PDB: 1m27 Compound: sh2 domain protein 1a Classification: SIGNALING PROTEIN, TRANSFERASE Entry date in PDB: 2003-05-06 Resolution [Å]: 2.50 R-Factor: 0.213

CHAIN: A SWISS-PROT/TREMBL: O60880    KEYWORD: 3D-structure    Alternative splicing    Disease mutation    SH2 domain    SCOP: d.93.1.1 Alpha and beta proteins (a+b)    SH2-like    SH2 domain    SH2 domain    The Xlp protein Sap    Human (Homo sapiens) GO:  intracellular signaling cascade    CHAIN: B SWISS-PROT/TREMBL: Q13291    KEYWORD: 3D-structure    Alternative splicing    Antigen    Glycoprotein    Immunoglobulin domain    Phosphorylation    Receptor    Repeat    Signal    T-cell    Transmembrane    GO:   CHAIN: C SWISS-PROT/TREMBL: P06241    KEYWORD: 3D-structure    ATP-binding    Lipoprotein    Myristate    Palmitate    Phosphorylation    Polymorphism    Proto-oncogene    SH2 domain    SH3 domain    Transferase    Tyrosine-protein kinase    EC: 2.7.1.112 SCOP: b.34.2.1 All beta proteins    SH3-like barrel    SH3-domain    SH3-domain    Fyn proto-oncogene tyrosine kinase, SH3 domain    Human (Homo sapiens) GO:  ATP binding    protein kinase activity    protein-tyrosine kinase activity    intracellular signaling cascade    protein amino acid phosphorylation

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1d4t A - percentage of sequence identity: 100
1efn A - percentage of sequence identity: 98
1fmk - - percentage of sequence identity: 77
1qcf A - percentage of sequence identity: 61
1shf A - percentage of sequence identity: 100