PDB: 1m6b Compound: receptor protein-tyrosine kinase erbb-3 Classification: SIGNALING PROTEIN, TRANSFERASE Entry date in PDB: 2002-08-02 Resolution [Å]: 2.60 R-Factor: 0.238

CHAIN: A SWISS-PROT/TREMBL: P21860    KEYWORD: 3D-structure    Alternative splicing    ATP-binding    Glycoprotein    Multigene family    Phosphorylation    Receptor    Signal    Transferase    Transmembrane    Tyrosine-protein kinase    EC: 2.7.1.112 SCOP: c.10.2.5 Alpha and beta proteins (a/b)    Leucine-rich repeat, LRR (right-handed beta-alpha superhelix)    L domain-like    L domain    Receptor protein-tyrosine kinase Erbb-3 extracellular domain    Human (Homo sapiens) SCOP: c.10.2.5 Alpha and beta proteins (a/b)    Leucine-rich repeat, LRR (right-handed beta-alpha superhelix)    L domain-like    L domain    Receptor protein-tyrosine kinase Erbb-3 extracellular domain    Human (Homo sapiens) SCOP: g.3.9.1 Small proteins    Knottins (small inhibitors, toxins, lectins)    Growth factor receptor domain    Growth factor receptor domain    Receptor protein-tyrosine kinase Erbb-3 Cys-rich domains    Human (Homo sapiens) SCOP: g.3.9.1 Small proteins    Knottins (small inhibitors, toxins, lectins)    Growth factor receptor domain    Growth factor receptor domain    Receptor protein-tyrosine kinase Erbb-3 Cys-rich domains    Human (Homo sapiens) GO:  membrane    ATP binding    epidermal growth factor receptor activity    protein kinase activity    protein-tyrosine kinase activity    transmembrane receptor protein tyrosine kinase activity    protein amino acid phosphorylation    transmembrane receptor protein tyrosine kinase signaling pathway    CHAIN: B SWISS-PROT/TREMBL: P21860    KEYWORD: 3D-structure    Alternative splicing    ATP-binding    Glycoprotein    Multigene family    Phosphorylation    Receptor    Signal    Transferase    Transmembrane    Tyrosine-protein kinase    EC: 2.7.1.112 SCOP: c.10.2.5 Alpha and beta proteins (a/b)    Leucine-rich repeat, LRR (right-handed beta-alpha superhelix)    L domain-like    L domain    Receptor protein-tyrosine kinase Erbb-3 extracellular domain    Human (Homo sapiens) SCOP: c.10.2.5 Alpha and beta proteins (a/b)    Leucine-rich repeat, LRR (right-handed beta-alpha superhelix)    L domain-like    L domain    Receptor protein-tyrosine kinase Erbb-3 extracellular domain    Human (Homo sapiens) SCOP: g.3.9.1 Small proteins    Knottins (small inhibitors, toxins, lectins)    Growth factor receptor domain    Growth factor receptor domain    Receptor protein-tyrosine kinase Erbb-3 Cys-rich domains    Human (Homo sapiens) SCOP: g.3.9.1 Small proteins    Knottins (small inhibitors, toxins, lectins)    Growth factor receptor domain    Growth factor receptor domain    Receptor protein-tyrosine kinase Erbb-3 Cys-rich domains    Human (Homo sapiens) GO:  membrane    ATP binding    epidermal growth factor receptor activity    protein kinase activity    protein-tyrosine kinase activity    transmembrane receptor protein tyrosine kinase activity    protein amino acid phosphorylation    transmembrane receptor protein tyrosine kinase signaling pathway

Image Source: PDB

Loops in ArchDB-EC clusters

1m6b_A_244 - HA => SUBCLASS : 4.1.3

Loops not clustered in ArchDB

1m6b_A_235 - AR
1m6b_A_77 - AR
1m6b_A_85 - AR
1m6b_A_96 - AR
1m6b_A_114 - AR
1m6b_A_122 - AR
1m6b_A_155 - AR
1m6b_A_298 - AR
1m6b_A_281 - AR
1m6b_A_253 - AR
1m6b_A_68 - AR
1m6b_A_63 - AR
1m6b_A_44 - AR
1m6b_A_529 - AR
1m6b_A_510 - AR
1m6b_A_429 - AR
1m6b_A_409 - AR
1m6b_A_398 - AR
1m6b_A_378 - AR
1m6b_A_373 - AR
1m6b_A_337 - AR
1m6b_A_39 - AR
1m6b_A_266 - AR
1m6b_A_342 - EH
1m6b_A_127 - EH
1m6b_A_434 - EH
1m6b_A_463 - EH
1m6b_A_261 - HA
1m6b_A_523 - HA
1m6b_A_504 - HA
1m6b_A_560 - HA
1m6b_A_9 - HA
1m6b_A_311 - HA
1m6b_A_230 - HA
1m6b_A_290 - HA
1m6b_A_276 - HA
1m6b_A_471 - HE
1m6b_A_346 - HE
1m6b_A_144 - HE
1m6b_A_451 - HE

1m6b A - percentage of sequence identity: 100
1m6b B - percentage of sequence identity: 100
2ahx A - percentage of sequence identity: 60
2ahx B - percentage of sequence identity: 60