 1.1.2
1lwd_A_236 - HE => SUBCLASS : 1.1.2
1lwd_A_56 - HE => SUBCLASS : 1.3.2
1lwd_A_236 - HE => SUBCLASS : 3.2.2
1lwd_A_291 - HA => SUBCLASS : 5.2.1
1lwd_A_291 - HA => SUBCLASS : 5.2.2
1lwd_A_151 - HA => SUBCLASS : 7.7.1
1lwd_A_265 - EH => SUBCLASS : 1.1.1
1lwd_A_265 - EH => SUBCLASS : 1.1.2
1lwd_A_40 - EH => SUBCLASS : 2.4.2
1lwd_A_40 - EH => SUBCLASS : 2.4.5
1lwd_A_5 - AR => SUBCLASS : 2.1.2
1lwd_A_143 - AR => SUBCLASS : 3.2.15
1lwd_A_143 - AR => SUBCLASS : 3.15.2
1lwd_A_5 - AR => SUBCLASS : 4.5.1
1lwd_A_330 - HH => SUBCLASS : 2.2.1
1lwd_A_47 - HH => SUBCLASS : 2.12.1

Loops in ArchDB95 clusters

1lwd_A_265 - EH => SUBCLASS : 1.1.1
1lwd_A_40 - EH => SUBCLASS : 2.3.3
1lwd_A_207 - EH => SUBCLASS : 5.38.1
1lwd_A_5 - AR => SUBCLASS : 3.1.6
1lwd_A_143 - AR => SUBCLASS : 3.1.13
1lwd_A_5 - AR => SUBCLASS : 4.3.2
1lwd_A_330 - HH => SUBCLASS : 2.2.1
1lwd_A_47 - HH => SUBCLASS : 2.10.1
1lwd_A_186 - HE => SUBCLASS : 1.2.3
1lwd_A_56 - HE => SUBCLASS : 1.2.5
1lwd_A_56 - HE => SUBCLASS : 1.2.6
1lwd_A_236 - HE => SUBCLASS : 2.1.3
1lwd_A_236 - HE => SUBCLASS : 2.1.7
1lwd_A_186 - HE => SUBCLASS : 3.2.1
1lwd_A_291 - HA => SUBCLASS : 5.2.2
1lwd_A_291 - HA => SUBCLASS : 5.2.3
1lwd_A_151 - HA => SUBCLASS : 7.9.1

Loops in ArchDB-EC clusters

1lwd_A_47 - HH => SUBCLASS : 2.9.1

Loops not clustered in ArchDB

1lwd_A_36 - AR
1lwd_A_129 - AR
1lwd_A_166 - AR
1lwd_A_5 - AR
1lwd_A_36 - AR
1lwd_A_129 - AR
1lwd_A_143 - AR
1lwd_A_166 - AR
1lwd_A_303 - EH
1lwd_A_246 - EH
1lwd_A_177 - EH
1lwd_A_70 - EH
1lwd_A_11 - EH
1lwd_A_151 - HA
1lwd_A_107 - HA
1lwd_A_107 - HA
1lwd_A_291 - HA
1lwd_A_18 - HE
1lwd_A_96 - HE
1lwd_A_251 - HE
1lwd_A_271 - HE
1lwd_A_81 - HH
1lwd_A_219 - HH
1lwd_A_313 - HH
1lwd_A_350 - HH
1lwd_A_374 - HH

1lwd A - percentage of sequence identity: 100
1lwd B - percentage of sequence identity: 100
1t09 A - percentage of sequence identity: 70
1t09 B - percentage of sequence identity: 70
1t0l A - percentage of sequence identity: 70
1t0l B - percentage of sequence identity: 70
1t0l C - percentage of sequence identity: 70
1t0l D - percentage of sequence identity: 70